is leading manufacturer and distributer of the Primidone among the other countries. NiksanPharmaceutical is one of the major the supplier, distributer, exporter andmanufacturer of the Primidone API andfinished formulations in Ankleshwar, Gujarat, India. The products of NiksanPharmaceutical and Niksan group companies are widely appreciated by the clientsand other companies.
NiksanPharmaceutical is the supplier, manufacturer, exporter and trader of Primidone in thedomestic level as well as the international market.
NiksanPharmaceutical provides PrimidoneAPI in allover Indian states like Jammu & Kashmir, Himachal Pradesh, Uttarakhand,Punjab, Kerala, Chandigarh, Chhattisgarh, Andhra Pradesh, Rajasthan, Meghalaya, Mizoram,Nagaland, Orissa,, Dadra and NagarHaveli, Goa, Gujarat, Jharkhand, West Bengal, Karnataka, Kerala, Madhya Pradeshetc.
NiksanPharmaceutical also provides Primidone API and finished formulations in all othercountries of the world like Germany, Switzerland, Poland, Latvia, Egypt,Lithuania, Estonia, Ukraine, Moldova, Russia, United States, Austria, Belarus,Serbia, India, Spain, Slovenia, Nigeria, Croatia, South Africa, Kazakhstan,Italy, Romania, Bulgaria, Portugal, South Korea, Greece, Philippines, Belgium,Saudi Arabia, Turkey, Japan etc.
Primidone is one typeof antiepilepticmedication developed to treat seizures,commonly for partial and generalized seizures.
SYNONYMS: 2-deoxyphenobarbital, Primidon, Primidona, Primidone, Primidonum
IUPAC NAME: 5-ethyl-5-phenyl-1,3-diazinane-4,6-dione
CAS NO: 125-33-7
STORAGE OF PRIMIDONE : Store the medicine in a closed container at roomtemperature, away from heat, moisture, and direct light. Keep from freezing.
APPLICATIONSOF PRIMIDONE:Primidone is used alone or with other medications to control certain types of seizures.Primidone is in a class of medications called anticonvulsants. It works bydecreasing abnormal electrical activity in the brain.
Primidone comes as a tablet to take by mouth. It is usually taken 3 to 4 times a day.
HOW PRIMIDONE WORKS: Primidone is used alone or with other medications tocontrol certain types of seizures. Primidone is in a class of medicationscalled anticonvulsants. It works by decreasingabnormal electrical activity in the brain.
CONTRAINDICATIONSOF PRIMIDONE: Primidone is contraindicated in patients who are known to behypersensitive to barbituric acid derivatives. Contraindications to primidoneinclude patients with a history of porphyria. By inducing the enzymesresponsible for porphyrin synthesis, barbiturates may worsen acute porphyria.
PHARMACOKINETICSOF PRIMIDONE: Primidone is wellabsorbed and distributed throughout the body.Maximum plasma concentration is reached in about 2 h after administration of a250 mg tablet. Primidone is metabolized in the liver to active metabolites:phenobarbital and phenylethylmalonic acid (PEMA).
SIDE EFFECTS OF PRIMIDONE: The mostcommon side effect of primidone therapy is sedation and drowsiness.Ataxia, diplopia, and nystagmus occur at the initiation of treatment. Otheradverse reactions include dizziness, vertigo, epigastric pain, megaloblasticanemia, respiratory depression, polyuria, skin rash, facial edema.
PRECAUTIONS: Check with your doctor before taking any of the above while you areusing this medicine. Primidone may cause some people to become dizzy,lightheaded, drowsy, or less alert than they are normally. Even if taken atbedtime, it may cause some people to feel drowsy or less alert on arising.
Primidonetablet 50mg are approved by CDSCO in India in15.04.2019
FORMULATION AVAILABLE IN MARKET:
Primidone 12.5mg tablet
Primidone 25mg tablet
Primidone 50mg tablet
Primidone 100mg tablet
Primidone 250mg tablet
Note: Productprotected by valid patents are not offered for sale in countries where suchpatents are still valid and its liability is at Buyers Risk