is the largest manufacturer and exporter of the Clarithromycinamong all over the world. NiksanPharmaceutical is one of biggest the supplier, manufacturer, exporter anddistributor of the ClarithromycinAPI and finishedformulations in Ankleshwar, Gujarat, India. The products ofNiksan pharmaceutical and Niksan group companies are widely appreciated by theclients and other companies.
Niksan Pharmaceutical provides API and finishedformulations of Clarithromycin inall over Indian states Like Kerala, Gujarat, Haryana, Rajasthan, Rajasthan,Karnataka, Meghalaya, Tamilnadu, Goa, Sikkim, Assam, Punjab, Delhi, Bihar,Jammu, Madhya Pradesh, Uttar Pradesh, Kashmir Etc.
Niksan Pharmaceutical is also large exporter ofthe API and finished pharmaceutical products of Clarithromycin in many countries for years. The countries where weexporting are Ireland, United Kingdom, Ghana, Philippines, Singapore, Jamaica,Pakistan, Kenya, Canada, Qatar, Jordan, Sri Lanka, Austria, Nigeria, Tanzania,Vietnam, Australia, United Arab Emirates, Oman, Kuwait , Hong Kong, Lebanon,Germany, Lithuania, United States, Iraq, Latvia, Malaysia, Saudi Arabia,Switzerland, Denmark, South Africa, Thailand, Bangladesh, New Zealand, Taiwan,Egypt, Greece, South Korea, Hungary, Israel, Bulgaria, Norway, Czechia, Iran,Indonesia, Belgium, China, Sweden, Netherlands, Poland, Spain, Mexico, Turkey,France, Japan, Italy, Brazil and many more countries.
Clarithromycin is simply given as an antibacterial drug.Clarithromycin belongs to the macrolide antibiotic which is used to prevent thegrowth of bacteria in infected place.
Clarithromycin is also given in the combinations to treat theGI ulcers and bacterial infections.
SYNONYMS OF CLARITHROMYCIN:6-O-methyl erythromycin, 6-O-methylerythromycin A, Clarithromycin,Clarithromycina, Clarithromycine, Clarithromycinum, Claritromicina.
IUPAC NAME:(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}-14-ethyl-12,13-dihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy}-7-methoxy-3,5,7,9,11,13-hexamethyl-1-oxacyclotetradecane-2,10-dione
CAS NO: 81103-11-9
FORMULA: C38H69NO13
MOLECULAR MASS: 747.95 g/mol
STORAGE CONDITIONS: Store in cool dry place away from directsun light. Do not keep container in humid or moist place like bathroom. Keepaway from children and pets.
HOW TO USE: Take medicine by mouth with or without food. Takemedicine 2 times per day. If you feel stomach upset take medicine with food ormilk. Take medication regularly to get more benefits.
HOW CLARITHROMYCINWORKS: Clarithromycin simply stops the growth of bacteria and by that it isused in the treatment of bacterial infections, pneumonia, skin infections,stomach ulcers etc.
PHARMACOKINETICS: Clarithromycin kills muchtype of gram positive and gram negative bacteria by destroying their cellwalls. Clarithromycin is well absorbed in body and also it is acid stableand bindswith almost 70% plasma protein. The half-life of Clarithromycin is between 3-4hours. The elimination of Clarithromycin is done by 20% by urine.
SIDE EFFECTSOF CLARITHROMYCIN: The normal side effects like vomiting, nausea, headache, and change intaste are common. If you see side effects like hearing loss, muscle weakness,stomach pain, eye pain, speaking problem, eye problem, tell you doctor aboutit. The medicine rarely causes intestinal problems when taken for long time.
PRECAUTIONS: Tell your doctor if youhave allergic reactions to the Clarithromycin or inactive ingredients. Clarithromycincan cause problem related to heart like hear beat problem, irregularheartbeats, and other problems like dizziness fainting. Kindly take yourdoctors advice if you see such kind of problem.
CDSCO APPROVAL: Combipack of Omeprazole + clarithromycin +amoxicillin tablet approved by CDSCO in Indian in 01.10.2002,
Clarithromycin tablets tablet approved by CDSCO in Indian in22.03.1995,
Combipack tablet approved by CDSCO in Indian in 09.09.1997,
Clarithromycin 1% gel approved by CDSCO in Indian in 12.06.2002,
Clarithromycin M.R tabs approved by CDSCO in Indian in 16.10.2001
FORMULATIONS AVAILABLE IN MARKET:
Clarithromycin 1%w/w cream
Clarithromycin 1%w/v gel
Clarithromycin250mg tablets
Clarithromycin 500mg tablets
Clarithromycin 125mg tablets
Clarithromycin 125mg/5ml solution
Clarithromycin 250mg/5ml solution
Omeprazole + Clarithromycin + amoxicillin tablets
Note: Product protected by valid patents are notoffered for sale in countries where such patents are still valid and itsliability is at Buyers Risk
REFERENCES:
www.webmd.com
https://pubchem.ncbi.nlm.nih.gov
https://go.drugbank.com
https://cdscoonline.gov.in
https://www.wikipedia.org/
https://www.drugs.com
https://www.zaubacorp.com
https://www.practo.com/consult
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