Product Description

Niksan Pharmaceutical is the largest manufacturer, Exporter and supplier of Benidipine. Benidipine is a one of the most famous medicine invented by Japanese. Benidipine is first Launch in India by Niksan Pharmaceutical with manufacturing from first step.Nowadays Niksan Pharmaceutical is one of the leading manufacturer and exporter who manufacturing Benidipine as well as Intermediates of Benidipine. 

Niksan Pharmaceutical and Niksan group companies are exporter,supplier  and manufacturers of the API and also Benidipine formulations in many countries for many years. Niksan pharmaceutical currently export Benidipine API and Formulation to countries like Japan, Myanmar, Shrilanka, UAE, Kenya, Vietnam, Australia, Saudi Arabia, United States, United Kingdom, China, and Korea and also in some European countries. 

Niksan is an Indian based pharmaceutical company so it alsosupplies and manufactures the Benidipine to all Indian states like Gujarat,Maharashtra, Punjab, Delhi, Tamilnadu, Goa, Uttar Pradesh, Karnataka, Jammu& Kashmir, West Bengal, Assam, Rajasthan, and Hyderabad Etc. 

Benidipine is a new generation triple L-,T-, and N- type calcium channel blocker used as anti hypertensive agent.

Benidipine is a calcium channel blocker class of medicine.it is widely use in the treatment of chest pain and also given to the patient who is suffering from hypertension. Benidipine also use to reduce the blood pressure level. 

IUPAC NAME: 3-(3R)-1-benzylpiperidin-3-yl 5-methyl (4R)-2, 6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3, 5-dicarboxylate 

CAS NO: 105979-17-7 

FORMULA: C₂₈H₃₁N₃O₆ 

MOLECULAR MASS: 505.571 g/mol 

STORAGE: Store in room temperature.Place it in cool and dry place. 

APPLICATION: Benidipine is mostly use as antihypertensive agent. It also used in the Angina pectoris. The tablet is given when the chest pain occurs. 

HOW TO USE: Benidipine tablet taken orally with food. It is given 2-4mg daily.When chest pain occurs take 4mg 2 times per day. 

CONTRAINDICATIONS: Do not take Benidipine medicine in pregnancy and lactation period. Take your doctor's advice before taking medicine. 

PHARMACOKINETICS: Benidipine is rapidly absorbed after oral administration reaching a maximum concentration within 2 hours. Benidipine completely metabolize in liver. Excretion is done by faces; most of the drug is excreted by bile. 

SIDE EFFECTS: Benidipine have side effects like hypersensitivity (rash, itching), sometimes musculoskeletal effects like redness, stiffing in shoulders are also shown. Benidipine also give effects on heart like chest pain, hot flushes. There are also some minor side effects are also there like nausea, vomiting, headache, insomnia,constipation. If it goes worse take advice to your doctor. 

PRECAUTIONS: If you have liver problems kindly avoid taking the medicine. Benidipine causes blurred vision and drowsiness so kindly avoids driving, operating machinery and performing any hazardous activity. Biperiden cause drowsiness so kindly avoid alcohol when taken medicine. 

CDSCO APPROVAL: Benidipine Hydrochloride tablets are approved by CDSCO in India in 12.08.1996. 

FORMULATIONS IN MARKET:

Benidipine Hydrochloride tablets 4mg (film coated)

Benidipine Hydrochloride tablets 8mg (film coated)

Benidipine 4 MG tablets

Benidipine 8 MG tablets

Benidipine 4 MG +Telmisartan 80 MG tablets

Benidipine 4 MG +Telmisartan 40 MG tablets

Benidipine 4 MG +Metoprolol 25 MG tablet

Benidipine 4 MG +Metoprolol 50 MG tablets

Atenolol 50 MG +Benidipine 4 MG tablets

Benidipine 4 MG + Chlorthalidone 12.5 MG tablets

Benidipine 4 MG + Chlorthalidone 6.25 MG tablets

Benidipine 4 MG + Chlorthalidone 12.5 MG +Telmisartan 40 MG tablets

Benidipine 4 MG +Chlorthalidone 6.25 MG +Telmisartan 40 MG tablets 

Note: Product protected by valid patents are not offered for sale in countries where such patents are still valid and its liability is at Buyers Risk 

REFERENCES:

www.webmd.com

https://pubchem.ncbi.nlm.nih.gov

https://go.drugbank.com 

https://cdscoonline.gov.in 

https://www.wikipedia.org/

https://www.drugs.com

https://www.zaubacorp.com

https://www.practo.com/consult