LUMEFANTRINE

Product Description

Niksan Pharmaceutical is one of the leading manufacturer,supplier and exporter of the Lumefantrine.The best product manufactured by Niksan Pharmaceutical is Lumefantrine. We manufacture, supply and exportbest quality product of Lumefantrine API along with Lumefantrine formulations.

Niksan Pharmaceutical is also manufacture and exports largequantity of Lumefantrine products in whole globe since many years incountries like Nepal, United Arab Emirates, South Korea, Philippines,Bangladesh, Australia, United States, United Kingdom, Bulgaria, Georgia,Germany, Ghana, Greece, Grenada, Guatemala, Guinea, Guinea-Bissau, Guyana,Haiti, Honduras, Hungary, Iceland, , Indonesia, Iran, Iraq, Ireland, Israel,Italy, Jamaica, Colombia, Comoros, Democratic Republic of the Congo, Republicof the Congo, Costa Rica, Cote d’Ivoire, Croatia, Cuba, Cyprus, Czech Republic,Denmark, Djibouti, Dominica, Dominican Republic, East Timor (Timor-Leste),Ecuador, Egypt, El Salvador, Equatorial Guinea, Eritrea, Japan and Jordan, Kazakhstan,Kenya, Kiribati, North Korea, South Korea, Kosovo, Kuwait, Kyrgyzstan, LaosBurkina Faso, Burundi, Estonia, Eswatini, Ethiopia, Mauritius, Mexico, Lebanon,Lesotho, Liberia, Libya, Liechtenstein, Maldives, Mali, Malta, MarshallIslands, Mauritania,  Peru, Philippines,Poland,  Micronesia, Moldova, Monaco,Mongolia, Montenegro, Morocco, Mozambique, Myanmar (Burma), Namibia, Nauru,Nepal, Netherlands, New Zealand, Nicaragua, Niger, Nigeria, North Macedonia,Norway, Oman, Pakistan, Palau, Panama, Papua New Guinea, Paraguay, Fiji,Finland, France, Gabon, The Gambia, , Latvia, Portugal, Qatar, Romania, Russia,Rwanda, Saint Kitts and Nevis, Saint Lucia, Saint Vincent and the Grenadines,Cabot Verde, Cambodia, Cameroon, Canada, Central African Republic, Chad, Chile,China, Samoa, San Marino, Sao Tome and Principe and Saudi Arabia and many othercountries.

Niksan Pharmaceutical provides best quality product of Lumefantrine in all states of Indialike Kerala,Punjab, Rajasthan, Delhi, Tamil Nadu, Odisha, Madhya Pradesh,Telangana, Bihar,Karnataka, Jammu and Kashmir, Maharashtra, West Bengal, Uttar Pradesh,Gujarat,  Andhra Pradesh, Haryana  and many other states.

Lumefantrine is the antimalarial drug. Lumefantrineused in the treatment of malaria caused by the mosquito bite. Lumefantrine ismember of monochlorobenzenes. It is secondary alcohol. Lumefantrine belongs tothe medicine class called fluorenes.

SYNONYMS: Benflumetol, dl-Benflumelol, Lumefantrine

IUPAC NAME: 2-(dibutylamino)-1-[(9Z)-2,7-dichloro-9-[(4-chlorophenyl) methylidene]-9H-fluoren-4-yl]ethan-1-ol

CAS NO: 82186-77-4

FORMULA: C₃₀H₃₂Cl₃NO

MOLECULAR MASS: 528.94 g/mol

STORAGE CONDITIONS: Store in roomtemperature in dry place. Do not keep medication in humid place or bathroom. Keepmedication away from direct light and heat. Keep away from children and pets.

HOW TO USE: Take medication 2times per day with meal for three day. Take your doctor’s advice before takingthe medication. If you vomit after taking the drug, take medicine again after30 minutes.

HOW LUMEFANTRINEWORKS: Lumefantrine kills the plasmodium parasites by inhibiting the nucleicacid synthesis inside them. And by this process Lumefantrine gives antimalarialeffect to the patient.

PHARMACOKINETICS:Lumefantrine have good absorption rate inthe body, it absorbs more when taken with meal. Lumefantrine bounds with almost99.7% of plasma proteins. The half-life of Lumefantrine is 4.5days. TheLumefantrine metabolizes by the liver and after that it is eliminated throughthe bile. The elimination half-life of Lumefantrine is 3-6 days.

SIDE EFFECTS: The side effects of Lumefantrine arefever, chills, muscle pain, nausea, vomiting, headache, abdominal pain,insomnia, cough, dizziness and many more. Contact your doctor if you see sideeffects like fainting, chest pain, and dizziness, fast or irregular heartbeat. Theallergic reaction of this drug is rare but if you see effects like rash,itching, or swelling of skin.

PRECAUTIONS: Lumefantrine cause heart problems soconsult your doctor before taking the medication. Tell your doctor if you areallergic to Lumefantrine or inactive ingredients. Take medical attention rightaway if you see any effects like dizziness, fainting, fast irregular heartbeatsor any heart problem. If you have conditions such as sweating, vomiting, motionsickness tell your doctor about it.

CDSCO APPROVAL: Artemether + Lumefantrine approved by CDSCO in India in 26.12.2002,

Artemether 40mg/80mg + Lumefantrine 240mg/480mg tablets(additional Strength) approved by CDSCO in India in 24.06.2008,

 Artemether + LumefantrineDispersible tablet (40/80mg + 240/480mg) (Additional Strength) approved byCDSCO in India in 05.08.2008,

Artemether + Lumefantrine (80mg + 480mg/5ml) Dry syrupapproved byCDSCO in India in 30.09.2008

FORMULATIONS AVAILABLE IN MARKET:

Artemether 80mg + Lumefantrine 480mg tablets

Artemether 20mg + Lumefantrine 120mg/ml oral solution

Artemether40mg + Lumefantrine240mg tablets

Artemether 20mg + Lumefantrine 120mg tablets

Artemether 40mg + Lumefantrine 240mg/5ml oral solution

Note: Product protected by valid patents are notoffered for sale in countries where such patents are still valid and itsliability is at Buyers Risk

REFERENCES:

www.webmd.com

https://pubchem.ncbi.nlm.nih.gov

https://go.drugbank.com

https://cdscoonline.gov.in

https://www.wikipedia.org/

https://www.drugs.com

https://www.zaubacorp.com

https://www.practo.com/consult