BIPERIDEN

Product Description

Niksan Pharmaceutical and the Niksan group companies are the worlds topmost leading pharmaceutical companies in the exporting, supplying andmanufacturing of the Biperiden APIand also the finished pharmaceutical products of Biperiden like Biperidentablets and Biperiden injections. Niksan pharmaceuticals Biperiden product isappreciated widely by our group companies and by the customers all around theworld.

Niksan Pharmaceutical is the supplier, manufacturer, supplier, andexporter sand trader in the domestic level as well as the international market.

Niksan Pharmaceutical provides BiperidenAPI in all over Indian states like Delhi, Tamil Nadu, Odisha, Maharashtra, WestBengal, Uttar Pradesh, Gujarat, Madhya Pradesh, Haryana, Telangana, Bihar,Karnataka, Kerala, Punjab, Rajasthan, Andhra Pradesh in huge quantity.

Niksan Pharmaceuticalalso manufacturing, trading, supplying and exporting  Biperiden API and Finished formulations incountries of Philippines, Germany, Taiwan, Lebanon, Iran, Ireland,  Israel, South Africa, Egypt, Austria, Switzerland, Turkey, Czechia, Greece,Poland, Mexico, Australia, Peru, United States, United Kingdom and many other states.

 

Biperiden belongs to the anticholinergic class of medicine.Mostly Biperiden is use in the treatment of Parkinson disease worldwide. Dosageforms like oral dosage form (Tablets) and parenteral dosage form (injections)are available in market under the brand name of Akineton.

 

IUPAC NAME: 1-{bicyclohept-5-en-2-yl}-1-phenyl-3-(piperidin-1-yl) propan-1-ol

 

CAS NO: 541-65-8

FORMULA: C₂₁H₂₉NO

MOLECULAR MASS: 311.46 g/mol

STORAGE: Store it in cool dryplace. Biperiden is light sensitive drug so keep away from light and also putit in the light resistance container.

APPLICATION: Biperiden is a most widely used asantiparkinson agent it is also use to treat stiffness, tremors, spasms, and poor musclecontrol of Parkinsons disease.

 

HOW TO USE: Biperiden is commonly taken with the fullglass of water. If taking Biperiden upsets your stomach, take medicine aftermeal. Maximum dose of Biperiden is 8 tablets (16 mg) per day. The parenteraldosage form must be required to given by medical practitioners or if you haveany confusion related to medicine kindly contact your doctor.

 

CONTRAINDICATIONS: Basically you cannot take the medicine ifyou have allergic reaction to Biperiden. If you have any bowel disease kindlyavoid the use of Biperiden.  

Tell your doctor ifyou have any kidney related disorders. Kindly share the information to doctorif you have any heart disease, epilepsy or ant seizure type disease.

It is also not knownwhether Biperiden passes into breast milk.so gently do not take Biperidenwithout first talking to your doctor if you are breast-feeding a baby.

 

PHARMACOKINETICS: Biperiden is well absorbed through the GItrack after oral administration. After the GI administration Biperiden goes toliver and then metabolise there. Although the metabolism of Biperiden is notwell known. Excretion of Biperiden is done by urination.

 

MAJOR AND MINOR SIDE EFFECTS OF BIPERIDEN: There are some minorside effects of Biperiden like eye pain, rash, seizures, dry mouth, upsetstomach like side effects  are commonlyshown in the patient. Some major side effects are also caused by using theBiperiden, but these are some rare side effects like blurred vision, difficultyin urinating, nervousness, hallucinations, fast and irregular heartbeats, andloss of consciousness.

 

PRECAUTIONS: Biperiden causes blurred vision anddrowsiness so kindly avoid driving, operating machinery and performing any hazardousactivity. Biperiden cause drowsiness so kindly avoid alcohol when takenmedicine. Try to stay in cool places because the threat of heat stroke.

 

TOXICITY: The over overdose of Biperiden cause seriousproblems like flushed Face, fever, dry mouth, fast or irregular heartbeat ,anxiety, hallucinations, Confusion, agitation, hyperactivity, loss ofconsciousness, and seizures.

 

CDSCO APPROVAL: Biperiden lactate formulation is approved byCDSCO in OCTOBER-1972.

Biperiden hydrochloride formulation is approved by CDSCO in JULY-1972.

 

FORMULATIONS IN MARKET:

 

Biperiden lactate injections

Biperiden hydrochloride 16 mg tablets

 

Note: Product protected by valid patents are notoffered for sale in countries where such patents are still valid and itsliability is at Buyers Risk

 

REFERENCES:

 www.webmd.com

https://pubchem.ncbi.nlm.nih.gov

https://go.drugbank.com 

https://cdscoonline.gov.in 

https://www.wikipedia.org/

https://www.drugs.com

https://www.zaubacorp.com

https://www.practo.com/consul

Key Features and Chemical Profile

Biperiden appears as a white to yellowish-white powder, ensuring consistency in formulation. Its chemical structure is denoted by C21H29NO, with a molecular weight of 311.46 g/mol. The powders 10-micron particle size ensures uniform distribution in medicinal applications. With a melting point of 270C and a pH range of 4.254.8, it maintains stability during storage and handling, making it an optimal choice for pharmaceutical preparations.


Usage and Benefits in Medicine

Biperiden is primarily used to help manage symptoms of Parkinsons disease, either as a single agent or in combination therapy. It acts by improving muscle control and reducing stiffness, thus enabling smoother and more controlled movement for patients. Pharmaceutical companies, distributors, and suppliers in India benefit from its high purity and long shelf life, as it provides a reliable solution for neuro-muscular symptom management.


Quality Assurance and Storage

Produced under rigorous quality controls, Biperiden boasts a purity not less than 97% and must not lose more than 0.5% on drying. Its shelf life extends up to 3 years when stored at room temperature, provided it is kept in tightly sealed containers. The product adheres to industry standards with a CAS number of 514-65-8 and EINECS number 214-976-2, ensuring traceability and reliability in supply chains.