Granisetron Granisetron Granisetron Granisetron Granisetron Granisetron
Granisetron
Granisetron Granisetron Granisetron Granisetron Granisetron

Granisetron

600 INR/Gram

Product Details:

  • Taste Odorless
  • Molecular Weight 312.41 Grams (g)
  • Structural Formula C18H24N4O
  • Smell Resinous
  • Storage Room Temperature
  • Shelf Life 36 Months
  • Loss on Drying 0.5 %
  • Supply Ability : 100 Gram Per Week
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Price And Quantity

  • 600 INR/Gram
  • 100 Gram

Product Specifications

  • ANTIVOMETTING
  • 312.41 Grams (g)
  • Odorless
  • Granisetron is a serotonin 5-HT3 receptor antagonist used as an antiemetic to treat nausea and vomiting following chemotherapy. Its main effect is to reduce the activity of the vagus nerve, which is a nerve that activates the vomiting center in the medulla oblongata. It does not have much effect on vomiting due to motion sickness. This drug does not have any effect on dopamine receptors or muscarinic receptors.
  • Resinous
  • 36 Months
  • Room Temperature
  • Medicine Grade
  • C18H24N4O
  • 10 MICRON
  • 99.8 %
  • 0.5 %
  • Granisetron
  • Powder
  • White crystalline powder
  • 0.5 %
  • 109889-09-0

Trade Information

  • Navaseva
  • Letter of Credit at Sight (Sight L/C), Telegraphic Transfer (T/T), Paypal, Cash Against Delivery (CAD), Cash on Delivery (COD), Cash Advance (CA), Cash in Advance (CID), Cheque, Letter of Credit (L/C), Western Union, Delivery Point (DP), Days after Acceptance (DA)
  • 100 Gram Per Week
  • 2 Days
  • Yes
  • Free samples are available
  • Double LDPE Liners in HDPE carboys
  • Western Europe, North America, South America, Middle East, Central America, Eastern Europe, Asia, Australia, Africa
  • Himachal Pradesh, Nagaland, Daman and Diu, Dadra and Nagar Haveli, Lakshadweep, Sikkim, Mizoram, Karnataka, East India, Gujarat, Goa, Rajasthan, Jammu and Kashmir, Delhi, Manipur, Jharkhand, Arunachal Pradesh, Meghalaya, North India, Assam, Tripura, Pondicherry, Telangana, Bihar, Punjab, Chandigarh, Central India, South India, Maharashtra, Andaman and Nicobar Islands, Tamil Nadu, Uttar Pradesh, Haryana, West Bengal, Madhya Pradesh, All India, Andhra Pradesh, Kerala, Odisha, West India, Uttarakhand, Chhattisgarh
  • FDCA, GMP, GLP AND ISO

Product Description

It falls into the class of 5-HT3 receptor antagonists. Serotonin is a natural substance that may cause nausea and vomiting, and Granisetron prevents nausea and vomiting by blocking it. Granisetron is used to treat vomiting and nausea associated with chemotherapy. It has no effect on motion sickness or dopamine receptors. 

Granisetron belongs to the class of 5-HT3 receptor antagonist. Granisetron prevents nausea and vomiting by serotonin which is a natural substance which can cause nausea and vomiting. 

Granisetron used as an antiemetic agent to treat vomiting and nausea in the treatment like chemotherapy. This drug did not have effect in motion sickness and it will not effect on dopamine receptors. 

SYNONYMS OF GRANISETRON:  Granisetron,Granisetronum 

IUPAC NAME: 1-Methyl-N-((1R, 3r, 5S)-9-methyl-9-azabicyclononan-3-yl)-1H-indazole-3-carboxamide 

CAS NO: 109889-09-0 

MOLECULAR FORMULA: C18H24N4O 

MOLECULAR MASS: 312.41 g/mol 

STORAGE OF GRANISETRON: Keep medication is cool and dry place, do not store in bathroom or kitchen. Keep all medication away from children and pets 

HOW TO USE: Granisetron comes in oral dosage form like tablet; it is consumed by mouth with water. Take the medicine 1hr before the chemotherapy. And take second dose after the 12hr interval of first dose. 

HOW GRANISETRON WORKS: Granisetron gives antiemetic activity by inhibiting the 5-HT3 receptor which are located in centrally and peripherally in the body. By this process the natural serotonin secretion inhibited and by this the nausea and vomiting is prevented. 

PHARMACOKINETICS OF GRANISETRON: The main absorption of Granisetron is done by the oral and it is rapid and complete. As the result of first pass metabolism the oral bioavaibility is reduced about 60%. The half-life of Granisetron in the cancer patients is 9-12hrs and in the normal patient the half-life is 4-6 hrs. The 48% excretion of Granisetron is done by urination and remaining will excreted in faces. 

SIDE EFFECTS OF GRANISETRON: There are some common side effects of Granisetron is headache, dizziness, fever, pain,redness and swelling on the injection point. Tell your doctor if you see side effects like stomach/abdominal pain, chest pain, fast irregular heartbeats,hallucination, loss of coordination, muscle pain etc. The allergic reactions by the Granisetron are rare but if you develop symptoms like rash, itching or irritation consult your doctor. 

PRECAUTIONS: Tell your doctor if you are allergic to Granisetron or its residues. Before using the Granisetron tell your doctor if you have any past related to stomach or intestinal problem like swelling or surgery. Tell your doctor if you have certain history related to heart problems. Talk to your doctor about taking Granisetron safely. 

CDSCO APPROVAL OF GRANISETRON: Granisetron tablets are approved by CDSCO in India in 05.07.2000

 

FORMULATIONS AVAILABLE IN MARKET:

Granisetron 1mg tablets

Granisetron 1mg/ml injection

Granisetron 2mgtablets

Granisetron 1mg/5ml injection

Granisetron 3mg/3ml injection

Granisetron 500mg tablets

 

Note: Product protected by valid patents are not offered for sale in countries where such patents are still valid and its liability is at Buyers Risk

 

REFERENCES: 

www.webmd.com

https://pubchem.ncbi.nlm.nih.gov

https://go.drugbank.com

https://cdscoonline.gov.in

https://www.wikipedia.org/

https://www.drugs.com

https://www.zaubacorp.com

https://www.practo.com/consult

 

 

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