ROSUVASTATIN

Product Description

The drug Rosuvastatin is part of the statins* group, which is used in treating high cholesterol and fat levels. This drug helps to increase good cholesterol in the blood as well. As a result of Rosuvastatin, liver cholesterol is reduced. This can assist in a healthy diet. Take one tablet each day. It can be taken at any time of the day with or without food.

Niksan Pharmaceutical provides API and finished formulation of Rosuvastatin in many Indian states like Himachal Pradesh, Andhra Pradesh, Tamil Nadu,Telangana, Kerala, Karnataka, Gujarat, Jammu & Kashmir, Chandigarh, Punjab,Uttarakhand, Chhattisgarh, Haryana, Maharashtra, Odisha, Uttar Pradesh, Delhi,Rajasthan, Madhya Pradesh, West Bengal, Bihar, Assam and many other Indian states.

Niksan Pharmaceutical is also huge exporter of the API and finished formulations of Rosuvastatin in many Countries like Canada, Philippines, Trinidad& Tobago, Hungary, Nepal Australia, Lebanon, Sri Lanka, Finland, Pakistan, Puerto Rico, Bangladesh, United States, United Arab Emirates, Vietnam, Iraq,ï  South Korea, Nigeria, Jordan, Switzerland,Slovenia, Hong Kong, Malaysia, Saudi Arabia, United Kingdom, Israel, Sweden,Germany, Greece, Egypt, Czechia, Thailand, Indonesia, South Africa, Denmark,Romania and many other countries.

Rosuvastatin belongs to a group of drugs statins which is used in diet of bad cholesterol and fats. It also increases good cholesterol in the blood.

SYNONYMS: Rosuvastatin,Rosuvastatina

IUPAC NAME: (3R,5S, 6E)-7-[4-(4-fluorophenyl)-2-(N-methylmethanesulfonamido)-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid

CAS NO: 287714-41-4

FORMULA: C₂₂H₂₈FN₃O₆S

MOLECULAR MASS: 481.53g/mol

STORAGE OF Rosuvastatin: Store in col and dry place. Keep medicine away from the reach of children and pets. Do not store this medicine in bathroom or any humidly place.

APPLICATIONS OF Rosuvastatin: Rosuvastatin is used in diet of bad cholesterol and fats. It is also increase good cholesterol in the blood.

HOWTO USE: Take one tablet in one day. You can take Rosuvastatin every day at any time.

Take this medication with or without food.

HOW Rosuvastatin WORKS: Rosuvastatin reducing the amount of cholesterol which made by liver. Which can helps you in good diet. 

CONTRAINDICATIONS: If you are a patient of liver problem or liver failure kindly avoid this medication. If you have a chronic kidney disease or metabolic syndrome x do not take this medication. Kindly avoid Rosuvastatin if you have recent operation and major traumatic injury.

PHARMACOKINETICS OF Rosuvastatin: Approximately 20% Rosuvastatin absorbed after oral administration. Half life of Rosuvastatin is approximately 19 hours. Rosuvastatin is not widely metabolized. Maximum time of Peak plasma concentration of Rosuvastatinis 3 to 5 hours. Approximately 78% Rosuvastatin is excreted vi bile and 28%excreted by renal excretion.

SIDE EFFECTS OF Rosuvastatin: Many people use this drug but very few side effects are seen in the patient. In ther are case Rosuvastatin cause worsen diabetes. This drug may rarely cause muscle problem like muscle pain and weakness.

PRECAUTION: During the pregnancy do not use Rosuvastatin it may harm and unborn baby. Consult with your doctor before the breast-feeding. Do not take alcohol and do not driving during the dose. Do not take this medication if you have any liver problem.

CDSCO APPROVAL: Rosuvastatin Calcium eq. to Rosuvastatin 20mg/20mg + Fenofibrate BP 67.5mg/145mg Tablets are approved by CDSCO in India in 24.08.2011

Rosuvastatin Calcium Tablet (Additional Indication) is approved by CDSCO in India in 24.05.2010

Rosuvastatin Calcium IP eq to Rosuvastatin 5mg + Ezetimibe 10mg. (Additional Strength) is approved by CDSCO in India in 05.12.2011

Rosuvastatin 5/10/20mg + Fenofibrate 67/145/160mg is approved by CDSCO in India in 23.08.2010

Rosuvastatin Calcium tablets 5/10/20/40mg (Addl. Indication) is approved by CDSCO in Indiain 08.11.2008

Rosuvastatin Calcium IP 5mg/10mg + Fenofibrate BP 160mg/160mg tablet is approved by CDSCO in India in 29.12.2010

Rosuvastatin calcium tablet is approved by CDSCO in India in 2003

Aspirin(EC Tablets) 75mg/75mg/150mg + Rosuvastatin (Granules) 5mg/10mg/10mg Capsules is approved by CDSCO in India in 30.03.2011

Rosuvastatin Calcium Tablets 5/10/20mg (Additional Indication) is approved by CDSCO in India in 05.04.2011

FORMULATIONS AVAILABLE IN MARKET:

Rosuvastatin 10 MG tablets

Rosuvastati n 20 MG tablets

Rosuvastatin 40 MG tablets

Rosuvastat in 5 MG tablets

Rosuvastatinï  30 MG tablets

Rosuvastatin 15 MG tablets

Rosuvastatin 10 MG+Aspirin 75ï  MG tablets

Rosuvastatin 5 MG+Fenofibrate 67 MG tablets

Rosuvastatin 10 MG+Fenofibrate 67 MG tablets

Clopidogrel 75 MG +Rosuvastatin 10 MG tablets

Fenofibrate 67 MG+Rosuvastatin 20 MG tablets

Clopidogrel 75 MG+Rosuvastatin 20 MG tablets

Aspirin 75MG+Rosuvastatin 20 MG tablets

Clopidogrel 75 G+Rosuvastatin 5 MG tablets

Rosuvastatin 10 MG+Ezetimibe 10 MG tablets

Note: Product protected by valid patents are not offered for sale in countries where such patents are still valid and its liability is at Buyers Risk.

REFERENCES:

www.webmd.com

https://pubchem.ncbi.nlm.nih.gov

https://go.drugbank.com

https://cdscoonline.gov.in

https://www.wikipedia.org/

https://www.drugs.com

https://www.zaubacorp.com

https://www.practo.com/consult