METHYL PREDNISOLONE

Product Description

Niksan pharmaceutical is one of the leading manufacturer, supplier and exporter of the Methylprednisolone. The best antiproduct manufactured by Niksan Pharmaceutical is Methylprednisolone.  We manufacture, supply and export bestquality product of Methylprednisolone API along with Methylprednisoloneformulations.

NiksanPharmaceutical is also manufacture and exports large quantity of Methylprednisolone products inwhole globe since many years in countries like Indonesia, Puerto Rico, UnitedStates, Sri Lanka, Philippines, Taiwan, United Arab Emirates, Saudi Arabia,Australia, Vietnam Bangladesh, South Korea, Singapore, New Zealand, Canada,Malaysia, Belgium, Pakistan, Ireland, Iran, United Kingdom, Greece, Thailand,France, Egypt, Netherlands, Turkey, Mexico, Germany, Italy and many morecountries.

Niksan Pharmaceutical provides best quality product of Methylprednisolone in all states ofIndia like Kerala,Punjab, Rajasthan, Telangana, Uttar Pradesh, Gujarat, Delhi, Tamil Nadu, Bihar,Karnataka, Jammu and Kashmir, Maharashtra, West Bengal, Odisha, Madhya Pradesh,Andhra Pradesh, Haryana  and many otherstates.

Methylprednisolone is one type of anti-inflammatory drug. Methylprednisolonebelongs to the medicine class called corticosteroids. Methylprednisolone usedin the condition like cancer, blood disorders, arthritis, eye infections andmany more.

SYNONYMS: Methylprednisolon,Methylprednisolone, Methylprednisolonum, Metilprednisolona

IUPAC NAME: (1R,3aS,3bS,5S,9aR,9bS,10S,11aS)-1,10-dihydroxy-1-(2-hydroxyacetyl)-5,9a,11a-trimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-one

CAS NO: 83-43-2

FORMULA: C₂₂H₃₀O₅

MOLECULAR WEIGHT: 374.47 g·mol−1

STORAGE CONDITIONS: Store in cool and dry place. Keep away fromdirect hear or sin light. Do not put medicine in bathroom or kitchen. Keep awayfrom children.

HOW TO USE: Take medication by mouth with or withoutfood. Take medication one time per day. To get most benefits take medicationregularly.

HOW METHYLPREDNISOLONE WORKS: Methylprednisoloneworks by inhibiting the vasodilation of capillaries, and also decrease themigration of leukocytes to the site of inflammation. And by this activityMethylprednisolone gives anti-inflammatory effects.

PHARMACOKINETICS: Methylprednisolone absorbed rapidly afterthe oral administration. Methylprednisolone gives about 89-90% of bioavaibility.75-78% of Methylprednisolone binds with the plasma protein. The half-life ofMethylprednisolone is 2.3hours. The elimination of Methylprednisolone is doneby urination.

SIDE EFFECTS: The common side effects ofMethylprednisolone are nausea, vomiting, trouble in sleeping; hear burnheadache, sweating and loss of appetite. Methylprednisolone cause bloodpressure rise that can worsen the diabetes.

Methylprednisoloneincrease thirst and urination. Tellyour doctor if you see side effect like fever, sore throat, cough, chills.

PRECAUTIONS: Tell your doctor if you have any allergicreaction to the Methylprednisolone. Tell your doctor if you haveproblem like blood clots, bitter bones, eye disease, high blood pressure,stomach problems, abdominal problem. This drug makes you dizzy so do not do anyactivity like driving, exercise, or operating machineries.

CDSCO APPROVAL: Clotrimazole (10mg) + Methylprednisolone Acrponate 1mg/gm ofcream approved by CDSCO in India in 12.07.2007,

Mupirocin (2%) + Methylprednisolone Acrponate (0.1%) Creamapproved by CDSCO in India in 31.10.2007,

 Methylprednisoloneaceponate-1mg + Mupirocin-20mg cream approved by CDSCO in India in 21.11.2007,

Methylprednisolone approved by CDSCO in India in 1978-March,

 Methylprednisolone acetateapproved by CDSCO in India in 1962- November,

 Methylprednisolone Tablet8mg approved by CDSCO in India in 01.09.2009,

Methylprednisolone Acrponate topical solution 0.1% approved byCDSCO in India in 09.04.2007

FORMULATION AVAILABLE IN MARKET:

Methylprednisolone 4mg tablets

Methylprednisolone 8mg tablets

Methylprednisolone 1mg tablets

Methylprednisolone 40mg/ml solution

Methylprednisolone 16 mg tablets

Methylprednisolone 2mg tablets

Methylprednisolone 10 mg tablets

Methylprednisolone 24mg tablets

Methylprednisolone 125mg tablets

Methylprednisolone 500mg tablets

Methylprednisolone 250mg tablets

Methylprednisolone 0.1%w/w cream

Methylprednisolone aceponate-1mg +Mupirocin-20mg tablets

Note: Product protected by valid patents are notoffered for sale in countries where such patents are still valid and itsliability is at Buyers Risk

REFERENCES:

www.webmd.com

https://pubchem.ncbi.nlm.nih.gov

https://go.drugbank.com

https://cdscoonline.gov.in

https://www.wikipedia.org/

https://www.drugs.com

https://www.zaubacorp.com

https://www.practo.com/consult