Niksan Pharmaceutical is the largest manufacturer, Exporter sandsupplier of Benidipine. Benidipine is a one of themost famous medicine invented by Japanese. Benidipine is first Launch in Indiaby Niksan Pharmaceutical with manufacturing from first step. Nowadays NiksanPharmaceutical is one of the leading manufacturer and exporter whomanufacturing Benidipine as well as Intermediates of Benidipine.
Niksan Pharmaceutical and Niksan group companies are exporters,suppliers and manufacturers of the API and also Benidipine formulations in manycountries for many years. Niksan pharmaceutical currently export Benidipine APIand Formulation to countries like Japan, Myanmar, Shrilanka, UAE, Kenya, Vietnam, Australia, SaudiArabia, United States, United Kingdom, China, and Korea and also in someEuropean countries.
Niksan is an Indian based pharmaceutical company so it alsosupplies and manufactures the Benidipine to all Indian states like Gujarat,Maharashtra, Punjab, Delhi, Tamilnadu, Goa, Uttar Pradesh, Karnataka, Jammu& Kashmir, West Bengal, Assam, Rajasthan, and Hyderabad Etc.
Benidipine is a new generation triple L-, T-, and N-type calcium channel blocker used as antihypertensive agent.
Benidipine is a calcium channel blocker class ofmedicine.it is widely use in the treatment of chest pain and also given to thepatient who is suffering from hypertension. Benidipine also use to reduce theblood pressure level.
IUPAC NAME: 3-(3R)-1-benzylpiperidin-3-yl 5-methyl (4R)-2, 6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3, 5-dicarboxylate
CAS NO: 105979-17-7
FORMULA: C28H31N3O6
MOLECULAR MASS: 505.571 g/mol
STORAGE: Store in room temperature.
Place it in cool and dry place.
APPLICATION: Benidipine is mostly use as antihypertensiveagent. It also used in the Angina pectoris. The tablet is given when the chestpain occurs.
HOW TO USE: Benidipine tablet taken orally with food. It is given 2-4mg daily.
When chest pain occurs take 4mg 2 times per day.
CONTRAINDICATIONS: Do not take Benidipine medicine in pregnancyand lactation period. Take your doctorâs advice before taking medicine.
PHARMACOKINETICS: Benidipine israpidly absorbed after oral administration reaching a maximum concentrationwithin 2 hours. Benidipine completely metabolize in liver. Excretion is done byfaces; most of the drug is excreted by bile.
SIDE EFFECTS: Benidipine have sideeffects like hypersensitivity (rash, itching), sometimes musculoskeletaleffects like redness, stiffing in shoulders are also shown. Benidipine alsogive effects on heart like chest pain, hot flushes.
There are also some minorside effects are also there like nausea, vomiting, headache, insomnia,constipation. If it goes worse take advice to your doctor.
PRECAUTIONS: If you have liver problems kindly avoidtaking the medicine. Benidipine causes blurred vision and drowsiness sokindly avoids driving, operating machinery and performing any hazardousactivity. Biperiden cause drowsiness so kindly avoid alcohol when takenmedicine.
CDSCO APPROVAL: Benidipine Hydrochloride tablets areapproved by CDSCO in India in 12.08.1996.
FORMULATIONS IN MARKET:
Benidipine Hydrochloride tablets 4mg (film coated)
Benidipine Hydrochloride tablets 8mg (film coated)
Benidipine 4 MG tablets
Benidipine 8 MG tablets
Benidipine 4 MG +Telmisartan 80 MG tablets
Benidipine 4 MG +Telmisartan 40 MG tablets
Benidipine 4 MG +Metoprolol 25 MG tablet
Benidipine 4 MG +Metoprolol 50 MG tablets
Atenolol 50 MG +Benidipine 4 MG tablets
Benidipine 4 MG + Chlorthalidone 12.5 MG tablets
Benidipine 4 MG + Chlorthalidone 6.25 MG tablets
Benidipine 4 MG + Chlorthalidone 12.5 MG +Telmisartan 40 MG tablets
Benidipine 4 MG +Chlorthalidone 6.25 MG +Telmisartan 40 MG tablets
Note: Product protected by valid patents are notoffered for sale in countries where such patents are still valid and itsliability is at Buyers Risk
REFERENCES:
www.webmd.com
https://pubchem.ncbi.nlm.nih.gov
https://go.drugbank.com
https://cdscoonline.gov.in
https://www.wikipedia.org/
https://www.drugs.com
https://www.zaubacorp.com
https://www.practo.com/consult
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