Product Description

Niksan Pharmaceutical is one of the leading manufacturer,supplier and exporter of the Miconazole Nitrate. The best product manufactured by Niksan Pharmaceutical is Miconazole Nitrate. We manufacture, supply and export best quality product of Miconazole Nitrate API alongwith Miconazole Nitrate formulations. 

Niksan Pharmaceutical is the largest manufacturer, trader and supplier and exporter of Miconazole Nitrate in all-over Ankleshwar, Gujarat, India.

NiksanPharmaceutical manufactures and supplies the Miconazole Nitrate product to the Indian states like Maharashtra, Meghalaya, Tamilnadu, Kerala, Gujarat,Goa, Sikkim,Assam, Punjab, Delhi, Bihar, Karnataka, Haryana, Rajasthan, Madhya Pradesh,Uttar Pradesh, Rajasthan, Karnataka, and other states.

Congo,Philippines, Colombia and Germany, Cyprus, Nigeria, Rwanda, South Africa,Denmark, Slovenia, Bolivia, Japan, Uganda, Uzbekistan, Cameroon, Netherlands,Azerbaijan, Venezuela, Morocco, Cote D Ivoire, Turkey, Pakistan, Slovenia,Ireland, Zambia, Poland, Hungary, Ireland, Austria, St Lucia,South Korea, Malawi, Croatia, Malta, Kazakistan, Indonesia, Vietnam, Australia,Hungary, Finland, Sweden, Canada, Australia, United kingdom, Ukraine, Russia, France andmany more countries. 

Miconazole Nitrate belongs to the class called azoles. Miconazole Nitrate is the medicine used to prevent the fungal infections. Miconazole Nitrate is used as an antifungal agent to treat the fungal infection on vagina and skin 

SYNONYMS: Miconazol, Miconazole,Miconazolum

IUPAC NAME: 1-{2-[(2, 4-Dichlorobenzyl) oxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole nitrate

CAS NO: 22832-87-7

FORMULA: C₁₈H₁₅Cl₄N₃O₄

MOLECULAR MASS: 479.1 g/mol 

STORAGE CONDITIONS: Store the medicine in cool and dry place, away from direct light and heat.Do not place medicine in bathroom or any humid place. Do not put the cap open. Keep away from children and pets. 

HOW TO USE: Wash and dry the part of skin where this cream has to apply. Apply this medicine 2 times per day. If you use Miconazole spray,kindly shake the container before using it. 

HOW MICONAZOLE WORKS: Miconazole works by inhibiting the CYP450 anzyme which is used to build the fungal cell wall. By the inhibition of synthesis of cell wall, the fungal growth stops and by this Miconazole kills the fungal cells. 

PHARMACOKINETICS: Miconazole have poor absorption in the systemic circulation.  Miconazole takes 18.4 hours to reach the peak plasma concentration. Miconazole metabolism occurs in liver and it does not affect any other activity. The half-life of Miconazole is 24 hours. Less than 1% of Miconazole recovered in urine. And the elimination of Miconazole had done by both urine and feces. 

SIDE EFFECTS: Side effects like swelling, redness, itching, irritation of skin, burning are caused by Miconazole. If you see side effects like open sores, blistering of skin, contact your doctor. Seek immediate doctor attention if you see side effects like rash, swelling of skin, Redness,trouble in breathing and dizziness. 

PRECAUTION: Tell your doctor if you have any allergic reaction to Miconazole. Before taking the medication tell your doctor about your medical history. Do not take medication if you are in pregnancy or lactation period

CDSCO APPROVAL: Miconazole Nitrate approved by CDSCO in India in 1979-March,

Miconazole Nitrate approved by CDSCO in India in 1975-August,

Nadifloxacin (1%) + Miconazole Nitrate (2%) + Mometasone Furoate(0.1%) Cream approved by CDSCO in India in 06.06.2006,

Miconazole Nitrate approved by CDSCO in India in 1978-June.

FORMULATION AVAILABLE IN MARKET:
Miconazole Nitrate 2%w/w cream

Miconazole Nitrate 2%w/v gel

Miconazole Nitrate 200mg tablets

Miconazole Nitrate 100mg tablets

Nadifloxacin (1%) + Miconazole Nitrate (2%) + Mometasone Furoate(0.1%) Cream

Gentamycin 0.1% w/w +Miconazole 2%w/w cream

Gentamycin 0.1% w/v + Miconazole 2%w/v creamgel

Note: Product protected by valid patents are not offered for sale in countries where such patents are still valid and its liability is at Buyers Risk

REFERENCES: 

www.webmd.com

https://pubchem.ncbi.nlm.nih.gov

https://go.drugbank.com

https://cdscoonline.gov.in

https://www.wikipedia.org/

https://www.drugs.com

https://www.zaubacorp.com

https://www.practo.com/consult