PRIMIDONE

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Product Details:

Melting Point 281C
HS Code 2933.59
EINECS No 204-737-0
Solubility practically insoluble in water (1/2000), slightly soluble in alcohol (1/200), and soluble in alkaline solutions
Shelf Life 3 Years
Heavy Metal (%) Lead
Storage Room Temperature
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PRIMIDONE Price And Quantity

Minimum Order Quantity 1 Kilograms

PRIMIDONE Product Specifications

EINECS No 204-737-0
HS Code 2933.59
Melting Point 281C
Heavy Metal (%) Lead
Usage Primidone is one type of antiepileptic medication developed to treat seizures, commonly for partial and generalized seizures.
Medicine Name PRIMIDONE
CAS No 125-33-7
Shelf Life 3 Years
Solubility practically insoluble in water (1/2000), slightly soluble in alcohol (1/200), and soluble in alkaline solutions
Grade Medicine Grade
Structural Formula C12H14N2O2
Appearance White to Off-White Solid
Loss on Drying Not more than 0.5%
Chemical Name PRIMIDONE
Smell Other
Molecular Formula C12H14N2O2
Boiling point 520.7 C
Storage Room Temperature
Physical Form Powder
Molecular Weight 218.25 g/mol Grams (g)
Ph Level NA
Taste Other
Type Other
Particle Size 149.9 to 188.8 nm
Purity(%) 99 %

PRIMIDONE Trade Information

FOB Port INDIA
Supply Ability 100 Kilograms Per Month
Delivery Time 1 Days
Sample Available No
Packaging Details HDPE DRUM WITH TWO INNER LDPE LINNER
Main Domestic Market All India, South India, Central India, West India, North India, East India, Gujarat, Karnataka, Kerala, Lakshadweep, Mizoram, Meghalaya, Manipur, Andhra Pradesh, Bihar, Chandigarh, Daman and Diu, Goa, Jharkhand, Odisha, Punjab, Assam, Delhi, Dadra and Nagar Haveli, Andaman and Nicobar Islands, Arunachal Pradesh, Chhattisgarh, Haryana, Himachal Pradesh, Jammu and Kashmir, Madhya Pradesh, Maharashtra, Nagaland, Rajasthan, Sikkim, Tamil Nadu, Telangana, Tripura, Pondicherry, Uttar Pradesh, Uttarakhand, West Bengal
Certifications GMP, FDCA

Product Description

SYNONYMS: 2-deoxyphenobarbital, Primidon, Primidona, Primidone, Primidonum

IUPAC NAME: 5-ethyl-5-phenyl-1,3-diazinane-4,6-dione

CAS NO: 125-33-7

FORMULA: C₁₂H₁₄N₂O₂

MOLECULARMASS:218.25 g/mol

STORAGE OF PRIMIDONE : Store the medicine in a closed container at roomtemperature, away from heat, moisture, and direct light. Keep from freezing.

APPLICATIONSOF PRIMIDONE:Primidone is used alone or with other medications to control certain types of seizures.Primidone is in a class of medications called anticonvulsants. It works bydecreasing abnormal electrical activity in the brain.

It is usually taken 3 to 4 times a day.

PRIMIDONE WORKS: Primidone isused alone or with other medications to control certain types of seizures.Primidone is in a class of medications called anticonvulsants. It worksby decreasing abnormal electrical activity in thebrain.

PRIMIDONE: Primidone is contraindicated in patients who are known to behypersensitive to barbituric acid derivatives. Contraindications to primidoneinclude patients with a history of porphyria. By inducing the enzymesresponsible for porphyrin synthesis, barbiturates may worsen acute porphyria.

PHARMACOKINETICSOF PRIMIDONE: Primidone is well absorbed and distributed throughout the body. Maximum plasma concentration is reached in about 2 h afteradministration of a 250 mg tablet. Primidone is metabolized in the liver toactive metabolites: phenobarbital and phenylethylmalonic acid (PEMA).

SIDE EFFECTS OF PRIMIDONE: The most common sideeffect of primidone therapy is sedation and drowsiness. Ataxia, diplopia,and nystagmus occur at the initiation of treatment. Other adverse reactionsinclude dizziness, vertigo, epigastric pain, megaloblastic anemia, respiratorydepression, polyuria, skin rash, facial edema.

PRECAUTIONS: Check with your doctor before taking any of the above while you areusing this medicine. Primidone may cause some people to become dizzy,lightheaded, drowsy, or less alert than they are normally. Even if taken atbedtime, it may cause some people to feel drowsy or less alert on arising.

CDSCO APPROVAL:

Primidone tablet 50mg are approved by CDSCO in India in 15.04.2019

FORMULATION AVAILABLE IN MARKET:

Primidone12.5mg tablet

Primidone25mg tablet

Primidone50mg tablet

Primidone100mg tablet

Primidone250mg tablet

Note: Productprotected by valid patents are not offered for sale in countries where suchpatents are still valid and its liability is at Buyers Risk

REFERENCES:

www.webmd.com

https://pubchem.ncbi.nlm.nih.gov

https://go.drugbank.com

https://cdscoonline.gov.in

https://www.wikipedia.org/

https://www.drugs.com

https://www.zaubacorp.com

https://www.practo.com/consult

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