KETOPROFEN

Product Description

is one of the biggest manufacturer, supplier, exporter and trader ofthe KETOPROFENfinished formulations moreover Ketoprofen API. Niksan Pharmaceutical is the huge manufacturer, exporter andsupplier of Ketoprofen API and formulation situated in Ankleshwar, Gujarat, India.

NiksanPharmaceutical is the suppliers, manufacturer, exporters and trader of
Ketoprofen inthedomestic level as well as the international market.

 

Niksan is anIndian based pharmaceutical company so it also supplies and manufactures the Ketoprofen to allIndian states like Gujarat, Maharashtra, Punjab, Delhi, Tamilnadu, Goa, UttarPradesh, Karnataka, Jammu & Kashmir, West Bengal, Assam, Rajasthan,Hyderabad, Karnataka, Kerala, Madhya Pradesh, Manipur,Meghalaya, Mizoram, Nagaland, Orissa, Punjab and Haryana.  

 

NiksanPharmaceutical and Niksan group companies are exporters, suppliers andmanufacturers of the API and also Ketoprofen formulations in many countries for many years. Niksanpharmaceutical currently exports Ketoprofen API and Formulation to countries like New Zealand, Jordan,Belgium, United Kingdom, Australia, Italy, Ireland, Hong Kong, Morocco,,Portugal, France, South Africa, Philippines, Malaysia, Singapore, Israel,Greece, Saudi Arabia, Egypt, Taiwan, Netherlands, South Korea, Switzerland,Algeria, Pakistan, Canada, Vietnam, United States, Germany, Brazil and manyother countries.

 

KETOPROFENis a nonsteroidalanti-inflammatory drug (NSAID) of the propionic acid class. It is used for itsanalgesic and anti-inflammatory effects in treating pain, inflammation, andfever.

 

SYNONYSMS:Ketonal, Orudis, Oruvail

 

IUPAC NAME: (2RS)-2-(3-benzoylphenyl)propanoicacid

 

CAS NO:22071-15-4

 

FORMULA:C16H14O3

 

MOLECULAR MASS:  254.28 g/mol

 

STORAGE CONDITIONS:Store Ketoprofen at 20C to 25C (68F to77F). Protect from light, excessive heat, and moisture. Store in a tightlyclosed container in a dry place.

 

HOW TO USE:Ketoprofen is usuallytaken 2 to 3 times daily, depending on the formulation and strength. It shouldbe taken with food or milk to minimize gastrointestinal discomfort. Dosage mustbe prescribed by a physician based on the condition being treated.

 

HOW KETOPROFENWORKS:Ketoprofenworks by inhibiting the synthesis of prostaglandins, substances in the bodythat cause inflammation, pain, and fever. It blocks the enzyme cyclooxygenase(COX), which is essential in prostaglandin production.

 

PHARMACOKINETICSOF KETOPROFEN:Ketoprofen is rapidly absorbed after oral administration. It bindsextensively to plasma proteins (>99%) and is metabolized in the liver viaconjugation with glucuronic acid. It is eliminated primarily via the kidneys.

 

SIDE EFFECTSOF KETOPROFEN:Stomachpain, Nausea, Constipation or diarrhea, Headache, Drowsiness or dizziness, Rashor skin irritation, Increased risk of cardiovascular or gastrointestinal eventswith long-term use

 

PRECAUTIONS: Avoid usingKetoprofen in patients with known hypersensitivity to NSAIDs. Use with cautionin individuals with peptic ulcer, liver or kidney disorders, or cardiovasculardiseases. Always take as prescribed by a doctor. Not recommended duringpregnancy and breastfeeding unless absolutely necessary.

 

CDSCOAPPROVAL: 

Dexketoprofen (as Trometamol) tablets12.5mg/25mg 28.03.08

Ketoprofen 50 mg 1981-April Dexketoprofen Trometamol Gel 12.5mg/gm 13.10.09 Dexketoprofen Trometamol Injection 50mg/2ml 22.10.09 Ketoprofen plaster 30 mg (7cm X 10 cm) 11.12.09 Ketoprofen controlled release capsules 1989-Jul Ketoprofen Plaster 30mg (7cm X 10cm) 18.04.12 Dexketoprofen Trometamol ER Tablet 50mg (Additional Strength) 21.02.11 Ketoprofen transdermal patches 17-05-1999 Dexketoprofen 12.5 mg/25 mg + Paracetamol 500 mg film coated tablets 18.05.09 Dexketoprofen Trometamol 25mg + Thiocolchicoside 4mg tablets 20.05.10 Thiocolchicoside 4mg/8mg + Ketoprofen 50mg/100mg tablets 11.06.08 Dexketoprofen1.25% w/w +Linseed Oil 3.0%w/w +Menthol 5%w/w +Methyl Salicylate 10%w/w (12.5mg) 06.07.10 Dexketoprofen 50mg + Dicyclomine 20mg per 2ml Injection 28.04.11

 

FORMULATIONSAVAILABLE IN MARKET:

KETOPROFEN 50 MG tablets

KETOPROFEN 100 MG tablets

KETOPROFEN GEL

KETOPROFEN INJECTON

 

Note: Productprotected by valid patents are not offered for sale in countries where suchpatents are still valid and its liability is at Buyers Risk

 

Key Features and Composition

Ketoprofen is a high-purity (99.9%), white or off-white powdered compound with a molecular formula C16H14O3. Its melting point is 95C and its boiling point reaches 431.3C. With a particle size below 20 m, it offers consistency in pharmaceutical formulations. The product maintains stability with a loss on drying of less than 1% and is stored safely at room temperature to retain its shelf life for three months.


Primary Uses and Benefits

Ketoprofen is widely recognized for its efficacy in managing minor aches and pains, including headaches, toothaches, menstrual discomfort, muscle and back pain, as well as fever reduction. The product is popular in various formulations due to its rapid action and tolerability. Its use extends across multiple healthcare needs, making it a versatile option for pain relief.


Distribution and Supply Chain

This Ketoprofen grade is distributed, exported, imported, and supplied by numerous reliable Indian companies. It is manufactured under stringent quality controls to ensure high purity and efficacy. The products compliance with international standards makes it suitable for the global pharmaceutical market, catering to diverse clientele requirements.