GLICLAZIDE

6500 INR/Kilograms

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Product Details:

Shelf Life 3 Years
Molecular Formula C15H21N3O3S
EINECS No 244-260-5
Structural Formula C15H21N3O3S
Molecular Weight 323.412 g/mol Grams (g)
Heavy Metal (%) NMT 0.5%
Storage Room Temperature
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GLICLAZIDE Price And Quantity

Price 6500 INR/Kilograms
Minimum Order Quantity 1 Kilograms

GLICLAZIDE Product Specifications

Melting Point 163C to 169C
Storage Room Temperature
Appearance white or almost-white powder
Heavy Metal (%) NMT 0.5%
Molecular Weight 323.412 g/mol Grams (g)
Structural Formula C15H21N3O3S
EINECS No 244-260-5
Usage Gliclazide is a medicine known as a sulfonylurea. Sulfonylureas increase the amount of insulin your pancreas makes. This lowers your blood sugar.Gliclazide is treat 2 type diabetes
Molecular Formula C15H21N3O3S
Grade Medicine Grade
Shelf Life 3 Years
CAS No 21187-98-4
Taste Other
Particle Size less than 30 microns
Smell Other
Loss on Drying should not exceed 2.5 mg/g
Type Other
Solubility practically insoluble in water
Chemical Name N-[[(hexahydrocyclopenta[c]pyrrol-2(1H)-yl)amino]carbonyl]-4-methylbenzenesulfonamide
Medicine Name GLICLAZIDE
Ph Level acidic (pH 1.2) and alkaline (pH 7.2)
Physical Form Powder
Purity(%) 99%
Boiling point Not available
HS Code 293590900000

GLICLAZIDE Trade Information

FOB Port INDIA
Payment Terms Cash Advance (CA), Cheque
Supply Ability 100 Kilograms Per Month
Delivery Time 1 Days
Packaging Details HDPE DRUM WITH TWO INNER LDPE LINNER
Main Export Market(s) South America, Eastern Europe, Western Europe, Middle East, Africa, Asia, Australia, Central America, North America
Main Domestic Market All India
Certifications GMP, FDCA

Product Description

is one of the biggest manufacturer, supplier, exporter and trader ofthe GLICLAZIDEfinished formulations moreover Gliclazide API. Niksan Pharmaceutical is the huge manufacturer, exporter andsupplier of Gliclazide API and formulation situated in Ankleshwar, Gujarat, India.

NiksanPharmaceutical is the suppliers, manufacturer, exporters and trader of
Gliclazide inthedomestic level as well as the international market.

Niksan is anIndian based pharmaceutical company so it also supplies and manufactures the Gliclazide to allIndian states like Gujarat, Maharashtra, Punjab, Delhi, Tamilnadu, Goa, UttarPradesh, Karnataka, Jammu & Kashmir, West Bengal, Assam, Rajasthan,Hyderabad, Karnataka, Kerala, Madhya Pradesh, Manipur,Meghalaya, Mizoram, Nagaland, Orissa, Punjab and Haryana.

NiksanPharmaceutical and Niksan group companies are exporters, suppliers andmanufacturers of the API and also Gliclazide formulations in many countries for many years. Niksanpharmaceutical currently exports Gliclazide API and Formulation to countries like New Zealand, Jordan,Belgium, United Kingdom, Australia, Italy, Ireland, Hong Kong, Morocco,Portugal, France, South Africa, Philippines, Malaysia, Singapore, Israel,Greece, Saudi Arabia, Egypt, Taiwan, Netherlands, South Korea, Switzerland,Algeria, Pakistan, Canada, Vietnam, United States, Germany, Brazil and manyother countries.

GLICLAZIDEis an oralantihyperglycemic agent, specifically categorized as a sulfonylurea.It isused to treat type 2 diabetes by stimulating the pancreas to release moreinsulin.Furthermore, gliclazide is classified as a second-generationsulfonylurea, alongside other drugs like glibenclamide and glipizide.Italso falls under theBCS Class II drug categorydue to its lowsolubility and high permeability.

SYNONYSMS:Glimicron, Gliclazida, Diamicron

IUPAC NAME: 1-(3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-2-yl)-3-(4-methylphenyl)sulfonylurea

CAS NO:21187-98-4

FORMULA:C15H21N3O3S

MOLECULAR MASS: 323.412g/mol

STORAGE CONDITIONS:Store this medication atroomtemperature between 59 and 86 degrees F (15 and 30 degrees C) away from heat,light and moisture. Do not store in the bathroom. Keep this and all medicationsout of the reach of children. MEDICAL ALERT: Your condition can causecomplications in a medical emergency.

HOW TO USE:Swallow yourgliclazide tablets whole with a drink of water. Do not chew them. If you aretaking 2 doses a day, take 1 dose with your breakfast and 1 dose with yourevening meal. If you are taking slow-release gliclazide, take your dose once aday with breakfast.

HOW GLICLAZIDEWORKS:Gliclazide, asulfonylurea,helps lowerblood sugar in people withtype 2 diabetesbystimulatingthe pancreas to release more insulin.It also improves the bodyssensitivity to insulin, making it more effective at controlling glucoselevels.Essentially, it helps the body use insulin more efficiently andeffectively.

PHARMACOKINETICSOF GLICLAZIDE:Gliclazide is a sulphonylurea drug with anintermediate half-lifeof around 11 hours. It is extensively metabolised, and renal clearance accountsfor only 4% of total drug clearance. The molecule contains an azabicyclo-octylgroup which confers special properties on the basic sulphonylurea moiety.

SIDE EFFECTSOF GLICLAZIDE:Stomach ache or indigestion, Feeling sick (nausea) , Being sick(vomiting), frequent sips of water or squash to avoid dehydration, Diarrhoea, Drinklots of fluids, Constipation.

PRECAUTIONS: Tell yourdoctor if you are allergic to the medicine. Ask your doctors advice if youhave medical history like diabetes, heart problem, liver problem, kidney disease,breast cancer or tumour. If you are taking the other medication kindly tellyour doctor about it. Avoid combination with alcohol, Dont Take This Medicine During Pregnancy& Breast-Feeding.

CDSCOAPPROVAL:

Gliclazide modified release tablet 14.08.07

Gliclazide tablets 1988-November

Gliclazide modified release tabs. 09.11.2000

Gliclazide M.R. (30mg/60mg) + Metformin HCl (500mg) ER Tablet27/04/2005

Gliclazide 40mg/80mg + MetFormin Hcl 500mg + Rosiglitazone 2mgtablet 22/08/2006

Metformin SR 500mg/500mg + GliclazideSR 60mg/30mg + Pioglitazone15mg/15mg tablets 28.05.10

Gliclazide 40/80mg+Metformin 500mg+Pioglitazone15mg 19.07.10

FORMULATIONSAVAILABLE IN MARKET:

GLICLAZIDE 30 MG tablets

GLICLAZIDE 40 MG tablets

GLICLAZIDE 60 MG tablets

GLICLAZIDE 80 MG tablets

Note: Productprotected by valid patents are not offered for sale in countries where suchpatents are still valid and its liability is at Buyers Risk

REFERENCES:

www.webmd.com

https://pubchem.ncbi.nlm.nih.gov

https://go.drugbank.com

https://cdscoonline.gov.in

https://www.wikipedia.org/

https://www.drugs.com

https://www.zaubacorp.com

https://www.practo.com/consult

Mechanism of Action

Gliclazide belongs to the sulfonylurea class of antidiabetic drugs. It functions by encouraging the pancreas to produce more insulin, which helps reduce elevated blood glucose levels in patients with type 2 diabetes. Its effectiveness has made it a staple in diabetes care regimens globally.

Quality and Specifications

The medicine presents as a powder with high purity (99%) and controlled particle size (under 30 microns). It should contain less than 2.5 mg/g loss on drying and heavy metals must not exceed 0.5%. For optimal efficacy, Gliclazide should be stored at room temperature and used within its three-year shelf life.

FAQs of GLICLAZIDE:

Q: How does Gliclazide help manage type 2 diabetes?

A: Gliclazide promotes the pancreas to increase insulin production, which lowers blood sugar levels effectively in individuals with type 2 diabetes. This process enables better glycaemic control and error reduction in long-term diabetes management.

Q: What is the best way to store Gliclazide powder?

A: Gliclazide should be stored at room temperature in a dry, well-ventilated area. Avoid exposure to excessive moisture and heat to maintain its stability and prolong its shelf life of three years.

Q: When should Gliclazide be used during diabetes treatment?

A: Gliclazide is typically prescribed when diet, exercise, and lifestyle changes alone are insufficient to control blood sugar. Your doctor will determine the appropriate timing based on your individual health profile.

Q: Where is Gliclazide manufactured and supplied?

A: Gliclazide is manufactured, distributed, and supplied by licensed companies across India, including exporters, importers, and traders who adhere to stringent quality standards for pharmaceutical products.

Q: What are the physical and chemical properties of Gliclazide?

A: Gliclazide is a white or near-white powder, with a molecular weight of 323.412 g/mol. It is practically insoluble in water, has an acidic and alkaline pH range (1.2 and 7.2), and a melting point between 163C and 169C.

Q: What benefits does Gliclazide offer over other diabetes medicines?

A: Gliclazide offers a rapid onset of action, reliable purity, and strict quality controls, such as limited loss on drying and heavy metal content, which makes it a preferred choice among sulfonylurea medications.

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Plot No. 4706/03, Gidc Estate, SF-12, Shrinathji Arcade, Near Meghmani Chowkadi,Ankleshwar - 393002, Gujarat, India
Phone :91--9537871777
Email : info@niksanpharmaceutical.com

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Mr SANJAY PATEL (SALES DEPARTMENT)
Mobile :+919537871777
info@niksanpharmaceutical.com
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