Celecoxib

Product Description

NiksanPharmaceutical is one of the leading Manufacturer, Exporter,Distributor, andSupplier of Celecoxibin Ankleshwar, Gujarat,India. To understand the largest accomplishment of clients, we present theseproducts at very realistic price ranges. Niksan Pharmaceutical and Niksan groupcompanies are nowadays one of the largest manufacturers and exporters of CelecoxibAPI and also finished formulations. 

NiksanPharmaceutical and Niksan group companiesare the very well-known manufacturers, suppliers and distributors of Celecoxibproducts. 

Niksan Pharmaceutical providesAPI and finished formulation of Celecoxib in manyIndian states like Himachal Pradesh, Andhra Pradesh, Tamil Nadu, Telangana,Kerala, Karnataka, Gujarat, Jammu & Kashmir, Chandigarh, Punjab,Uttarakhand, Chhattisgarh, Haryana, Maharashtra, Odisha, Uttar Pradesh, Delhi,Rajasthan, Madhya Pradesh, West Bengal, Bihar, Assam and many other Indianstates.

NiksanPharmaceutical are manufacturing and exporting very large quantity of Celecoxib in countries like Zimbabwe,Peru, Philippines, Chile, Dominican Republic, Mexico,New Zealand, Guatemala, Honduras, Costa Rica,SriLanka, Ghana, Qatar, Ecuador,Vietnam, ElSalvador, Colombia, Bolivia, Australia,Hong KongUnited Arab Emirates, Panama, Kenya,Singapore, Jordan,Canada, Malaysia,Iraq, Iran,United States, Nigeria, Pakistan, Romania, SouthKorea, Saudi Arabia, Germany, Netherlands,Taiwan, Spain,Thailand, Switzerland,South Africa, Portugal, Israel, Ireland, Algeria,Egypt, Belgium,Sweden, UnitedKingdom, Venezuela, Finland, Indonesia,Austria, Italy,China, Argentina,France,Brazil, Japan, Poland and many othercountries. 

Celecoxib belongs to the non-steroidalanti-inflammatory drug. Celecoxib generally used to treat the pain in the gout,rheumatoid arthritis, joint pain, osteoarthritis, inflammation in joints andkidney failure. 

Celecoxib is cox- selective inhibitor. 

SYNONYMS: Celecoxib, Célécoxib, Celecoxibum. 

IUPAC NAME: 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide 

CAS NO: 169590-42-5  

FORMULA: C17H14F3N3O2S 

MOLECULAR MASS: 381.37 g/mol

STORAGE CONDITION: Store in room temperature,away from heat and direct light. Do not store in kitchen or bathroom. Keep awayfrom children and pet.  

HOW TO USE: Take medication once or twicea day by orally with water. To avoid the chance of stomach pain or stomachupset take medication with food.  Takeyour doctor’s advice if you have any confusion. 

HOW CELECOXIB WORKS: Celecoxib give relief in,rheumatoid arthritis, joint pain, osteoarthritis, inflammation in joints, painin the gout, by inhibiting the actions of COX-2 enzyme. Celecoxib also used totreat swelling in joints 

PHARMACOKINETICS OF CELECOXIB: Celecoxib rapidly absorbedin GI track after oral administration. It takes 1-2 hourstoreach the max plasmaconcentration. Almost 97% of Celecoxib binds with albumin in body. The halflife of Celecoxib is 11 hours in the normal person. The primary elimination ofCelecoxib done by hepatic metabolism, 57% of Celecoxib eliminated by faces andthe remaining residues are excreted by urination. 

SIDE EFFECTS OF CELECOXIB: Normally gas and stomachupset are the side effects seen in patients. The several side effects likeheadache, swelling of calf, kidney problems, problem in urination, yellow eyes,stomach pain. Get medical attention if you see side effects like black urine,swelling of limbs, stomach problem or yellowing of skin/eyes. There are somerare side effects like itching, swelling, dizziness, irritation, trouble inbreathing also seen in patients. 

PRECAUTIONS: Kindly tell you doctor if youhave allergic reactions towards the Celecoxib medication. Do not take Celecoxibwith the aspirin and other NSAID products.Kindly avoid taking Celecoxib medicine if you have problemlike liver problem, heart problem, kidney problem, stroke, blood pressureproblem, ulcers. Take your doctor’s advice if you are pregnant or in lactationperiod. Use of alcohol or tobacco may cause stomach bleeding.

CDSCO APPROVAL: Celecoxib capsule approved by CDSCO in Indianin 22-02-2000, Celecoxib 100/200mg +Diacerein 50/50mg approved by CDSCO inIndian in 19.07.2010,

Celecoxibcapsule approved by CDSCO in Indian in 15.02.2002,

CelecoxibMouth Dissolving Tablet 50/100/200 mg approved by CDSCO in Indian in25.02.2010,

Celecoxibinjection approved by CDSCO in Indian in 2004-October, Celecoxib injectionapproved by CDSCO in Indian in 27.10.2004.

FORMULATION AVAILABLE IN MARKET:

Celecoxib100mg +Diacerein 50mg capsules

Celecoxib200mg +Diacerein 50mg capsules

Celecoxib50 mg Mouth Dissolving Tablets

Celecoxib100 mg Mouth Dissolving Tablets

Celecoxib200 mg Mouth Dissolving Tablets

Celecoxibinjection

Celecoxib200mg capsules

Celecoxib100mg capsules

Note: Product protected by validpatents are not offered for sale in countries where such patents are stillvalid and its liability is at Buyers Risk

REFERENCES: 

www.webmd.com

https://pubchem.ncbi.nlm.nih.gov

https://go.drugbank.com

https://cdscoonline.gov.in

https://www.wikipedia.org/

https://www.drugs.com

https://www.zaubacorp.com

https://www.practo.com/consult