CITICOLINE

9000.00 INR/Kilograms

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Product Details:

HS Code 29420090
Molecular Weight 488.12 g/mol Grams (g)
Loss on Drying typically less than 5%
Boiling point 851.4C at 760 mmHg
Taste Sweet
Smell Other
Molecular Formula C16H20N4O3S
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CITICOLINE Price And Quantity

Price Range 12000.00 - 18000.00 INR/Kilograms
Price 9000.00 INR/Kilograms
Minimum Order Quantity 1 Kilograms

CITICOLINE Product Specifications

Molecular Formula C16H20N4O3S
EINECS No 213-580-7
Smell Other
Purity(%) 99 %
HS Code 29420090
Molecular Weight 488.12 g/mol Grams (g)
Boiling point 851.4C at 760 mmHg
Taste Sweet
Loss on Drying typically less than 5%
Particle Size 50-100 microns
Melting Point 259-268C
Storage Room Temperature
Grade Medicine Grade
Chemical Name CITICOLINE
Heavy Metal (%) NA
Usage Citicoline has most often been used by adults in doses of 500-1000 mg by mouth twice daily for up to 12 months. Speak with a healthcare provider to find out what dose might be best for a specific condition.
Ph Level between 6.5 and 7.5 for a 1% solution
Medicine Name CITICOLINE
Type Other
Solubility Freely soluble in water and insoluble in methanol.
Shelf Life 3 Years
CAS No 987-78-0
Physical Form Powder
Structural Formula C16H20N4O3S
Appearance White to Off-White Solid

CITICOLINE Trade Information

FOB Port INDIA
Payment Terms Cash Advance (CA), Cheque
Supply Ability 100 Kilograms Per Month
Delivery Time 1 Days
Sample Available No
Packaging Details HDPE DRUM WITH TWO INNER LDPE LINNER
Main Export Market(s) Western Europe, Middle East, Africa, Asia, Australia, Central America, North America, South America, Eastern Europe
Main Domestic Market All India
Certifications GMP, FDCA

Product Description

is leading manufacturer and distributer ofthe Citicolineamong the other countries. NiksanPharmaceutical is one of the major the supplier, distributer, exporter andmanufacturer of the CiticolineAPI and finished formulations in Ankleshwar, Gujarat, India. The products ofNiksan Pharmaceutical and Niksan group companies are widely appreciated by theclients and other companies.

NiksanPharmaceutical is the supplier, manufacturer, exporter andtrader of Citicoline in thedomestic level as well as the international market.

NiksanPharmaceutical provides Citicoline API inall over Indian states like Jammu & Kashmir, Himachal Pradesh, Uttarakhand,Punjab, Kerala, Chandigarh, Chhattisgarh, Andhra Pradesh, Rajasthan, Meghalaya, Mizoram,Nagaland, Orissa,, Dadra and Nagar Haveli, Goa,Gujarat, Jharkhand, West Bengal, Karnataka, Kerala, Madhya Pradesh etc.

NiksanPharmaceutical alsoprovides Citicoline API and finished formulations inall other countries of the world like Germany, Switzerland, Poland, Latvia,Egypt, Lithuania, Estonia, Ukraine, Moldova, Russia, United States, Austria,Belarus, Serbia, India, Spain, Slovenia, Nigeria, Croatia, South Africa,Kazakhstan, Italy, Romania, Bulgaria, Portugal, South Korea, Greece,Philippines, Belgium, Saudi Arabia, Turkey, Japan etc.

Citicoline is onetype of diuretic medication which is used to treat stroke, head trauma or injury, Alzheimers disease, Parkinsonsdisease, and glaucoma. A stroke occurs due to insufficient blood supply to thebrain. Alzheimers disease is a progressive age-related memory loss.

SYNONYMS:CDP-Choline, CDP-Cholina, Citicolina, Citicoline, Citidin Difosfato De Colina

IUPAC NAME:{2-[({[(2R,3S,4R,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphorylphosphono)oxy]ethyl}trimethylazanium

CASNO: 987-78-0

FORMULA:C₁₆H₂₀N₄O₃S

MOLECULARMASS:488.12g/mol

STORAGE OF CITICOLINE:Keep container tightly closed in a dry andwell-ventilated place.

APPLICATIONSOF CITICOLINE: Uses of citicoline forage-relateddecline in memory and thinking, glaucoma, stroke, Alzheimer disease, bipolardisorder, depression, and many other conditions,but there is no good scientific research to support most of these uses.

HOWTO USE: Citicoline hasmost often been used by adultsindoses of 500-1000 mg by mouth twice daily for up to 12 months. Speak with a healthcare provider to find out whatdose might be best for a specific condition.HOWCITICOLINE WORKS:Citicoline seems toincrease a brain chemical calledphosphatidylcholine. Citicoline might alsoincrease the amounts of other chemicals that send messages in the brain. It wasoriginally used as a drug to help improve memory and brain function after astroke.

CONTRAINDICATIONSOF CITICOLINE: Avoid giving high dose citicoline (>500 mg) inintracranial bleeding.Pregnancy and lactation. Cardiac disorders: Bradycardia, tachycardia. Eyedisorders: Diplopia.

PHARMACOKINETICSOF CITICOLINE: Citicoline iswater-soluble,with more than 90% oral bioavailability. Plasmalevels peak one hour after oral ingestion, and a majority of the citicoline isexcreted as CO₂in respiration, and again 24 hours afteringestion, where the remaining citicoline is excreted through urine.

SIDE EFFECTS OF CITICOLINE: Citicolinewas well tolerated in clinical trials. Adverse effects may includeGI disturbances, transient headaches, hypotension, tachycardia, chest pain, irregular heartbeats,bradycardia, and restlessness.

PRECAUTIONS: Pregnancy and breast-feeding: There isnt enough reliable information to know if citicoline is safeto use when pregnant or breast-feeding. Stay on the safe side and avoid use.Children: Citicoline is possibly safe when taken by mouth for up to 1 year inchildren up to 13 years of age.

CDSCO APPROVAL:

Citicoline 200mg tablet are approved by CDSCO in 25.05.07

FORMULATION AVAILABLE IN MARKET:

Citcoline 250 MG injection

Citcoline 125 MG injection

Citicoline 500 MG/5 MLsyrup

Citicoline sodium 500 MG/5ML syrup

Citicoline sodium IP 500 MG +piracetam IP 800 MG

Note: Productprotected by valid patents are not offered for sale in countries where suchpatents are still valid and its liability is at Buyers Risk

REFERENCES:

www.webmd.com

https://pubchem.ncbi.nlm.nih.gov

https://go.drugbank.com

https://cdscoonline.gov.in

https://www.wikipedia.org/

https://www.drugs.com

https://www.zaubacorp.com

https://www.practo.com/consult

Exceptional Purity and Quality

Citicoline is presented in powder form with a verified purity of 99%, ensuring dependable quality for medicinal applications. Its particle size of 50100 microns allows for easy dissolution, while its stable shelf life of up to 3 years ensures long-term efficacy when stored at room temperature.

Key Applications in Cognitive Support

This medicine-grade compound is widely used to aid cognitive function, memory, and neural health. Citicolines benefits are sought after by those seeking to support mental clarity and may be recommended for neurological conditions, always under professional supervision.

Handling and Safety Guidelines

Citicoline should be stored in a cool, dry area at room temperature, away from excessive humidity. With a pH level between 6.5 and 7.5 (in a 1% solution) and a loss on drying typically less than 5%, it maintains its stability for reliable use in pharmaceutical processes.

FAQs of CITICOLINE:

Q: How should citicoline powder be stored to maintain its effectiveness?

A: Citicoline should be stored at room temperature in a dry, well-ventilated environment. Keeping it in an airtight container protects it from moisture and environmental contaminants, helping preserve its 3-year shelf life.

Q: What is the recommended usage process for citicoline?

A: Adults most commonly use citicoline in doses of 5001000 mg taken by mouth twice daily for up to 12 months. It is essential to consult a healthcare provider for dosage tailored to individual health conditions before starting supplementation.

Q: When is citicoline typically prescribed or used?

A: Citicoline is frequently used to support cognitive function, memory, and neurological health, especially during periods of cognitive decline or recovery after certain neurological injuries, under medical guidance.

Q: Where can citicoline be sourced?

A: Citicoline is available through reputable distributors, importers, exporters, manufacturers, suppliers, and traders in India, ensuring accessibility for both industrial and medicinal purposes.

Q: What benefits can be expected from using citicoline?

A: Citicoline may offer benefits such as improved memory, enhanced focus, and support for overall cognitive health. The extent of benefits depends on individual health conditions and adherence to professional guidance.

Q: How is citicoline processed for medicinal use?

A: Citicoline is manufactured as a white to off-white powder with a specific particle size (50100 microns) and high solubility in water. Its production adheres to strict quality standards to ensure purity and medicinal-grade effectiveness.

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Plot No. 4706/03, Gidc Estate, SF-12, Shrinathji Arcade, Near Meghmani Chowkadi,Ankleshwar - 393002, Gujarat, India
Phone :91--9537871777
Email : info@niksanpharmaceutical.com

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