FENOFIBRATE

Product Description

NiksanPharmaceutical and our group companies Niksan healthcare are the one of largestmanufacturer, exporter and supplier of Fenofibrateformulations and Fenofibrate API in Ankleshwar, Gujarat, India. We aresullying the best quality of Fenofibrate API all around the India as well as inthe whole world. Our product Fenofibrate praised by our clients and also by theother companies.

Niksan Pharmaceutical is theworld leading manufacturing and supplying company of the Fenofibrate products and API.

Thus we are Indian based company we supplying our best quality products ofFenofibrate  to every states of India formany years like Jammu and Kashmir, Kerala, Punjab, Rajasthan, Andhra Pradesh,Haryana, Telangana, Bihar, Karnataka, Delhi, Tamil Nadu, Odisha, Maharashtra,West Bengal, Uttar Pradesh, Gujarat, Madhya Pradesh, Himachal Pradesh, Goa,Chhattisgarh etc.

NiksanPharmaceutical also export huge quantity of best quality Fenofibrate  API products tothe other nations like Puerto Rico,Philippines, United State, Nepal, Singapore, Lebanon, Indonesia, India,Bangladesh, Canada, United Arab Emirates, Sri Lanka, France, Jordan, Taiwan ,Malaysia, Vietnam, Thailand, Saudi Arabia, Australia , Pakistan, Iraq, SouthKorea, Hong Kong, Ireland, United Kingdom Algeria, Egypt, Belgium, Iran,Israel, Mexico, Germany, Turkey, Japan, Brazil and many south easterncountries.

Fenofibrate comes in the anti lipidemic class of medication. Fenofibrate lowers theLDL (low density lipoproteins) which is also called bad cholesterol.  Fenofibrate increase the natural substancewhich cause degradation of the fats in the blood.

SYNONYMS: Fenofibrat, Fenofibrato, Fenofibratum,Finofibrate, Procetofen.

IUPAC NAME: Propan-2-yl 2-[4-(4-chlorobenzoyl) phenoxy]-2-methylpropanoate

CAS NO: 49562-28-9

FORMULA:C₂₀H₂₁ClO₄

MOLECULAR MASS: 360.83 g/mol

STORAGE CONDITIONS: Store in cool and dry place, keep away from directheat and light. Do not store in bathroom or kitchen.  Keep away from children and pet.

HOW TO USE: Take Fenofibrate by mouth one time per daywith or without food. Take medicine with food or milk if you feel stomachupset. Take your doctor’s advice if you have any confusion about medicine.

HOW FENOFIBRATEWORKS: Fenofibrate lowers the bad cholesterol levelby increasing the development of natural enzymes who breaks the fat or LDL inthe blood. Fenofibrate lowers the bad cholesterols like LDL and triglycerideand increase the good cholesterol like HDL in body.

PHARMACOKINETICS: Fenofibrate rapidly absorbed in the bodyafter the oral administration. It takes Fenofibrate 4-6 hours to reach the peakplasma concentration. Almost 99% of Fenofibrate binds with the blood plasmaproteins. The half-life of Fenofibrate is about 19-27 hours in the normalpatient and 143 hours in the patient with renal failure. The 60-88%of Fenofibrateeliminate through urination and 5-25% if Fenofibrate eliminate by the feces.

SIDE EFFECTS OF FENOFIBRATE: There are no many side effects of Fenofibrateis seen in the patient. Some side effects like kidney stone and liver problemsare seen in some patients. Tell your doctor if you see some side effects likenausea and vomiting, stomach or intestinal pain, abdominal irritation, yelloweyes or skin and black urine. This drug rarely because effects like musclepain, weakness in body and kidney problems.

PRECAUTIONS: The main precaution is keep check your HDLlevel. Tell your doctor if you have allergic reactions toward the Fenofibrate medicationor its metabolite. If you have and disease like kidney problem, abdominalproblem, liver problem or heart problem tell your doctor before writing theprescription. Do not take medication if you are in pregnancy period or inlactation period.

CDSCO APPROVAL: Rosuvastatin Calcium eq. to Rosuvastatin20mg/20mg + Fenofibrate BP 67.5mg/145mg Tablets approved by CDSCO in Indian in24.08.2011,

Atorvastatin + Fenofibrate approved by CDSCO in Indian in24.12.2004,

Atorvastatin 5mg + Fenofibrate 160mg (additional strength)approved by CDSCO in Indian in 01.12.2006,

Atorvastatin Calcium (10mg) + Fenofibrate (145mg) (addl. strength)approved by CDSCO in Indian in 30.10.2007,

Ezetimibe 10 mg + Fenofibrate 145 mg Film coated tablets approvedby CDSCO in Indian in 01.09.2009,

FDC of Atorvastatin + fenofibrate approved by CDSCO in Indian in01.08.2006,

Rosuvastatin 5/10/20mg + Fenofibrate 67/145/160mg approved byCDSCO in Indian in 23.08.2010

Choline Fenofibrate DR Capsule 45mg/135mg & DR Tablet45mg/135mg. approved by CDSCO in Indian in 01.11.2012,

Rosuvastatin Calcium IP 5mg/10mg + Fenofibrate BP 160mg/160mgtablet approved by CDSCO in Indian in 29.12.2010,

Atorvastatin 10mg + Fenofibrate 80mg tablet (AdditionalIndication) 25.01.2008,

Metformin HCl ER 500mg + Fenofibrate 80mg/160mg tablet approved byCDSCO in Indian in 25.01.2008,

Fenofibrate capsules approved by CDSCO in Indian in 22.12.1999,

Ezetimibe 10mg + Fenofibrate 160mg tablet approved by CDSCO inIndian in 04.04.2007

FORMULATIONS AVAILABLE IN MARKET:

Fenofibrate 45mg tablets

Fenofibrate 35mg tablets

Fenofibrate 67mg tablets

Ezetimibe 10mg + Fenofibrate 160mg tablets

Fenofibrate capsules

Atorvastatin 10mg + Fenofibrate 80mg tablets

Rosuvastatin Calcium IP 5mg + Fenofibrate BP 160mg tablets

Rosuvastatin Calcium IP10mg + Fenofibrate BP 160mg tablets

Ezetimibe 10 mg + Fenofibrate 145 mg Film coated tablets

Atorvastatin 5mg + Fenofibrate 160mg tablets

Note: Product protected by valid patents are notoffered for sale in countries where such patents are still valid and itsliability is at Buyers Risk

REFERENCES:

www.webmd.com

https://pubchem.ncbi.nlm.nih.gov

https://go.drugbank.com

https://cdscoonline.gov.in

https://www.wikipedia.org/

https://www.drugs.com

https://www.zaubacorp.com

https://www.practo.com/consult