TERBINAFINE

Product Description

Niksan Pharmaceuticaland theNiksan group companies are the world’s top most leading pharmaceuticalcompanies in the exporting, supplying and manufacturing Terbinafine API and also the finished pharmaceutical products ofTerbinafine like Terbinafine tablets and Terbinafine formulations. Niksan Pharmaceutical’sTerbinafine product is appreciated widely by our group companies and by thecustomers all around the world.

NiksanPharmaceutical is one of the most leading distributor, supplier, exporter andmanufacturer of Terbinafine products.

Niksan Pharmaceuticalprovides Terbinafine API in all over Indianstates like Delhi, Tamil Nadu, Odisha, Maharashtra, West Bengal, Uttar Pradesh,Gujarat, Madhya Pradesh, Haryana, Telangana, Bihar, Karnataka, Kerala, Punjab,Rajasthan, Andhra Pradesh in huge quantity.

Niksanpharmaceutical also manufacturing, trading, supplying and exporting Terbinafine API and Finishedformulations in countries of Nepal, Jamaica, Trinidad & Tobago, Tanzania,Netherlands, New Zealand, Kenya, UK, USA, Puerto Rico, Hong Kong, Pakistan,Belgium, Nigeria, Lebanon, Bangladesh, Tunisia, Canada, Australia, Latvia,Morocco, UAE, Algeria, Ireland, France, Israel, Philippines, Taiwan etc.

Terbinafine is ananti-fungal medicine that fights again fungus.

Terbinafine is used tomany fungal infections like fungal nail infections, ringworm, and pityriasis versicolor.

Terbinafine is an ally amine derivative which is take action againstdermatophytosis and other filamentous fungi.

SYNONYMS: Terbinafina,Terbinafine, Terbinafinum

IUPAC NAME: [(2E)-6,6-dimethylhept-2-en-4-yn-1-yl](methyl)[(naphthalen-1-yl)methyl]amine

CAS NO: 91161-71-6

FORMULA: C₂₁H₂₅N  

MOLECULARMASS: 291.43 g/mol

STORAGE OF TERBINAFINE: Store itin cool& dry place. Terbinafine is light sensitive drug so keep away fromlight and also put it in the light resistance container.

APPLICATIONSOF TERBINAFINE: Terbinafine is used to treatment of fingernail or toenail fungal infection.This medicine stopping the growth of fungus so this drug belongs to class ofantifungal.

HOW TO USE: Apply theTerbinafine solution in enough amounts to cover the affected skin areas. Do notcontact this medicine with nose, eyes, mouth, and other mucous membrane. Takethis tablet once daily for 6 weeks to protection against fingernail infectionand 12 weeks to protection against toenail infection. 

HOWTERBINAFINE WORKS: Terbinafine kills fungal cells. It makes holes in the cellmembrane of fungal cells and by that it will treats the fungal infection.

CONTRAINDICATIONSOF TERBINAFINE: Kindly avoid Terbinafine if you have chronic or active liverdisease. Do not take this medicine if you have allergic to Terbinafine in yourpast history.

PHARMACOKINETICSOF TERBINAFINE: 70% Terbinafine is absorbed by oral administration. Half-life ofTerbinafine is 36 hours. Peak Plasma Concentration of Terbinafine is 25%. 80%Terbinafine excreted by urine.

SIDE EFFECTSOF TERBINAFINE: Most common side effect of Terbinafine is Gastrointestinalproblems like diarrhoea,dyspepsia, gastritis, cholestasis, flatulence, altered stoolcolour, constipation, nausea, fullness, abdominal pain, indigestion,abdominal muscular pain etc. Other side effects are observed like headache,dizziness, vertigo and more skin problem like rashes, skin irritation, itchingetc. Sometimes this medicine cause Psychological problemslike depression, anxiety, insomnia, increased orunusual dream activity and malaise.

PRECAUTIONS: Before using the medication of Terbinafine share your medical history with your doctor orpharmacist. Dry your body properly after bathing if you use tube of Terbinafinefor ringworm. Stop taking this medicine if the infection or skin irritation isincrease. Avoid too much heat and humidity if possible.

CDSCO APPROVAL: Terbinafinetab/cream approved by CDSCO in India in 29.03.1995

Mometasonefuroate + Terbinafine HCl cream approved by CDSCO in India in 16.01.2002

FORMULATION AVAILABLE IN MARKET:

Terbinafine tablets

Terbinafine cream

Terbinafine 1 %W/W cream

Terbinafine 1 %W/V cream

Terbinafine 250 MG tablet s

Terbinafine 500 MG tablet s

Itraconazole 1 %W/W +Terbinafine 1 %W/W cream

Luliconazole 1 %W/W +Terbinafine 1 %W/W cream

Beclometasone 0.025 %W/W +Terbinafine 1 %W/W cream

Salicylic Acid 3 %W/W +Terbinafine 1 %W/W cream

Clobetasol propionate 0.05 %W/W+ Terbinafine 1 %W/W cream

Itraconazole 100 MG +Terbinafine 250 MG tablets

Mometasone furoate 0.1 %W/W +Terbinafine 1 %W/W cream

Mometasone Furoate 0.1 %W/V +Terbinafine 1 %W/V gel

Mometasone furoate + Terbinafine HCl cream

Note: Productprotected by valid patents are not offered for sale in countries where suchpatents are still valid and its liability is at Buyers Risk.

REFERENCES:

www.webmd.com

https://pubchem.ncbi.nlm.nih.gov

https://go.drugbank.com

https://cdscoonline.gov.in

https://www.wikipedia.org/

https://www.drugs.com

https://www.zaubacorp.com

https://www.practo.com/consult