Lifenacin belongs to the antimuscarinic drug class. It is used to treat overactive bladder. Solifenacin relaxes the bladder muscles to control urination. This medicine prevents urine from leaking. Solifenacin works by blocking M2 and M3 uscarinic receptors, thereby treating overactive bladder and reducing urine frequency and urinary urgency. Solifenacin 10mg tablet may be taken with or without food once a day. Consult your doctor and read the label for instructions.
Solifenacin comes in the drug class called anti muscarinics. Solifenacin medicine used in the treatment of overactive bladder. Solifenacin helps to control the urination by relaxing the bladder muscles. Solifenacin medicine helps to reduce leaking of urine.
SYNONYMS: Solifenacin, Solifenacina.
IUPACNAME: (3R)-1-azabicyclo [2.2.2] octan-3-yl (1S)-1-phenyl-1, 2, 3, 4-tetrahydroisoquinoline-2-carboxylate
CAS NO: 242478-38-2
MOLECULAR MASS: 362.473gm/mol
STORAGE CONDITION: Store in cool and dry place. Do not place medication in bathroom or any humid place. Place medication away from sun light. Keep away from children and pets.
HOW TO USE: Take Solifenacin 10mg tablet by mouth with or without food one time per day. Follow your doctors order, and also read the instruction on the label.
HOW SOLIFENACIN WORKS: Solifenacin blocks the M2 and M3 uscarinic receptors and by this Solifenacin treats the overactive bladder and helps to reduce urine frequency and urinary urgency.
PHARMACOKINETICS OF SOLIFENACIN: Solifenacin will nor absorb in stomach but well absorbed in duodenum, jejunum and in ileum. Solifenacin takes 3-8 hours to reach the peak plasma concentration. And the bioavailability of Solifenacin is 88%. The half-life of Solifenacin is between 33-85 hours. 697.8% of Solifenacin is recovered in urine and the remaining residues recovered in feces.
SIDE EFFECTS OF SOLIFENACIN: The common side effects like constipation, stomach upset, drowsiness, weakness, tiredness,headache, dry eyes, and dry mouth are shown in the patients. Tell your doctor right away if you have any side effects like stomach pain, kidney infection,constipation for 2 or more days, pain in urination, mood changes. There are some rare side effects like rash, itching, swelling also seen in some patients.
PRECAUTIONS: Before taking the medication tell your doctor if you are allergic to the Solifenacin or its residues. This drug cause drowsiness and blur vision so does not take alcohol or marijuana. Because of the drug cause dizziness or blur vision do not drive vehicle or do any heavy exercise after taking medication. To prevent constipation drink more amount of water, and eat fibres. To prevent the dry mouth, eat candy, or suck ice chips and drink water.
CDSCO APPROVAL: Solifenacin Succinate Tablet (5mg/10mg) approved by CDSCO in India in 06.07.2006.
FORMULATION AVAILABLE INMARKET:
Solifenacin Succinate 5 mg tablets
Solifenacin Succinate 10 mg tablets
Solifenacin Succinate 5mg +Mirabegron 50 mg tablets
Solifenacin Succinate 5mg +Mirabegron 25 mg tablets
Alfuzocin 10 mg + Solifenacin Succinate 5mg tablets
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