CILNIDIPINE

Product Description

 Niksan Pharmaceutical is a leading manufacturer of Cilnidipine in Ankleshwar, Gujarat, India, and we supply this product to all Indian states and many countries like Sri Lanka, United Arab Emirates, Australia, United States, United Kingdom, Japan, and Korea. Calcium channel blockers include cilnidipine. This is primarily an antihypertensive agent. The API of Cinnidipine is compatible with other API, such as Telmisartan, Ramipril, Olmesartan Medoxomil, and Metoprolol Succinate. Furthermore, cilnidipine can also interact with the N-type calcium channel. cilnidipine reduces capillary bed pressure by dilating arterioles and venules. 

Niksan Pharmaceutical provides Cilnidipine to all states of India like Punjab, Rajasthan, Andhra Pradesh, Haryana, Telangana, Bihar, Karnataka, Delhi,Tamil Nadu, Odisha, Maharashtra, West Bengal, Uttar Pradesh, Gujarat, and Madhya Pradesh etc. We also give gift samples to the companies for R&D purpose. Cilnidipine comes under the calcium channel blocker class of medicine. Most of it is used as anti-hypertensive agent. Cilnidipine have compatibility with other API like Telmisartan, Olmesartan Medoxomil, Ramipril and Metoprolol Succinate. Cilnidipine can act on the N-type calcium channel in addition to acting on the L-type calcium channel. Cilnidipine dilates both arterioles and venules, reducing the pressure in the capillary bed. 

IUPAC NAME: 3-(2-methoxyethyl)5-(2E)-3-phenylpr op-2-en-1-yl2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate  

CASNO: 132203-70-4 

FORMULA: C₂₇H₂₈N₂O₇ 

MOLECULAR MASS: 492.52 g/mol 

STORAGE: Store the medicine in cool and dry place. Store it away from the direct sun light. Do not change packet of the Cilnidipine tablet. Keep away from reach of children and pets. 

APPLICATION:  Cilnidipineis primarily used for the treatment of high blood pressure also referred to ashypertension. The Cilnidipine have the calcium channel blocker activity it is also used in the treatment of headache, vision related problems, irregular heartbeat, chest pain, and fatigue. 

HOW TO USE: Simply take the medicine as per your doctor says. The tablet should be taken orally with water. The tablet must be swallowed whole without breaking or chewing. 

HOW CILNIDIPINE WORKS: Cilnidipine blocks the calcium channels in blood vessels. By this the blood supplies towards the heart increase and by that the hypertension decreases. 

CONTRAINDICATIONS: Do not take Cilnidipine medicine in pregnancy and lactation period. Do not give medicine to the patient under 18 years. If you have any confusion related to the medicine consult to your doctor. 

PHARMACOKINETICS: Cilnidipine is one type of lipophilic drug. So mainly it is metabolites in the liver or kidneys. Cilnidipine is rapidly absorbed in the blood plasma in only 2hrs .Cilnidipine normally excreted by urination. 

SIDE EFFECTS: There are some common side effects of the Cilnidipine are Dizziness, hypotension,swelling of (face, eyes, tongue, and feet), fast heartbeats, muscle pain,stomach pain, skin rash. 

PRECAUTIONS: Dont take medicine if you are allergic to Cilnidipine. If you have any heart or liver problem kindly find some alternative of Cilnidipine. The effect of Cilnidipine is not known yet so do not take it if you are breastfeeding the baby. Do not share the medicine with other people. 

CDSCO APPROVAL:  Cilnidipine tablet 5mg approved by CDSCO in India in 21.06.2007.

Cilnidipine tablet 10 mg is approved by CDSCO in 21.06.2007.

FORMULATIONSIN MARKET:

Cilnidipine 5 mg Tablets

Cilnidipine 10 mg Tablets

Cilnidipine 20 mg Tablets

Cilnidipine 5 mg + Telmisartan 20 mg Tablets

Cilnidipine10 mg + Telmisartan 40 mg Tablets

Cilnidipine 10 mg + Metoprolol Succinate 25mg Tablets

Cilnidipine 10 mg + Metoprolol Succinate 50mg Tablets

Cilnidipine 10 mg + Olmesartan Medoxomil 20mg Tablets

Cilnidipine 10 mg + Olmesartan Medoxomil 40mg Tablets

Cilnidipine 10 mg + Ramipril IP 10 mg Capsules

Cilnidipine 10 mg + Ramipril IP 2.5 mgCapsules

Cilnidipine 5 mg + Hydrochlorothiazide 12.5mg + Telmisartan 40 mg capsules

Note: Product protected by valid patents are not offered for sale in countries where such patents are still valid and its liability is at Buyers Risk

REFERENCES: 

www.webmd.com

https://pubchem.ncbi.nlm.nih.gov

https://go.drugbank.com

https://cdscoonline.gov.in

https://www.wikipedia.org/

https://www.drugs.com

https://www.zaubacorp.com

https://www.practo.com/consult