PERMETHOL SODIUM

Product Description

is one of the biggest manufacturer, supplier, exporter and trader ofthe PERMETHOL SODIUMfinished formulations moreover Permethol Sodium API. Niksan Pharmaceutical is the huge manufacturer, exporter andsupplier of PERMETHOL SODIUMAPI and formulation situated in Ankleshwar, Gujarat,India.

NiksanPharmaceutical is the suppliers, manufacturer, exporters and trader of
Permethol Sodium inthedomestic level as well as the international market.

Niksan is anIndian based pharmaceutical company so it also supplies and manufactures the Permethol Sodium to allIndian states like Gujarat, Maharashtra, Punjab, Delhi, Tamilnadu, Goa, UttarPradesh, Karnataka, Jammu & Kashmir, West Bengal, Assam, Rajasthan, Hyderabad,Karnataka, Kerala, Madhya Pradesh, Manipur, Meghalaya, Mizoram, Nagaland,Orissa, Punjab and Haryana.  

NiksanPharmaceutical and Niksan group companies are exporters, suppliers andmanufacturers of the API and also Permethol Sodium formulations in many countries for manyyears. Niksan pharmaceutical currently exports Permethol Sodium API and Formulation to countries like NewZealand, Jordan, Belgium, United Kingdom, Australia, Italy, Ireland, Hong Kong,Morocco,, Portugal, France, South Africa, Philippines, Malaysia, Singapore,Israel, Greece, Saudi Arabia, Egypt, Taiwan, Netherlands, South Korea,Switzerland, Algeria, Pakistan, Canada, Vietnam, United States, Germany, Braziland many other countries.

PERMETHOLSODIUMalsoknown as sodium methylesculetin acetate, is a compound primarily used for itsanti-inflammatory and antioxidant properties, particularly in oral careproducts. It's found in toothpastes and mouthwashes to help reduce guminflammation and bleeding. 

IUPAC NAME: 2-(6-hydroxy-4-methyl-2-oxochromen-7-yl)oxy

CAS NO:95873-69-1. 

FORMULA:C₁₂H₉NaO₆

MOLECULAR MASS:  272.19 g/mol

STORAGE CONDITIONS:Store in a tightly closed container in acool, dry, and well-ventilated area. Protect from light, heat, and moisture.Keep away from strong oxidizing agents.

HOW TO USE:Apply to the affectedarea (hair or skin) as prescribed, typically once and left for a specifiedperiod (e.g., 10 minutes) before rinsing off. Avoid contact with eyes, nose,and mouth. A second application may be recommended after 7–10 days ifnecessary.

HOW PERMETHOLSODIUM WORKS:Permethol Sodium disrupts the sodium channel current in the nerve cellmembrane of parasites, leading to paralysis and death. It affects the nervoussystem of lice and scabies mites, making it an effective ectoparasiticide.

PHARMACOKINETICSOF PERMETHOL SODIUM:Minimal systemic absorption occurs after topical use. The compoundremains mostly localized on the skin or scalp and is eliminated primarilythrough hepatic metabolism and urinary excretion if absorbed.

SIDE EFFECTSOF PERMETHOL SODIUM:Common side effects may include itching, redness, burning, or stingingat the application site. Rarely, allergic reactions, respiratory irritation, orneurological effects (if ingested or absorbed in large quantities) may occur.

PRECAUTIONS:  Avoid eye contact; rinse thoroughly if exposed. Notrecommended for infants under 2 months of age. Use under medical supervision inpregnant or breastfeeding women. Use caution in individuals with allergies topyrethrins or chrysanthemums. Only for external use. Do not ingest.

CDSCOAPPROVAL:PermetholLotion 5% – Approved by CDSCO on 15.01.2012

FORMULATIONSAVAILABLE IN MARKET:

PermetholLotion 5%

 Permethol Cream 5%

PermetholShampoo 1%

Note: Productprotected by valid patents are not offered for sale in countries where suchpatents are still valid and its liability is at Buyers Risk

REFERENCES:

www.webmd.com

https://pubchem.ncbi.nlm.nih.gov

https://go.drugbank.com 

https://cdscoonline.gov.in 

https://www.wikipedia.org/

https://www.drugs.com

https://www.zaubacorp.com

https://www.practo.com/consult