Ambroxol Ambroxol Ambroxol Ambroxol Ambroxol Ambroxol
Ambroxol
Ambroxol Ambroxol Ambroxol Ambroxol Ambroxol

Ambroxol

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Niksan Pharmaceutical is among worlds top most manufacturer, supplier, exporter and trader of the Ambroxol finished formulations moreover Ambroxol API. Niksan Pharmaceutical is the huge manufacturer, exporter and supplier of Ambroxol API and formulation situated in Ankleshwar, Gujarat, India.

Niksan Pharmaceutical provides API and finished formulations of Ambroxol in all over Indian states Like Kerala, Gujarat, Haryana, Rajasthan, Rajasthan, Karnataka,Meghalaya, Tamilnadu, Goa, Sikkim, Assam, Punjab, Delhi, Bihar, Jammu, Madhya Pradesh, Uttar Pradesh, Kashmir Etc.

Niksan Pharmaceutical is also large exporter of the API and finished pharmaceutical products of Ambroxol in many countries for years. The countries where we exporting are Mexico, Nicaragua, Indonesia, Guatemala, Honduras, Philippines,Dominican Republic, Panama, El Salvador, Hungary, Ecuador, Peru, Paraguay,Chile, Bolivia, Romania, Moldova, Venezuela, Costa Rica, Brazil, Lithuania,Germany, Vietnam, United Arab Emirates, Austria, Colombia, Bangladesh, Spain,Taiwan, Hong Kong, Argentina, Czechia, Singapore, Malaysia, Thailand, Portugal,Egypt, South Korea, Saudi Arabia, Switzerland, France, United States, Italy,Poland, Canada, United Kingdom, Japan and many more countries.

Ambroxol is a mucolytic agent. Ambroxol removes the mucus from the airway bythinnIg down the mucus and making it less sticky. Ambroxol used in the treatment of the respiratory disease associated with excessive mucous  

SYNONYMS: Ambroxolum ,Bisolvon metabolite vIII, Bromhexine metabolite vIII, Ambroxol 

IUPAC NAME:( 1r, 4r)-4-{[(2-amino-3, 5-dibromophenyl)methyl] amino} cyclohexan-1-ol

CAS NO:18683-91-5 

FORMULA: C13H18Br2N2O 

MOLECULAR MASS: 378.10 g/mol 

STORAGE CONDITIONS: Store in cool and dry place. Donot place the container in humid place like bathroom or kitchen.  Dont put container open.  Keep away from children and pets 

HOW TO USE: Take 1-4 tablets in 2-3 divided doses. Give one teaspoon syrup to the 5 year old children 2-3 times a day. Take the medication regularly for the better result. 

HOW AMBROXOL WORKS: Ambroxolinhibits the guanylate cyclase. By this activity  suppress the excessive secretion of mucous. Ambroxolalso decrease the phlegm viscosity and makes it less stick. 

PHARMACOKINETICS: Almost all Ambroxol medication absorbed in body after the oral administration. This drug binds with almost 90% of blood plasma proteins. The half-life of the medicine is between 7-12 hours. The drug is metabolized in liver. About 90% of Ambroxol excreted by the urination 

SIDE EFFECTS: The most common side effect of Ambroxolis runny nose. The other side effects like GI irritation, abdominal problems. Tel lyour doctor if you see some side effects like skin rash, allergic reaction,itching, swelling of skin and breathing problem. 

PRECAUTIONS: Tell your doctor if you have allergic reactions to the Ambroxol. Take your doctors advice before giving the medication to children. If you see any side effects contact your doctor at early stage 

CDSCO APPROVAL: Azithromycin 500mg + AmbroxolS.R (75mg) Tablet appoved by CDSCO in India in 05.07.2007

Cetirizine 10 mg + Ambroxol 75 mg SR Tablet approved by CDSCO in  India in 13.04.2009

Gatifloxacin + Ambroxol tablets approved by CDSCO in India in 24.12.2004

Levofloxacin (250mg/500mg) + Ambroxol SR 75mg tablet approved by CDSCO in India in 08.02.2007

Desloratadine (2.5mg) + Ambroxol (30mg) + Guiphenasine (50mg) +Menthol 1mg/5ml Syrup approved by CDSCO in India in 02.03.2005

 Ambroxol + loratadine +Guaifenesin Syrup (30mg + 5mg + 50mg per 5ml) approved by CDSCO in India in 18.08.2008

Ambroxol 30 mg+ Terbutaline 2.5 mg + Guiphenasine 100mg + Menthol2.5 mg per 5 ml syrup approved by CDSCO in India in 27.10.2009

 Ambroxol HCl + salbutamol +guaiphenesin + menthol approved by CDSCO in India in 16.06.1999

 Doxofylline 400 mg +Ambroxol 30 mg Tablets approved by CDSCO in India in 23.12.2009

Gemifloxacin + Ambroxol (320mg + 75mg SR) FC Tablets approved by CDSCO in India in 24.12.2008

Ambroxol tablet/liquid/drops        approved by CDSCO in India in 01.12.1995

 Ambroxol + Guaiphenesin approved by CDSCO in India in 18.08.2000

Ambroxol + Guaiphenesin + Menthol + Pseudoephedrine approved by CDSCO in India in 29.10.1999

Levocetirizine 5mg + Ambroxol Hydrochloride SR (75mg) tablet approved by CDSCO in India in 24.05.2006

 Ambroxyl HCl SR+Doxycycline HCl approved by CDSCO in India in 23.08.2001

FDC of Ambroxol + guaiphenesin approved by CDSCO in India in 10.09.2001

FDC of Levocetirizine (5mg) + Ambroxol (75mg S.R) Capsule approved by CDSCO in India in 29.07.2005

 Olopatadine 5mg + Ambroxol 30mg tablets approved by CDSCO in India in 05.03.2010

 Ambroxol CR tabs approved by CDSCO in India in 2002

Ambroxol + Pseudoephedrine + Chlorpheniramine maleate  tabs/suspension/syrup approved by CDSCO in India in 26.02.1998

Levocetrizine 2.5/5mg + Ambroxol 30mg/5ml of syrup approved by CDSCO in India in 20.07.2006 

Cetirizine 5/10mg + Ambroxol 30mg per 5ml syrup approved by CDSCO in India in 23.02.2009

 Ambroxol 30mg +Levosalbutamol 1mg + Guiphenesin 50mg /5ml syrup approved by CDSCO in India in 19.03.2009

Ambroxol HCl. 15mg + Guiphenesin 50mg + Terbutaline sulphate1.25mg + Menthol 2.5mg per 5 ml of syrup approved by CDSCO in India in 26.03.2008

 Ambroxol HCl 75mg (S.R) +Desloratadine 5mg Capsule approved  by CDSCO in India in 11.11.2005

Levocetirizine 2 HCl 5mg+ Ambroxol HCl SR 75mg + Pseudoephedrine HCl120mg SR Capsules approved by CDSCO in India in 09.08.2006

 Ambroxol HCl 30mg +Guaiphenesin 100mg + Terbutaline sulphate 2.5mg per 10ml Syrup approved by CDSCO in India in 26.03.2008

 

FORMULATIONS AVAILABLE IN MARKET:

Ambroxol HCl 30mg + Guaiphenesin 100mg + Terbutaline sulphate 2.5mg per 10ml Syrup

Ambroxol HCl 75mg (S.R) + Desloratadine 5mg Capsules

Levocetirizine 2 HCl 5mg+ Ambroxol HCl SR 75mg + Pseudoephedrine HCl 120mg SR Capsules

Ambroxol HCl. 15mg + Guiphenesin 50mg + Terbutaline sulphate 1.25mg + Menthol 2.5mg per 5 ml of syrup

Ambroxol 30mg + Levosalbutamol 1mg + Guiphenesin 50mg /5ml syrup

Cetirizine 5/10mg + Ambroxol 30mg per 5ml syrup

Levocetrizine 2.5/5mg + Ambroxol 30mg/5ml of syrup

Ambroxol + Pseudoephedrine + Chlorpheniramine maleate tabs

Ambroxol + Pseudoephedrine + Chlorpheniramine maleate syrup

Ambroxol + Pseudoephedrine + Chlorpheniramine maleate suspension

Ambroxol CR tablets

Olopatadine 5mg + Ambroxol 30mg tablets

FDC of Levocetirizine (5mg) + Ambroxol (75mg S.R) Capsule

Ambroxyl HCl SR+ Doxycycline HCl tablets

Levocetirizine 5mg + Ambroxol Hydrochloride SR (75mg) tablets

Ambroxol + Guaiphenesin tablets

Ambroxol tablets

Ambroxol drops

Ambroxol liquid

Gemifloxacin + Ambroxol (320mg + 75mg SR) FC Tablets

Doxofylline 400 mg + Ambroxol 30 mg Tablets

Mbroxol 30 mg+ Terbutaline 2.5 mg + Guiphenasine 100mg + Menthol2.5 mg per 5 ml syrup

Desloratadine (2.5mg) + Ambroxol (30mg) + Guiphenasine (50mg) +Menthol 1mg/5ml Syrup

Levofloxacin (250mg/500mg) + Ambroxol SR 75mg tablets

Azithromycin 500mg + Ambroxol S.R (75mg) tablets

 

Note: Product protected by valid patents are not offered for sale in countries where such patents are still valid and its liability is at Buyers Risk

 

REFERENCES: 

www.webmd.com

https://pubchem.ncbi.nlm.nih.gov

https://go.drugbank.com 

https://cdscoonline.gov.in 

https://www.wikipedia.org/

https://www.drugs.com

https://www.zaubacorp.com

https://www.practo.com/consult

 

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