FLUOCINOLONE ACETONIDE

Product Description

Niksan Pharmaceutical is the largest manufacturer and exporter of the Fluocinolone Acetonide among all over the world. Niksan Pharmaceutical is one of biggest thesupplier, manufacturer, exporter and distributor of the Fluocinolone Acetonide API and finished formulations in Ankleshwar, Gujarat,India. The products of Niksan Pharmaceutical and Niksan group companies arewidely appreciated by the clients and other companies.

NiksanPharmaceuticals are manufacturing and exporting large quantity of FluocinoloneAcetonide in all overthe globe for many years in countries like Hong Kong, United States, Pakistan,India, Philippines, Indonesia, Italy, United Kingdom, Belgium, France, Algeria,Morocco, Netherland, Canada, united states, United Kingdom, Switzerland, Indonesia,Vietnam, Australia, Hungary, Finland, Turkey, Pakistan, Slovenia, Ireland,Zambia, Cyprus, Nigeria, Rwanda, South Africa, Denmark, Malawi, Croatia, Malta,Kazakistan, Slovenia, Bolivia, Japan, Uganda, Uzbekistan, Cameroon,Netherlands, Azerbaijan, Venezuela, Morocco, Cote D Ivoire, St Lucia, SouthKorea, Congo, Philippines,Colombia and Germany and my more countries.

Niksan Pharmaceutical provides Fluocinolone Acetonide to all states of India like Punjab,Rajasthan, Andhra Pradesh, Haryana, Telangana, Bihar, Karnataka, Delhi, TamilNadu, Odisha, Maharashtra, West Bengal, Uttar Pradesh, Gujarat, and MadhyaPradesh etc.  We make all theformulations in the best WHO GMP certified field. We also give gift samples tothe companies for R&D purpose.

Fluocinolone Acetonide comes in the topical steroid class IV.Fluocinolone Acetonide used in the treatment of many skin conditions like rash,irritation, eczema, dermatitis, redness of skin, swelling of skin etc.

SYNONYMS OF FLUOCINOLONEACETONIDE: Acétonidede Fluocinolone, acetónido de fluocinolona, fluocinolon acetonid, FluocinoloneAcetonide, fluocinoloni acetonidum.

IUPAC NAME:(1S,2S,4R,8S,9S,11S,12R,13S,19S)-12,19-difluoro-11-hydroxy-8-(2-hydroxyacetyl)-6,6,9,13-tetramethyl-5,7-dioxapentacycloicosa-14,17-dien-16-one

CAS NO: 67-73-2

FORMULA: C₂₄H₃₀F₂O₆

MOLECULAR MASS: 452.495 g·mol−1

STORAGE CONDITIONS: Store in cool and dry place away from directheat and moisture. Do not keep the container open for long time. Do not placein bathroom or any humid place. Keep away from children and pets.

HOW TO USE: Use the medication 3-4 times per day. Rememberthis medication is for external use only, do not consume it. Carefully wash anddry the part where the cream has to apply.  Apply the medicine gently do not rub it.

HOW FLUOCINOLONE ACETONIDE WORKS:Fluocinolone acetonide is a corticosteroid. It canbe inferred that it acts by inhibiting the fibroblast proliferation,edemacapillary dilation, leukocyte migration, fibrin deposition, capillaryproliferation, collagen deposition, and scar formation on the body.

PHARMACOKINETICS: Fluocinolone Acetonide used for the sustain release. FluocinoloneAcetonide presents the sustain delivery action for straight 12 months. Thesystemic absorption of Fluocinolone Acetonide is very minor. The half-life ofFluocinolone Acetonide is around 1.3-1.7 hours. Thus the systemic absorption isminimal Fluocinolone eliminate from kidney.

SIDE EFFECTS: The reactions like redness of skin, itching,burning, dryness of skin, irritation may see in patients. Tell your doctor ifsome serious side effects like stretch mark, skin rash, decolouration of skin,acne, or hair growth like effects appears. Notify your doctor if reddens swellingdoes not improve. Some rare side effects like rash, itching, swelling of skin,dizziness seen in the patients.

PRECAUTION: Before using the medication tell your doctorif you have any allergic reaction towards the Fluocinolone Acetonide. If youhave problems like blood circulation problem, weak immunity or diabetesproblem, do not use this medication.

Do not use the medication on face or in under arms. FluocinoloneAcetonide can effects on child’s growth if it given for the long time.

CDSCO APPROVAL: Fluocinolone acetonide approved by CDSCO inIndia August-1962

Hydroquinone 20mg + Tretinoin 0.25mg + Fluocinolone Acetonide0.1mg per gm Cream approved by CDSCO in India 23.02.09.

FORMULATION AVAILABLE IN MARKET:

Fluocinolone Acetonide 0.01% w/w cream

Fluocinolone Acetonide 0.01%w/v solution

Fluocinolone Acetonide 0.01%w/w + Miconazole 2% w/w cream

Hydroquinone 20mg + Tretinoin 0.25mg + Fluocinolone Acetonide0.1mg per gm Cream

Note: Product protected by valid patents are notoffered for sale in countries where such patents are still valid and itsliability is at Buyers Risk

REFERENCES:

www.webmd.com

https://pubchem.ncbi.nlm.nih.gov

https://go.drugbank.com

https://cdscoonline.gov.in

https://www.wikipedia.org/

https://www.drugs.com

https://www.zaubacorp.com

https://www.practo.com/consult