LETRAZOLE

70000.00 INR/Kilograms

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Product Details:

Smell Other
Heavy Metal (%) does not contain
Particle Size 24 nm to 91 nm
Solubility practically insoluble in water, but freely soluble in dichloromethane, and slightly soluble in ethanol
Molecular Weight 285.30 g/mol Grams (g)
Structural Formula C17H11N5
Melting Point 181-185C
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LETRAZOLE Price And Quantity

Price 70000.00 INR/Kilograms
Minimum Order Quantity 1 Kilograms

LETRAZOLE Product Specifications

Taste Other
Usage Take the medicine orally once a day with or without food. Take medicine with milk or food if you feel stomach upset. Take medication regularly to get most benefits of it.
EINECS No 675-034-8
Molecular Formula C17H11N5
Type Pharmaceutical Intermediates
Storage Room Temperature
HS Code 3004.90
Boiling point 374.4 C
Appearance dark yellow
Ph Level (7.4)
Loss on Drying not have a specific
Physical Form Powder
Shelf Life 3 Years
Particle Size 24 nm to 91 nm
Purity(%) 98.0%
Heavy Metal (%) does not contain
Medicine Name LETRAZOLE
Smell Other
Grade Other
Chemical Name 4-[(4-cyanophenyl)(1H-1,2,4-triazol-1-yl)methyl]benzonitrile
Melting Point 181-185C
CAS No 112809-51-5
Structural Formula C17H11N5
Solubility practically insoluble in water, but freely soluble in dichloromethane, and slightly soluble in ethanol
Molecular Weight 285.30 g/mol Grams (g)

LETRAZOLE Trade Information

FOB Port SAHAR AIR CARGO
Payment Terms Cash Advance (CA), Cheque
Supply Ability 100 Kilograms Per Month
Delivery Time 1 Days
Sample Available No
Packaging Details Double LDPE Liners in HDPE carboys
Main Domestic Market All India
Certifications FDCA, GMP, GLP AND ISO

Product Description

Letrozole belongs to aromatase inhibitors class ofmedicine. Letrozole works by stopping the growth of breast cancer cell whichneeds estrogen to grow. Letrozole inhibits the estrogen level in body.

SYNONYSMS: Letrozole, Letrozol

IUPAC NAME:4-[(4-cyanophenyl)(1H-1,2,4-triazol-1-yl)methyl]benzonitrile

CAS NO: 112809-51-5

FORMULA: C₁₇H₁₁N₅

MOLECULAR MASS: 285.30 g/mol

STORAGE CONDITIONS: Store the medicine in room temperature and dry place. Placethe medication away from direct heat and light. Do not keep medicine inbathroom or humid place. Keep away from children and pets.

HOW TO USE: Take themedicine orally once a day with or without food. Take medicine with milk orfood if you feel stomach upset. Take medication regularly to get most benefitsof it.

HOW LETROZOLE WORKS: Letrozole blocks the active site ofelectron transfer chain of CYP19A1. By this Letrozole inhibits the conversionof estrogen form androgen. By this Letrozole stops the growth of cancer cellswhich needs estrogen to grow.

PHARMACOKINETICS: Letrozole absorbed rapidly in body afteroral administration. Letrozole takes 8.10hpurs to reach peak plasmaconcentration. The bioavaibility of Letrozole is 99.9%. Almost 60% of medicinebinds with the plasma proteins. The half-life of this medicine is 42hours. Almost90% of Letrozole eliminated through urine.

SIDE EFFECTS OF LETROZOLE: The common side effects of Letrozole areheadache, nausea, vomiting, dizziness, sweating, tiredness, joint and musclepain. Tell your doctor if you see side effects like hot flushes, hair loss,bone fracture, swelling of arms or feet, blurred vision, dark urine. Seekimmediate medical attention if you see side effects like blood in cough,shortness of breath, arm or leg pain, stomach pain, dizziness, fainting, hairloss, vision change and sudden headache.

PRECAUTIONS: Tell your doctor if you have allergicreaction to the Letrozole medicine.

Tell your doctor if youhave history like heart disorder, liver problem, high BP, strokes, blood clotproblems. This drug makes you dizzy and because blurred vision so kindly avoiddriving, exercise, and operating machineries. Do not consume alcohol ormarijuana while taking the medicine.

CDSCO APPROVAL:LapatinibDitosylate Tablets 250mg (addl. Indication) approved by CDSCO in India in 10.05.2010
Letrozole 2.5mg tablet (additional indication) approved by CDSCO in India in28.12.2004

Letrozole approved by CDSCOin India in 11.02.2002

Palbociclib Capsules75mg/100mg/125 mg approved by CDSCO in India in11.08.2016

Letrozole tabs approved byCDSCO in India in12.03.1998

Letrozole 2.5mg tablet (for additional indication)approved byCDSCO in India in 10.04.2007

FORMULATIONS AVAILABLE IN MARKET:

Letrozole 5mg tablets

Letrozole 2.5 mgtablets

Note: Product protected by valid patents are notoffered for sale in countries where such patents are still valid and itsliability is at Buyers Risk

REFERENCES:

www.webmd.com

https://pubchem.ncbi.nlm.nih.gov

https://go.drugbank.com

https://cdscoonline.gov.in

https://www.wikipedia.org/

https://www.drugs.com

https://www.zaubacorp.com

https://www.practo.com/consult

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Email : info@niksanpharmaceutical.com

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