Tizanidine Hcl

Tizanidine used in treatment of spinal code injury or multiple sclerosis. Tizanidine is a class ofdrug called skeletal muscle relaxants. Tizanidine works by slowing action inthe brain and nervous system.

• SYNONYMS: Tizanidin,Tizanidina, Tizanidine, Tizanidinum
• IUPAC NAME: 5-chloro-N-(4, 5-dihydro-1H-imidazol-2-yl)-2, 1, 3-benzothiadiazol-4-amine
• CAS NO: 51322-75-9
• FORMULA: C9H8ClN5S
• MOLECULAR MASS:253.71 g/mol                                                                                                                                                                                                                
  

STORAGE OF TIZANIDINE: Store at room temperature (15-30 degree C). Keep away from children and pets. Keep away from moisture and direct light. Do not freeze and do not store in bathroom or any humidly place.

APPLICATIONS OF TIZANIDINE: Tizanidine isused to control muscle spasms. This drug also used for treatment of multiplesclerosis, spinal cord injury, or muscle spasticity. Mainly used in treatment of brain or spinal cord injuries

HOW TO USE: Tizanidine is taken by mouth. In one day, you can take Tizanidine medicine up to 3 times. Take Tizanidine with or without food, but take it the same way each time for better result.

HOW TIZANIDINE WORKS: Tizanidine act as a muscle relaxant by blocking the nerve impulse

CONTRAINDICATIONS OF TIZANIDINE: Do not take Tizanidine if you have Hepatic disease and Psychosis. Kindy avoid Tizanidine if you have any Hypotension and renal failure. Do not share your medication with other person. Take your doctors recommendation if any adverse reactions appear while taking the treatment of Tizanidine.

PHARMACOKINETICS OF TIZANIDINE: Absorption is approximately 40% when you take Tizanidine by oral administration. Tizanidine half-life is about 150 minutes. Approximately 95% of an administered dose is metabolized. Tizanidine has peak plasma concentrations occurringn    1 hour after dosing. The major excretory route of Tizanidine is being via the kidneys.

SIDE EFFECTS OF TIZANIDINE: The most common side effect  of Tizanidine is dizziness, drowsiness, weakness, nervousness, hallucinations and depression. Other side effects like vomiting, dry mouth, constipation, diarrhea, stomach pain,heartburn, increased muscle spasms are also seen in patients. The very serious side effects to this  medicine are rare. But if you notice any kind of allergy like rash or itching, get medical help from your doctor.

PRECAUTIONS: Before using this medicine tell your doctor about your medical history especially if you are an allergic to Tizanidine. Tizanidine may make you dizzy and drowsy so kindly avoid taking alcohol during the dose o fthis medicine and avoid driving. Tizanidine contain inactive ingredient which can cause some allergic problem and other problems. Discuss with your doctor before breast-feeding. Because it is unknown if drug passes into breast. During the pregnancy kindly avoid Tizanidine or consult with your doctor.

CDSCO APPROVAL: Tizanidine hcl tablets are approved by CDSCO in India in 22.12.1993

Mefenamic acid + Tizanidine tablets are approved by CDSCO in India in 12.07.2002

Aceclofenac 100mg + Tizanidine 2mg film coated tablets are approved by CDSCO in India in 23.02.2009

FORMULATION AVAILABLE IN MARKET:

• Tizanidine 2 MG tablets
• Tizanidine 4 MG tablets
• Ibuprofen 400 MG+Tizanidine 2 MG tablets
• Nimesulide 100 MG+Tizanidine 2 MG tablets
• Diclofenac 50 MG+Serratiopeptidase 10 MG+Tizanidine 2 MGtablets
• Nimesulide 200 MG+Tizanidine 2 MG tablets
• Diclofenac 50 MG+Paracetamol 325 MG+Tizanidine 2 MG tablets
• Diclofenac 50 MG+Nimesulide 100 MG+Tizanidine 2 MG tablets
• Mefenamic Acid 500 MG+Tizanidine 2 MG tablet
• Tizanidine HCl tablets
• Mefenamic acid + Tizanidine tablets
• Aceclofenac 100mg + Tizanidine 2mg film coated tablets

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