MELATONIN .

Name: MELATONIN .
Brand: NIKSAN PHARMACEUTICAL
Price: 11000.00 INR
Availability: InStock

11000.00 INR/Kilograms

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Product Details:

Storage Room Temperature
Structural Formula C13H16N2O2
Taste Other
Solubility Soluble in Acetone,Methanol and Slightly soluble in Water
Molecular Weight 232.278 g/mol Grams (g)
Shelf Life 3 Years
Smell Other
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MELATONIN . Price And Quantity

Minimum Order Quantity 1 Kilograms
Price 11000.00 INR/Kilograms

MELATONIN . Product Specifications

Grade Medicine Grade
Chemical Name N-[2-(5-methoxy-1H-indol-3-yl)ethyl]acetamide
HS Code 29420090
EINECS No 200-797-7
Molecular Formula C13H16N2O2
Purity(%) 99 %
Heavy Metal (%) NA
Melting Point 116.5 to 118C
Ph Level pH 1
Particle Size nanometers to tens of micrometers
Boiling point 512.8 C
Loss on Drying NA
Shelf Life 3 Years
Smell Other
Molecular Weight 232.278 g/mol Grams (g)
Appearance White to Off-White Solid
Type Other
Solubility Soluble in Acetone,Methanol and Slightly soluble in Water
Physical Form Powder
Structural Formula C13H16N2O2
Usage It helps with the timing of your circadian rhythms and with sleep insomnia and improving sleep in different conditions
Taste Other
CAS No 73-31-4
Storage Room Temperature
Medicine Name MELATONIN

MELATONIN . Trade Information

FOB Port INDIA
Supply Ability 100 Kilograms Per Month
Delivery Time 1 Days
Sample Available No
Packaging Details HDPE DRUM WITH TWO INNER LDPE LINNER
Main Domestic Market All India
Certifications GMP, FDCA

Product Description

is leading manufacturer and distributer of the Melatonin among the other countries. Niksan Pharmaceutical is oneof the major the supplier, distributer, exporter and manufacturer of the Melatonin API andfinished formulations in Ankleshwar, Gujarat, India. The products of NiksanPharmaceutical and Niksan group companies are widely appreciated by the clientsand other companies.

Niksan Pharmaceutical is the supplier,manufacturer, exporter and trader of Melatonin in the domestic level as well as the internationalmarket.

Niksan Pharmaceutical provides Melatonin API in allover Indian states like Jammu & Kashmir, Himachal Pradesh, Uttarakhand,Punjab, Kerala, Chandigarh, Chhattisgarh, Andhra Pradesh, Rajasthan, Meghalaya, Mizoram,Nagaland, Orissa,, Dadra and NagarHaveli, Goa, Gujarat,Jharkhand, West Bengal, Karnataka, Kerala, Madhya Pradesh etc.

Niksan Pharmaceutical also provides Melatonin API and finished formulations in all othercountries of the world like Germany, Switzerland, Poland, Latvia, Egypt,Lithuania, Estonia, Ukraine, Moldova, Russia, United States, Austria, Belarus,Serbia, India, Spain, Slovenia, Nigeria, Croatia, South Africa, Kazakhstan,Italy, Romania, Bulgaria, Portugal, South Korea, Greece, Philippines, Belgium,Saudi Arabia, Turkey, Japan etc.

Melatonin are two types: natural and synthetic (manmade). Natural melatonin is made from the pineal gland ofanimals. This form could be contaminated with a virus, so its not recommended.The synthetic form of melatonin doesnt carry this risk.

SYNONYMS: Melatonin, N-Acetyl-5-methoxytryptamine

IUPAC NAME: N-[2-(5-methoxy-1H-indol-3-yl)ethyl]

CAS NO: 73-31-4

FORMULA: C₁₃H₁₆N₂O₂

MOLECULAR MASS:232.278 g/mol

STORAGE OF MELATONIN:It has been found as melatonin has an acceptable stability inall storage conditions tested: Darkness at -32C, darkness at 4C, darkness at25C, darkness at 50C, light at -32C, light at 4C, light at 25C and lightat 50C until day 13, except the samples kept at room temperature in light.

APPLICATIONS OF MELATONIN:People most commonly use melatonin for insomnia and improving sleep indifferent conditions, such as jet lag. It isalso used for depression, chronic pain, dementia, and many other conditions,but there is no good scientific evidence to support most of these uses.

The usual starting dose is one 2mg slow release tablet taken 30minutes to 1 hour before bedtime.

HOW MELATONIN WORKS: Melatoninis a hormone thatyour brain produces in response to darkness. Ithelps with the timing of your circadian rhythms (24-hour internal clock) andwith sleep. Being exposed to light at night can block melatonin production.

CONTRAINDICATIONS OF MELATONIN: Bleedingdisorders: Melatonin might make bleeding worsein people with bleeding disorders. Depression: Melatonin can make symptoms ofdepression worse. High blood pressure: Melatonin can raise blood pressure inpeople who are taking certain medications to control blood pressure. Avoidusing it.

PHARMACOKINETICS OF MELATONIN: melatonin regulates the sleep-wake cycle bychemically causing drowsiness and lowering the body temperature. Melatonin is also implicated in the regulation of mood,learning and memory, immune activity, dreaming, fertility and reproduction.Melatonin is also an effective antioxidant.

SIDE EFFECTS OF MELATONIN: In some cases, Feeling sleepy or tired in the daytime. Donot drive, cycle or use tools or machinery if youre feeling this way,Headache.Make sure you rest and drink plenty of fluids, Stomach ache, Feeling sick(nausea) , Feeling dizzy, Feeling irritable or restless,Dry mouth, Dry or itchyskin.

PRECAUTIONS: melatonin can causedrowsiness, dontdrive or use machinery within five hours of taking it. Melatonin supplements can interact with some types of medicine,including: Medicine that slows blood clotting. Medicine that prevents seizures.

CDSCO APPROVAL:

Melatonin tablets are approved by CDSCOin India in 12/03/1998

FORMULATION AVAILABLEIN MARKET:

Melatonin 3 MGtablets

Melatonin 5 MGtablets

Melatonin 10MG tablets

Melatonin 3 MGCapsules

Note: Product protected by validpatents are not offered for sale in countries where such patents are stillvalid and its liability is at Buyers Risk

REFERENCES:

www.webmd.com

https://pubchem.ncbi.nlm.nih.gov

https://go.drugbank.com

https://cdscoonline.gov.in

https://www.wikipedia.org/

https://www.drugs.com

https://www.zaubacorp.com

https://www.practo.com/consult

Regulation of Sleep and Circadian Rhythms

Melatonin plays a pivotal role in synchronizing the bodys internal clock with the day-night cycle. This hormone aids individuals experiencing insomnia, jet lag, or shift work-related sleep disturbances by promoting the onset of sleep and supporting restorative rest. Its timely administration can improve sleep quality and overall well-being.

Versatile Pharmaceutical-Grade Application

Processed as a fine powder with high purity, melatonin is suitable for use in various formulations, including tablets, capsules, and suspensions. Its consistent particle sizeranging from nanometer to micrometersensures uniform mixing and dosing accuracy. This versatility meets the stringent standards required for medicine-grade substances.

Quality, Purity, and Handling

Manufactured and distributed by trusted suppliers in India, this melatonin complies with relevant HS and EINECS codes for international trade. It offers a stable shelf life of up to three years at room temperature, with optimal material handling and minimal degradation riskmaking it a reliable choice for manufacturers and traders alike.

FAQs of MELATONIN:

Q: How does melatonin help regulate sleep cycles and insomnia?

A: Melatonin works by influencing the circadian rhythm, the bodys natural sleep-wake cycle. Supplementing with melatonin can improve the timing and quality of sleep, particularly in those with insomnia or disrupted sleep schedules, such as shift workers or travelers experiencing jet lag.

Q: What is the recommended storage condition for melatonin powder?

A: Melatonin powder should be stored at room temperature in a dry and well-sealed container. Proper storage helps preserve its 99% purity and extends its shelf life up to three years.

Q: When is melatonin typically used in medical or industrial processes?

A: Melatonin is used when there is a need to address sleep disorders, insomnia, or disturbances in circadian rhythms. In industrial and pharmaceutical applications, it is incorporated into various formulations including tablets, capsules, and powders for export and supply.

Q: Where is your melatonin sourced and distributed from?

A: Our melatonin is manufactured, supplied, exported, and distributed from India, adhering to international quality and purity standards as indicated by CAS No: 73-31-4 and EINECS No: 200-797-7.

Q: What is the process to ensure melatonins quality and purity?

A: The manufacturing process for melatonin follows stringent industry standards, ensuring its purity reaches 99%. The final product is tested for consistency in particle size, appearance, and solubility, meeting medicine-grade specifications.

Q: How is melatonin used in pharmaceutical applications?

A: Due to its high purity and suitable physical form, melatonin is typically formulated into pharmaceutical preparations such as capsules, tablets, or oral powders. Its controlled particle size ensures precise dosing and effective delivery.

Q: What are the primary benefits of using high-purity melatonin?

A: High-purity melatonin offers reliable efficacy in supporting sleep health, helps synchronize circadian rhythms, and enhances the quality of rest. It is also advantageous for manufacturers, ensuring consistent results and safety for end users.

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Contact Details

Plot No. 4706/03, Gidc Estate, SF-12, Shrinathji Arcade, Near Meghmani Chowkadi,Ankleshwar - 393002, Gujarat, India
Phone :91--9537871777
Email : info@niksanpharmaceutical.com

Mr SANJAY PATEL (SALES DEPARTMENT)
Mobile :+919537871777
info@niksanpharmaceutical.com
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