TENELIGLIPTIN

Product Description

Niksan Pharmaceutical is one of the leading manufacturer,supplier and exporter of the Teneligliptin.The best product manufactured by Niksan Pharmaceutical is Teneligliptin. We manufacture, supply and exportbest quality product of Teneligliptin API along with Teneligliptin formulations.

Niksan Pharmaceutical provides best quality product of Teneligliptin in all states of Indialike Kerala,Punjab, Rajasthan, Telangana, Bihar, Karnataka, Jammu and Kashmir, Maharashtra,West Bengal, Uttar Pradesh, Gujarat, Delhi, Tamil Nadu, Odisha, Madhya Pradesh,Andhra Pradesh, Haryana  and many otherstates.

Niksan Pharmaceutical is also manufacture and exports largequantity of Teneligliptin productsin whole globe since many years in countries like Nepal, United Arab Emirates,South Korea, Philippines, Bangladesh, Australia, United States, United Kingdom,Bulgaria, Burkina Faso, Burundi, Estonia, Eswatini, Ethiopia, Mauritius,Mexico, Micronesia, Moldova, Monaco, Mongolia, Montenegro, Morocco, Mozambique,Myanmar (Burma), Namibia, Nauru, , Georgia, Germany, Ghana, Greece, Grenada,Guatemala, Guinea, Guinea-Bissau, Guyana, Haiti, Honduras, Hungary, Iceland,Indonesia, Iran, Iraq, Ireland, Israel, Italy, Jamaica, Japan and Jordan,Kazakhstan, Kenya, Kiribati, North Korea, South Korea, Kosovo, Kuwait,Kyrgyzstan, Laos, Latvia, Lebanon, Lesotho, Liberia, Libya, Liechtenstein,Lithuania, Luxembourg, Madagascar, Malawi, Malaysia, Maldives, Mali, Malta,Marshall Islands, Mauritania, Peru, Philippines, Poland, Portugal, Qatar,Romania, Russia, Rwanda, Saint Kitts and Nevis, Saint Lucia, Saint Vincent andthe Grenadines, Cabot Verde, Cambodia, Cameroon, Nepal, Netherlands, NewZealand, Nicaragua, Niger, Nigeria, North Macedonia, Norway, Oman, Pakistan,Palau, Panama, Papua New Guinea, Paraguay, Fiji, Finland, France, Gabon, TheGambia Canada, Central African Republic, Chad, Chile, China, Colombia, Comoros,Democratic Republic of the Congo, Republic of the Congo, Costa Rica, Cote d’Ivoire,Croatia, Cuba, Cyprus, Czech Republic, Denmark, Djibouti, Dominica, DominicanRepublic, East Timor (Timor-Leste), Ecuador, Egypt, El Salvador, EquatorialGuinea, Eritrea, Samoa, San Marino, Sao Tome and Principe and Saudi Arabia andmany other countries.

Teneligliptin is one type ofanti-diabetic medication which is used in the treatment of type II diabetesmellitus. Teneligliptin is also called as DPP-4 inhibitors. Teneligliptin isgiven to the patient for control the risen blood sugar level.

SYNONYMS: Teneligliptin, DPP-4 inhibitor.

IUPAC NAME: 1-(3-methyl-1-phenyl-1H-pyrazol-5-yl)-4-[(3S,5S)-5-(1,3-thiazolidine-3-carbonyl)pyrrolidin-3-yl]piperazine

CAS NO: 760937-92-6

MOLECURAL FORMULA: C₂₂H₃₀N₆OS

MOLAR MASS: 426.58 g/mol

STORAGE CONDITIONS: Store in room temperature away from directheat and light. Do not put medication in humid place and in bathroom.

HOW TO USE: Take Teneligliptin tablet once a day with orwithout water. Also ask your doctor for advice if you have any confusion.

HOW TENELIGLIPTIN WORKS: Teneligliptin inhibits the DPP-4 whichdegrades the insulin in the body. By inhibiting the degradation of insulin, theglucose level in the body decreases and by this the Teneligliptin is used tocontrol the rising blood glucose level.

PHARMACOKINETICS OFTENELIGLIPTIN: In the ratsthe oral absorption of Teneligliptin done very fast. Teneligliptin reaches thehighest peak plasma concentration n 0.75-0.88hrs. The half-life o Teneligliptinis about 24.2hrs. About 65.6% of Teneligliptin metabolize and eliminatedthrough hepatic and renal pathways and the remaining Teneligliptin iseliminates through kidney.

SIDE EFFECTS OF TENELIGLIPTIN: Generally the patient’s uses this medicationdoes not have any serious side effects. But if you have some side effects likeheart failure, join pain, skin blisters, weight gain, swelling of ankles,problem in breathing tell your doctor immediately. It Teneligliptin prescribedwith other diabetic agents the blood glucose level can decrease which causeweakness, fainting, tiredness.

PRECAUTIONS: If you have disease related to heart,pancreas, kidney, liver tell your doctor before taking medication. Do not takealcohol while taking this medication it can cause low blood sugar level. Teneligliptincan cause blurred vision, sleepiness so don not operate any vehicle, and do notdo any heavy lifting if you are not sure.

CDSCO APPROVAL: Teneligliptin Hydro bromide Hydrate 20mgapproved by CDSCO in Indian in 18.05.2015.

FORMULATIONS AVAILABLE IN MARKET:

Teneligliptin 20mg tablets

Metformin 1000mg + Teneligliptin20mg tablets

Metformin 500mg+ Teneligliptin20mg tablets

Note: Product protected by valid patents are notoffered for sale in countries where such patents are still valid and itsliability is at Buyers Risk.

REFERENCES:

www.webmd.com

https://pubchem.ncbi.nlm.nih.gov

https://go.drugbank.com

https://cdscoonline.gov.in

https://www.wikipedia.org/

https://www.drugs.com

https://www.zaubacorp.com

https://www.practo.com/consult