NiksanPharmaceutical is among worlds top most manufacturer, supplier,exporter and trader of the Allopurinol finished formulations moreover AllopurinolAPI. Niksan Pharmaceutical is the huge manufacturer, exporter and supplier of AllopurinolAPI and formulation situated in Ankleshwar, Gujarat, India.
Niksan Pharmaceutical provides API andfinished formulations of Allopurinol in all over Indian states LikeKerala, Gujarat, Haryana, Rajasthan, Madhya Pradesh, Uttar Pradesh, Rajasthan,Karnataka, Meghalaya, Tamilnadu, Goa, Sikkim, Assam, Punjab, Delhi, Bihar,Jammu Kashmir Etc.
NiksanPharmaceutical is also large exporter of the API and finishedpharmaceutical products of Allopurinol in many countries for years. Thecountries where we exporting are Indonesia, Philippines, New Zealand, UnitedStates,Germany, Puerto Rico,Canada, Malaysia, Singapore, Australia, Hong KongIreland, United Kingdom, Vietnam, Kenya, Austria, Jordan, Netherlands, Belgium,Thailand, Nigeria, United Arab Emirates, Sweden, Switzerland, Argentina,France, South Africa, Iraq, Denmark, Saudi Arabia, Taiwan, Pakistan, Norway,Czechia, Israel, Romania, Egypt, South Korea, Hungary, Iran, Poland, Turkey,Spain, Mexico, Brazil, Italy, Japan and many more countries.
Allopurinol belongsto medicine class called xanthine oxidase inhibitors. Allopurinol used in thetreatment of kidney stones. Allopurinol works by decreasing the production ofuric acid in body and prevents the risk of kidney stone and gout.
SYNONYMS: 4-HPP, Allopurinol,Allopurinolum, Alopurinol
IUPAC NAME:1H-pyrazolo [3,4-d] pyrimidin-4-ol
CAS NO: 315-30-0
FORMULA: C5H4N4O
MOLECULAR MASS: 136.112 g/mol
STORAGE CONDITIONS: Store in room temperature indry place.
Do not put medicine in bathroom or kitchen.
Keep away from children and pets.
HOW TOUSE: Take Allopurinol tablet once daily orally as directed by doctor.Takethis medication with food to prevent the stomach upset.Take medication withfull glass of water to get best effect.
HOWALLOPURINOL WORKS: Allopurinol is xanthine oxidase inhibitor,Allopurinol acts by inhibiting the conversion of xanthine oxidase to xanthineto uric acid.Allopurinol inhibits the uric acid synthesis and prevents the riskof kidney stone and gout problem.
PHARMACOKINETICS:90% of Allopurinol absorbed in GI track after the oral administration.Ittakes normally 1.5-4.5 hours to reach the peak plasma concentration.
Almostvery small amount of Allopurinol binds with the plasma protein.The half-life ofAllopurinol is between 1-2 hours.Allopurinol has rapid renal clearance andalmost 80% of drug excreted by the urination.
SIDEEFFECTS: Allopurinol has side effects like nausea, stomach upset, stomach pain,vomiting, dizziness, drowsiness. Tell your doctor if you see side effects likenumbness, easy bleeding, kidney problem, dark urine, stomach/intestinal pain,eye pain, vision change, Other rare side effects like fever, swollen, rash,itching, dizziness, trouble in breathing.
PRECAUTIONS:IF you have medical history like liver disease, kidney problem, highblood pressure, fasting, diabetes problemtell your doctor about it.Beforetaking medication tell your doctor if you have allergies to Allopurinolmedication.
This drugmakes you drowsy so do not take any alcoholic beverage or cannabis.
Do notdrive or operate a vehicle after taking the medication.
CDSCOAPPROVAL: Allopurinol S.R. caps approved by CDSCO in India in 22-11-2002,
Allopurinoltablet approved by CDSCO in India in March-1969
FORMULATIONS AVAILABLE IN MARKET:
Allopurinol 100mg tablet
Allopurinol 250mg tablet
Allopurinol 300mg tablet
Note: Product protected by validpatents are not offered for sale in countries where such patents are stillvalid and its liability is at Buyers Risk
REFERENCES:
www.webmd.com
https://pubchem.ncbi.nlm.nih.gov
https://go.drugbank.com
https://cdscoonline.gov.in
https://www.wikipedia.org/
https://www.drugs.com
https://www.zaubacorp.com
https://www.practo.com/consult
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