LORNOXICAM

Product Description

is leading manufacturer and distributer of the Lornoxicam among the other countries. Niksan Pharmaceutical is oneof the major the supplier, distributer, exporter and manufacturer of the Lornoxicam API andfinished formulations in Ankleshwar, Gujarat, India. The products of NiksanPharmaceutical and Niksan group companies are widely appreciated by the clientsand other companies.

Niksan Pharmaceutical is the supplier,manufacturer, exporter and trader of Lornoxicam in the domestic level as well as the internationalmarket. 

Niksan Pharmaceutical provides Lornoxicam API in allover Indian states like Jammu & Kashmir, Himachal Pradesh, Uttarakhand,Punjab, Kerala, Chandigarh, Chhattisgarh, Andhra Pradesh, Rajasthan, Meghalaya, Mizoram,Nagaland, Orissa,, Dadra and NagarHaveli, Goa, Gujarat,Jharkhand, West Bengal, Karnataka, Kerala, Madhya Pradesh etc.

Niksan Pharmaceutical also provides Lornoxicam API and finished formulations in all othercountries of the world like Germany, Switzerland, Poland, Latvia, Egypt,Lithuania, Estonia, Ukraine, Moldova, Russia, United States, Austria, Belarus,Serbia, India, Spain, Slovenia, Nigeria, Croatia, South Africa, Kazakhstan,Italy, Romania, Bulgaria, Portugal, South Korea, Greece, Philippines, Belgium,Saudi Arabia, Turkey, Japan etc.

Lornoxicam (chlortenoxicam) is a new nonsteroidalanti-inflammatory drug (NSAID) of the oxicam class withanalgesic, anti-inflammatory and antipyretic properties.

SYNONYMS: Chlortenoxicam,Lornoxicam, Lornoxicamum

IUPAC NAME: 6-chloro-4-hydroxy-2-methyl-1,1-dioxo-N-(pyridin-2-yl)-2H-1λ⁶-thieno[2,3-e][1,2]thiazine-3-carboxamide

CAS NO: 70374-39-9

FORMULA: C₁₃H₁₀ClN₃O₄S₂

MOLECULAR MASS:371.81 g/mol

STORAGE OF LORNOXICAM:Nospecial storage conditions are required.

APPLICATIONS OF LORNOXICAM:LORNOXICAM is used to reduce and relieve pain and inflammation (swelling) inosteoarthritis and rheumatoid arthritis. LORNOXICAMworks by blocking the effect of a chemical messenger known as cyclo-oxygenase(COX) enzyme that makes other chemical prostaglandins.

HOW TO USE: It should be taken with food or milk to avoid getting anupset stomach. It can cause serious complicationslike stomach bleeding and kidney problems if taken for a long time. Lornoxicamcan raise your risk of blood clots, heart attack, or a stroke.HOW LORNOXICAM WORKS: LORNOXICAM isused to reduce and relieve pain and inflammation (swelling) in osteoarthritisand rheumatoid arthritis. LORNOXICAM works by blocking the effect of a chemicalmessenger known as cyclo-oxygenase (COX) enzyme that makes other chemicalprostaglandins.

CONTRAINDICATIONS OF LORNOXICAM: The drug is contraindicated in patients who must not takeother NSAIDs, possible reasons including salicylate sensitivity,gastrointestinal bleeding and bleeding disorders, and severe impairment ofheart, liver or kidney function.

PHARMACOKINETICS OF LORNOXICAM: Lornoxicam is eliminatedfollowing biotransformation to 5'-hydroxy-lornoxicam, which does not undergoenterohepatic recirculation. Glucoroconjugated metabolites are excreted in urine andfaeces with a half-life of about 11 hours.Lornoxicam and its metabolites bind extensively to plasma albumin.

SIDE EFFECTS OF LORNOXICAM:  Allergic reaction like fever, chills, rash,hives, breathing difficulty, swelling over your face, lips, throat,running/stuffy nose and sneezing, Swelling (inflammation) of the intestine, Diarrhea,nausea, vomiting and indigestion, Blood disorders, Vision trouble, sensitivityto light.

PRECAUTIONS: Consult your doctor ifyou are pregnant or breastfeeding. LORNOXICAM should not be taken during the last threemonths of pregnancy. LORNOXICAM may cause dizziness,so drive only if you are alert. LORNOXICAM is not recommended for childrenbelow 18 years as safety has not been established.

CDSCO APPROVAL:

Lornoxicam tablet 4mg/ 8mg are approvedby CDSCO in India in 21.05.07

FORMULATION AVAILABLEIN MARKET:

Lornoxicam 4MG

Lornoxicam 4MG+Paracetamol 325 MG

Lornoxicam 8MG + Peracetamol 325 MG

Lornoxicam 8MG + Peracetamol 500 MG

Lornoxicam 8MG + Thiocholchicoside 4 MG

Lornoxicam 8MG + Thiocholchicoside 8MG

Lornoxicam 8MG + Thiocholchicoside 8MG

Lornoxicam 8MG+Paracetamol 325 MG+Trypsin-Chymotrypsin 150000 AU

Lornoxicam 8MG+Paracetamol 500 MG+Serratiopeptidase 15 MG

Lornoxicam16 MG

Lornoxicam SR16mg Tabs

Lornoxicam12 mg SR

Lornoxicam8mg /2ml inj

Lornoxicam4mg + Eperisone 50mg tablet

ThiocolchicosideIP 8/16mg + Lornoxicam 8/16mg

LornoxicamER Tablet 8 mg

Lornoxicaminjection

Lornoxicam4mg + Paracetamol 500mg film coated tablets

Lornoxicam4mg/4mg + Thiocolchicoside 4mg/8mg tablets

Lornoxicamtablet 4mg/ 8mg

Lornoxicam8mg/8mg + Thiocolchicoside 4mg/8mg Tablets

Note: Product protected by validpatents are not offered for sale in countries where such patents are stillvalid and its liability is at Buyers Risk

REFERENCES:

www.webmd.com

https://pubchem.ncbi.nlm.nih.gov

https://go.drugbank.com

https://cdscoonline.gov.in

https://www.wikipedia.org/

https://www.drugs.com

https://www.zaubacorp.com

https://www.practo.com/consult