LAFUTIDINE .

170000 INR/Kilograms

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Product Details:

Molecular Weight 431.54 g/mol Grams (g)
Boiling point 704.2 C
Solubility freely soluble in glacial acetic acid, methanol, and DMF, and sparingly soluble in dehydrated ethanol
Taste Other
Structural Formula C22H29N3O4S
HS Code 29420090
Storage Room Temperature
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LAFUTIDINE . Price And Quantity

Price 170000 INR/Kilograms
Minimum Order Quantity 1 Kilograms

LAFUTIDINE . Product Specifications

Boiling point 704.2 C
Molecular Weight 431.54 g/mol Grams (g)
Physical Form Powder
Type Pharmaceutical Intermediates
Solubility freely soluble in glacial acetic acid, methanol, and DMF, and sparingly soluble in dehydrated ethanol
Chemical Name N-(4-(4-piperidinylmethyl)pyridyl-2-oxy)butenyl-2-(furfurylsulfinyl)acetamide
Usage in the treatment of gastroesophageal reflux disease (acid reflux) and peptic ulcer disease
Taste Other
HS Code 29420090
Structural Formula C22H29N3O4S
Heavy Metal (%) under 0.1%
Loss on Drying not more than 1.0%
Molecular Formula C22H29N3O4S
Storage Room Temperature
Purity(%) 98.0%
CAS No 118288-08-7
Particle Size D90 less than 10 microns
Smell Other
Shelf Life 3 Years
Appearance yellowish-white
Grade Medicine Grade
EINECS No 601-513-8
Melting Point between 96 and 101C
Ph Level >3 and >4
Medicine Name LAFUTIDINE

LAFUTIDINE . Trade Information

FOB Port INDIA
Payment Terms Cash Advance (CA), Cheque
Supply Ability 100 Kilograms Per Week
Delivery Time 1 Days
Packaging Details HDPE DRUM WITH TWO INNER LDPE LINER
Main Export Market(s) Asia, Australia, Central America, North America, South America, Eastern Europe, Western Europe, Middle East, Africa
Main Domestic Market All India
Certifications WHO GMP,GMP,GLP,ISO

Product Description

is one of the biggest manufacturer, supplier, exporter and trader ofthe LAFUTIDINEfinished formulations moreover LAFUTIDINE API. Niksan Pharmaceutical is the huge manufacturer, exporter andsupplier of LAFUTIDINE API and formulation situated in Ankleshwar, Gujarat, India.

NiksanPharmaceutical is the suppliers, manufacturer, exporters and trader of
LAFUTIDINE inthedomestic level as well as the international market.

Niksan is anIndian based pharmaceutical company so it also supplies and manufactures the LAFUTIDINE to allIndian states like Gujarat, Maharashtra, Punjab, Delhi, Tamilnadu, Goa, UttarPradesh, Karnataka, Jammu & Kashmir, West Bengal, Assam, Rajasthan,Hyderabad, Karnataka, Kerala, Madhya Pradesh, Manipur,Meghalaya, Mizoram, Nagaland, Orissa, Punjab and Haryana.

NiksanPharmaceutical and Niksan group companies are exporters, suppliers andmanufacturers of the API and also LAFUTIDINE formulations in many countries for many years. Niksanpharmaceutical currently exports LAFUTIDINE API and Formulation to countries like New Zealand, Jordan,Belgium, United Kingdom, Australia, Italy, Ireland, Hong Kong, Morocco,,Portugal, France, South Africa, Philippines, Malaysia, Singapore, Israel,Greece, Saudi Arabia, Egypt, Taiwan, Netherlands, South Korea, Switzerland,Algeria, Pakistan, Canada, Vietnam, United States, Germany, Brazil and manyother countries.

LAFUTIDINEis a histamineH-receptor antagonist used mainly for the treatment of gastric ulcers,gastroesophageal reflux disease (GERD), and other acid-related gastrointestinaldisorders. It reduces gastric acid secretion and promotes mucosal defense

SYNONYSMS:FRG-8813, (+)-Lafutidine

IUPAC NAME: 2-[[2-[(furanylmethyl)thio]ethyl]amino]-N-[4-(piperidin-1-ylmethyl)phenyl]acetamide

CAS NO:118288-08-7

FORMULA:C22H29N3O4S

MOLECULAR MASS: 431.55 g/mol

STORAGE CONDITIONS:Store Lafutidine in a tightly closedcontainer at room temperature (20C to 25C). Keep away from excessive heat,moisture, and direct light.

HOW TO USE:Typical adult dosefor peptic ulcer 10 mg twice daily or as directed by a physician. Dosage mayvary depending on the severity of the condition and patient profile.

HOW LAFUTIDINEWORKS:Lafutidinecompetitively inhibits histamine H receptors on gastric parietal cells,reducing both basal and stimulated gastric acid secretion. It also enhancesmucosal blood flow and stimulates mucus secretion, offering gastroprotectiveeffects.

PHARMACOKINETICSOF LAFUTIDINE:

Absorption:Rapidly absorbed after oral administration.

Metabolism: Extensivelymetabolized in the liver.

Elimination half-life: ~24 hours.

Excretion: Mainly through urine as metabolites.

SIDE EFFECTSOF LAFUTIDINE: The normal side effects caused by lafutidine are Headache, diarrhea,constipation, dry mouth, rash, dizziness, or nausea. Rarely: hypersensitivityreactions, liver enzyme elevation.

PRECAUTIONS: Use with caution inpatients with renal or hepatic impairment. Not recommended in pregnancy orlactation unless prescribed. Avoid exceeding recommended dose.

CDSCO APPROVAL:

Lafutidine Tablets-5mg/10mg 16.11.09

Lafutidine Tablets-5mg/10mg 19.01.10

FORMULATIONSAVAILABLE IN MARKET:

LAFUTIDINE 10 MG tablets

LAFUTIDINE + DOMPERIDONE tablets/capsules

Note: Productprotected by valid patents are not offered for sale in countries where suchpatents are still valid and its liability is at Buyers Risk

REFERENCES:

www.webmd.com

https://pubchem.ncbi.nlm.nih.gov

https://go.drugbank.com

https://cdscoonline.gov.in

https://www.wikipedia.org/

https://www.drugs.com

https://www.zaubacorp.com

https://www.practo.com/consult

Reliable Treatment for Acid-Related Disorders

Lafutidine plays a significant role in managing acid reflux and peptic ulcers by reducing gastric acid secretion. Its high purity and stability ensure dependable results for patients and pharmaceutical manufacturers alike, making it an essential medicine for gastrointestinal health.

Exceptional Quality and Safety Standards

Produced under stringent pharmaceutical protocols, Lafutidine surpasses medicine-grade purity requirements. With heavy metal content below 0.1%, a particle size D90 less than 10 microns, and low loss on drying, it meets international quality benchmarks and ensures safe use in medical formulations.

Versatile Pharmaceutical Intermediate

Lafutidines physical and chemical properties allow it to easily blend into a range of formulations. Freely soluble in key solvents and stable under room temperature conditions, it provides pharmaceutical manufacturers with flexibility during drug development and production.

FAQs of LAFUTIDINE:

Q: How is Lafutidine used in the treatment of gastroesophageal reflux disease and peptic ulcer disease?

A: Lafutidine works by inhibiting gastric acid secretion, thus providing effective relief from symptoms associated with GERD and peptic ulcers. It is an important active ingredient in medications prescribed for these conditions.

Q: What is the typical process for storing Lafutidine to preserve its shelf life?

A: Lafutidine should be stored at room temperature in a dry and well-ventilated area. When kept under these recommended conditions, its shelf life extends up to three years, maintaining stability and potency.

Q: Where can Lafutidine be sourced for pharmaceutical manufacturing?

A: Lafutidine is available globally through distributors, exporters, importers, manufacturers, suppliers, and traders, notably from India. Reliable suppliers ensure compliance with international pharmaceutical standards.

Q: What benefits does Lafutidine offer in pharmaceutical applications?

A: Its high purity (98.0%), precise particle size, low heavy metal content, and effective solubility make Lafutidine a preferred choice in pharmaceutical formulations, guaranteeing safety and efficacy.

Q: When should Lafutidine be incorporated into pharmaceutical formulations?

A: Lafutidine is incorporated during the development and manufacturing stages of medications intended for gastrointestinal health, particularly those targeting acid reflux and ulcer management.

Q: How does the physical form and appearance of Lafutidine affect pharmaceutical production?

A: As a yellowish-white powder with fine particle size (D90 less than 10 microns), Lafutidine mixes well with other ingredients, enabling uniform distribution and consistent quality in final products.

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Plot No. 4706/03, Gidc Estate, SF-12, Shrinathji Arcade, Near Meghmani Chowkadi,Ankleshwar - 393002, Gujarat, India
Phone :91--9537871777
Email : info@niksanpharmaceutical.com

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info@niksanpharmaceutical.com
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