SILODOSIN

Product Description

NiksanPharmaceutical is one of the leading manufacturer, supplier and exporter of the Silodosin. The best product manufactured by NiksanPharmaceutical is Silodosin. Wemanufacture, supply and export best quality product of Silodosin API along withSilodosin formulations.

NiksanPharmaceutical providesbest quality product of Silodosin in all states of India like Kerala, Punjab, Rajasthan, Telangana, Bihar, Karnataka, Jammu andKashmir, Maharashtra, West Bengal, Uttar Pradesh, Gujarat, Delhi, Tamil Nadu,Odisha, Madhya Pradesh, Andhra Pradesh, Haryana and many other states.

NiksanPharmaceutical is alsomanufacture and exports large quantity of Silodosin products in whole globe since many years incountries like Nepal, Taiwan, United Arab Emirates, Bangladesh, Iraq, Ireland,South Korea, Canada, Egypt, Indonesia, United States, Thailand, Philippines,Turkey, Nigeria, Australia, Germany, Malaysia, Vietnam, Spain, United Kingdom,Poland and many more countries.

Silodosin belongs to the alpha-blocker class of medicine.Silodosin used in the treatment of enlarged prostate.

ENLARGEDPROSTATE: Enlargedprostate cause difficulty in urination, pain full urination and 

also causetrouble in urine urgency.

Silodosin also called alpha-adrenoceptor antagonistwhich isused in the treatment of BPH.

SYNONYMS: Silodosin, Silodosina

IUPAC NAME:1-(3-hydroxypropyl)-5-[(2R)-({2-[2-[2-(2,2,2-

Trifluoroethoxy) phenoxy] ethyll} amino)propyl]indoline-

7-carboxamide

CAS NO: 160970-54-7

FORMULA: C₂₅H₃₂F₃N₃O₄

MOLECULARMASS:495.534 g/mol

STORAGE CONDITIONS: Store in cool and dry place, away from lightand heat. Do not put it infringe or in bathroom. Keep away from children andpet.

HOW TOUSE: Take Silodosin tablet/capsule orally with food onetime per day. Take doctors’ advice before taking medicine. Silodosin comes incapsule so do not chew it or do not open it.

HOW SILODOSINWORKS: Silodosinblocks the alpha A1 receptors which located in urethra and bladder. By blockingthese receptors Silodosin relaxes the smooth muscles and by this process theflow of urination improves.

PHARMACOKINETICSOFSILODOSIN: Normally Silodosin absorbed by the gut. The AUC and peak plasma levelmay have effected by the food. The bio availability of Silodosin is 32%. Themetabolism of Silodosin is done in liver. The half-life of Silodosin is approx.irately 13.38.07 hrs. The rout of elimination of Silodosin is renal 33.5% andby faecal 54.9%.

SIDE EFFECTSOFSILODOSIN: The side effects of Silodosin are ejaculation problem, fainting,headache, dizziness, light headed ness. If you have side effect like faintingor weakness contact your doctor and take advice. There are some rare sideeffects like rash, allergy, and redness of skin, itching or trouble inbreathing.

PRECAUTIONSOF SILODOSIN: Tellyour pharmacist if you have any allergic reaction to the Silodosin. Also tellyour doctor if you have any disease related to lung, heart, liver or kidney. Donot drive or use any machinery because Silodosin makes you dizzy. Take lessamount of alcohol and also if you are using cannabis talk to your doctor aboutusing it

CDSCOAPPROVAL: SilodosinCapsules 2mg/4mg/8mg approved by CDSCO in India in23.06.2011

Silodosin Tablets 4mg approved by CDSCO inIndianin 10.04.2012

FORMULATIONSAVAILABLE INMARKET:

Silodosin 2 mg capsules

Silodosin 4mg capsules

Silodosin 8mg capsules

Silodosin 4 mg tablets

Silodosin 8 mg tablets

Silodosin 4mg + Dutasteride 0.5mg tablets

Silodosin 8mg + Dutasteride 0.5mg tablets

Note: Product protected by valid patents arenot offered for sale incountries where such patents are still valid and itsliability is at Buyers Risk.

REFERENCES:

www.webmd.com

https://pubchem.ncbi.nlm.nih.gov

https://go.drugbank.com

https://cdscoonline.gov.in

https://www.wikipedia.org/

https://www.drugs.com

https://www.zaubacorp.com

https://www.practo.com/consult