Product Description

Niksan Pharmaceutical is words top leading manufacturer, exporter, trader and supplier of Drotaverine API as well as finished pharmaceutical products of Drotaverine among the pharmaceutical companies. Our product Drotaverine is widely used and appreciated by our group companies and also our customers and users all around the nations. We offer the Drotaverine in very affordable price.

Niksan Pharmaceutical provides API and finished formulations of Drotaverine in allover Indian states Like Kerala, Gujarat, Haryana, Rajasthan, Madhya Pradesh,Uttar Pradesh, Rajasthan, Karnataka, Meghalaya, Tamilnadu, Goa, Sikkim, Assam,Punjab, Delhi, Bihar, Jammu Kashmir Etc.

Niksan Pharmaceutical is also large exporter of the API and finished pharmaceutical products of Drotaverine in many countries for years. The countries where we exporting are Myanmar (Burma), Nepal, Afghanistan, Uganda, Ghana, Yemen,Pakistan, Syria, Lithuania, Vietnam, Iraq, Nigeria, Thailand, Malaysia,Hungary, Romania, Egypt, Bolivia, Ukraine, Poland, United Kingdom, Mexico, Russia, Germany, Canada, Turkey, United States, Spain, France and many more countries.

Drotaverine is one type of anti-spasmodic drug. Drotaverine is the posphodiesterase 4 inhibitor.

Drotaverine used to enhance the cervical dilation during the birth process. Drotaverine also treat the spasm and twitches the smooth muscle of the stomach. 

SYNONYMS OF DROTAVERINE: Drotaverin, Drotaverina,Drotaverine, Drotaverinum. 

IUPAC NAME: (1Z)-1-[(3, 4-diethoxyphenyl)methylidene]-6, 7-diethoxy-1, 2, 3, 4-tetrahydroisoquinoline. 

CAS NO:14009-24-6 

FORMULA:C₂₄H₃₁NO₄ 

MOLECULAR MASS: 397.50 g/mol 

STORAGE CONDITIONS: Store in room temperature in dry place. Do not put it in bathroom or fridge. Keep away from direct light and heat. Keep away from children and pet. 

HOW TO USE: Take the medicine orally with or without food. If you have any confusion regarding to the medication ask your doctor. Take medication regularly to achieve maximum benefits from it. 

HOW DROTAVERINEWORKS: Drotaverine is anti-spasmodic drug which inhibits the phosphodiesterase4 enzyme and by this it cause vasodilation of the cervical muscle whiles the birth process. It is also used in the treatment of headache and syndrome. 

PHARMACOKINETICS: Drotaverine inhibits the phosphodiesterase 4 enzyme and increase the cAMP concentration. The bioavaibility of Drotaverine is variable. About 80-95% the Drotaverine drug binds with the plasma protein. The half-life of Drotaverine is between 7-12hrs. The  elimination of the Drotaverine is done mainly by the bile. 

SIDE EFFECTS: The side effects of Drotaverine are nausea, vomiting, swelling of face, lips, tongue. Drotaverine also cause dry mouth, change in pulse rate, Dizziness, headache. 

PRECAUTIONS: Tell your doctor if you have allergic reaction from the Drotaverine. If you have past disease like liver disease, kidney problem or heart related problem kindly consult and tell your doctor. Do not take alcohol or marijuana while taking the medication. Do not overdose the medication it can cause many side effects. 

CDSCO APPROVAL: Drotaverine + Aceclofenac (80mg+ 100mg) Tablets approved by CDSCO in Indian in 15.09.2008.

FORMULATIONSAVAILABLE IN MARKET:

Drotaverine 40mg tablets

Drotaverine 80mg tablets

Drotaverine 40mg/2ml oral solution

Drotaverine 20mg/5ml oral solution

Drotaverine 10mg/5ml oral solution

Drotaverine 80mg + Diclofenac 50mg tablets

Drotaverine 40mg + Nimesulide 100mg tablets

Drotaverine 80mg + Aceclofenac100mg tablets

Note: Product protected by valid patents are not offered for sale in countries where such patents are still valid and its liability is at Buyers Risk

REFERENCES:

www.webmd.com

https://pubchem.ncbi.nlm.nih.gov

https://go.drugbank.com

https://cdscoonline.gov.in

https://www.wikipedia.org/

https://www.drugs.com

https://www.zaubacorp.com

https://www.practo.com/consult