SEVELAMER CARBONATE

Product Description

is one of the biggest manufacturer, supplier, exporter and trader ofthe SEVELAMER CARBONATEfinished formulations moreover SEVELAMER CARBONATE API. Niksan Pharmaceutical is the huge manufacturer, exporter andsupplier of SEVELAMER CARBONATEAPI and formulation situated in Ankleshwar, Gujarat,India.

NiksanPharmaceutical is the suppliers, manufacturer, exporters and trader of
SEVELAMER CARBONATE inthedomestic level as well as the international market.

 

Niksan Pharmaceutical is anIndian based pharmaceutical company so it also supplies and manufactures the SEVELAMER CARBONATE to allIndian states like Gujarat, Maharashtra, Punjab, Delhi, Tamilnadu, Goa, UttarPradesh, Karnataka, Jammu & Kashmir, West Bengal, Assam, Rajasthan,Hyderabad, Karnataka, Kerala, Madhya Pradesh, Manipur,Meghalaya, Mizoram, Nagaland, Orissa, Punjab and Haryana.  

NiksanPharmaceutical and Niksan group companies are exporters, suppliers andmanufacturers of the API and also SEVELAMER CARBONATE formulations in many countries for manyyears. Niksan pharmaceutical currently exports SEVELAMER CARBONATE API and Formulation to countries like NewZealand, Jordan, Belgium, United Kingdom, Australia, Italy, Ireland, Hong Kong,Morocco,, Portugal, France, South Africa, Philippines, Malaysia, Singapore,Israel, Greece, Saudi Arabia, Egypt, Taiwan, Netherlands, South Korea,Switzerland, Algeria, Pakistan, Canada, Vietnam, United States, Germany, Braziland many other countries.

 

SEVELAMERCARBONATE isa phosphate binder used to treat hyperphosphatemia. It’s medication used to control the levels of the nutrient, phosphate,in the blood.

 

SYNONYSMS:Renvela, Sevelamer, Sevelamero, Sevelamerum

 

IUPAC NAME: poly(allylamine-co-N,N'-diallyl-1,3-diamino-2-hydroxypropane)carbonate salt

 

CAS NO:845273-93-0

 

FORMULA: C7H14ClNO4

 

MOLECULAR MASS:  211.64 g/mol

 

STORAGE CONDITIONS: No specialstorage conditions

 

HOW TO USE:It’s comes as atablet and as a powder for suspension to take by mouth. It is usuallytaken three times a day with meals. Follow the directions on your prescriptionlabel carefully, and ask your doctor or pharmacist to explain any part you donot understand.

 

HOW SEVELAMERCARBONATE WORKS: Sevelamer carbonate works by binding to phosphate in thegastrointestinal tract, preventing its absorption into thebloodstream. This helps to lower high phosphorus levels, or hyperphosphatemia, in peoplewith chronic kidney disease whoare on dialysis. It's a phosphate binder thatessentially acts like a sponge for phosphate in the gut. 

 

PHARMACOKINETICSOF SEVELAMER CARBONATE: Sevelamer carbonate, a phosphate binder used in managinghyperphosphatemia in patients with chronic kidney disease, is not absorbedsystemically and therefore has no conventional pharmacokinetic propertieslike absorption, distribution, metabolism, and elimination. It actslocally within the gastrointestinal tract. 

 

SIDE EFFECTS OF SEVELAMER CARBONATE:The normalside effects caused by SEVELAMER CARBONATE are diarrhea, vomiting, nausea,stomach pain, gas, heartburn, new or worsening constipation.

 

PRECAUTIONS: Tell yourdoctor if you are allergic to the medicine. Stop taking sevelamer and get help rightaway if you have any swallowing problems. Severe Constipation. Sevelamer cancause severe constipation, which may lead to further gastrointestinal (GI)issues, such as inflammation, bleeding, sores (ulcers), blockage (obstruction),or a hole in the intestine.

 

CDSCOAPPROVAL:

Sevelamer Carbonate 400mg/800mg tablets &sachet 400mg/800mg (28.04.08)

Sevelamer Carbonate (Additional Indication)(26.11.09)

 

FORMULATIONSAVAILABLE IN MARKET:

SEVELAMER CARBONATE 400 MG tablets

SEVELAMER CARBONATE 800 MG tablets

SEVELAMER CARBONATE 0.8g and 2.4gPowder For Oral Suspension

 

Note: Productprotected by valid patents are not offered for sale in countries where suchpatents are still valid and its liability is at Buyers Risk

 

REFERENCES:

www.webmd.com

https://pubchem.ncbi.nlm.nih.gov

https://go.drugbank.com 

https://cdscoonline.gov.in 

https://www.wikipedia.org/

https://www.drugs.com

https://www.zaubacorp.com

https://www.practo.com/consult