Bosentan

175000 INR/Kilograms

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Product Details:

Particle Size 10 MICRON
Molecular Formula C27H29N5O6S
Loss on Drying 0.5 %
Heavy Metal (%) 0.5 %
Molecular Weight 551.614 g/mol Grams (g)
Taste Odorless
Smell No Smell
Supply Ability : 100 Kilograms Per Week
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Price And Quantity

Price 175000 INR/Kilograms
Minimum Order Quantity 1 Kilograms

Product Specifications

Particle Size 10 MICRON
Molecular Formula C27H29N5O6S
Loss on Drying 0.5 %
Purity(%) 99.8 %
Medicine Name Bosentan
Physical Form Powder
CAS No 147536-97-8
Appearance White crystalline powder
Heavy Metal (%) 0.5 %
Chemical Name Bosentan Monohydrate
Type Cardiovascular Agents
Usage Bosentan is a dual endothelin receptor antagonist used in the treatment of pulmonary artery hypertension
Molecular Weight 551.614 g/mol Grams (g)
Taste Odorless
Shelf Life 36 Months
Storage Room Temperature
Grade Medicine Grade
Smell No Smell

Trade Information

FOB Port SAHAR AIR CARGO
Payment Terms Cash Against Delivery (CAD), Cash on Delivery (COD), Cash Advance (CA), Delivery Point (DP), Letter of Credit (L/C), Letter of Credit at Sight (Sight L/C), Telegraphic Transfer (T/T), Western Union, Paypal, Cash in Advance (CID), Cheque, Days after Acceptance (DA)
Supply Ability 100 Kilograms Per Week
Delivery Time 2 Days
Sample Available Yes
Sample Policy Free samples are available
Packaging Details Double LDPE Liners in HDPE carboys
Main Export Market(s) South America, Western Europe, Asia, Australia, North America, Eastern Europe, Middle East, Africa, Central America
Main Domestic Market Chandigarh, Himachal Pradesh, Nagaland, Daman and Diu, Dadra and Nagar Haveli, Lakshadweep, Delhi, Arunachal Pradesh, Karnataka, Tripura, Telangana, Andhra Pradesh, Goa, Meghalaya, Kerala, Tamil Nadu, Bihar, West Bengal, Andaman and Nicobar Islands, Maharashtra, Mizoram, East India, Sikkim, Gujarat, Jharkhand, South India, Rajasthan, Pondicherry, Assam, Punjab, Jammu and Kashmir, North India, Manipur, Uttar Pradesh, Haryana, Madhya Pradesh, All India, Central India, Odisha, West India, Uttarakhand, Chhattisgarh
Certifications FDCA, GMP, GLP AND ISO

Product Description

The endothelin receptor antagonist bosentan belongs to this class. It increases blood flow in patients with PAH. It is typically taken once in the morning and once in the evening. To take medication, swallow it with or without water. Dissolve the tablet in a small amount of water and drink the liquid immediately after it dissolves. Store it away from heat, and direct sunlight. Do not store it in humid areas such as the bathroom.

147536-97-8

FORMULA: C272956

Store in cool and dry place,keep away from direct heat and light. Do not put in humid place like bathroom. Keep away from children and pet.

HOW TO USE: Take this medicine 2 times per day, normally in morning and evening.Take medicines by mouth with or without water. Put you tablet in small amount of water and dissolve it, when it dissolves drink whole mixture at once.

PHARMACOKINETICS:Bosentan have very low solubility so Bosentan absorbed when it taken in high amount. The drug binds with almost 98% of plasma protein. Bioavailability of this medicine is 505 and it is not affected by food. Half-life of Bosentan in health person is 5 hrs. The Bosentan excited by the biliary excretion.

SIDE EFFECTS OF BOSENTAN: Runny nose, dizziness, flushing and joint pain are the common side effects seen in the patients. If you see symptoms like swelling of ankles,fainting, weight gain, shortness of breath, fast heartbeat, weakness tell your doctor about this problems. This drug can effects on sperm production and also affect your ability to become father. The allergic reaction of Bosentan is rare.

PRECAUTION: Tell your doctor if you have allergic reaction towards the Bosentan.

Talk with your doctor if you have other disease like liver or kidney problems. This rug cause dizziness so kindly avoid driving and heavy exercise. Consumption of alcohol or cannabis can make you dizzier so kindly avoid it while taking the medicament. If you must not be taken in pregnancy because it can harms the unborn baby.

CDSCO APPROVAL: Bosentan (as monohydrate)Tablets 62.5mg/125mg approved by CDSCO in Indian in 23.06.2009.

FORMULATIONS AVAILABLE IN MARKET: Bosentan 62.5mg tablets

Bosentan 125mg tablets

Note: Product protected by valid patents are not offered for sale in countries where such patents are stil lvalid and its liability is at Buyers Risk

REFERENCES:

www.webmd.com

https://pubchem.ncbi.nlm.nih.gov

https://go.drugbank.com

https://cdscoonline.gov.in

https://www.wikipedia.org/

https://www.drugs.com

https://www.zaubacorp.com

https://www.practo.com/consult

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