MEMANTINE

Product Description

anantagonist of the NMDA (N-Methyl-D-Aspartate)-receptorsubtype of glutamate receptor. It is used toslow the neurotoxicity thought to be involved in Alzheimer disease and otherneurodegenerative diseases.

Memantina, Memantine, Memantinum

IUPAC NAME: 3,5-dimethyladamantan-1-amine

CAS NO: 19982-08-2

FORMULA: C₁₂H₂₁N

MOLECULAR MASS:179.30 g/mol

STORAGE OF MEMANTINE:Keepthis drug at a temperature between 59°F and 77°F (15°C and 25°C). Keep this drug away from light and high temperature.Don't store this medication in moist or damp areas, such as bathrooms.

APPLICATIONS OF MEMANTINE Memantine is amedication that comes in a tablet form. It treats dementia caused by Alzheimer's disease. Dementia affects your thinking, memory, reasoning,personality, mood and behavior. 

HOW TO USE: Memantine comes as a tablet, a solution(liquid), and an extended-release (long-acting) capsule to take by mouth. Thesolution and tablet are usually taken once or twice a day with or without food.

MEMANTINE WORKS: Memantineworks by blocking theeffects of a chemical called glutamate.Glutamate sends messages between nerve cells in the brain. Nerve cells damagedby Alzheimer's disease make too much glutamate which can cause more damage.Memantine protects nerve cells by blocking the effects of too much glutamate.

MEMANTINE: Memantine is used to treat the symptoms of Alzheimer's disease (AD; a brain disease that slowly destroys thememory and the ability to think, learn, communicate and handle dailyactivities). Memantine is in a class of medications called NMDA receptorantagonists. It works by decreasing abnormal activity in the brain.

MEMANTINE: Memantine is wellabsorbed after oral administration and has linear pharmacokinetics over the therapeutic dose range. It is excreted predominantly in the urine, unchanged,and has a terminal elimination half life of about 60-80 hours.

MEMANTINE:  Memantine is not a cure for dementia butit can help with symptoms like being forgetful, feeling confused or feelinganxious. The most common side effects of memantine are feeling sleepy or dizzy, headaches, nervousness,pounding in the ears, constipation and shortness of breath.

PRECAUTIONS: This medication contains memantine, Do nottake Namenda XR or Namenda if you are allergic to memantine or any ingredientscontained in this drug.Keep out of reach of children, In case of overdose, getmedical help or contact a Poison Control Center immediately.

CDSCO APPROVAL:

Memantine hcl tablets are approved by CDSCO in India in 22/07/2004

FORMULATION AVAILABLEIN MARKET:

Memantine hcl tabs.

Memantine HCl ER Tablet 28mg

Memantine ER Tablet 7mg/14mg/21mg.

Memantine 5mg /10mg + Donepezil 5mg Tablets

Note: Product protected by validpatents are not offered for sale in countries where such patents are stillvalid and its liability is at Buyers Risk

REFERENCES:

www.webmd.com

https://pubchem.ncbi.nlm.nih.gov

https://go.drugbank.com

https://cdscoonline.gov.in

https://www.wikipedia.org/

https://www.drugs.com

https://www.zaubacorp.com

https://www.practo.com/consult