DOXOFYLLINE .

Name: DOXOFYLLINE .
Brand: NIKSAN PHARMACEUTICAL
Price: 1900 INR
Availability: InStock

1900 INR/Kilograms

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Product Details:

Taste Other
Shelf Life 3 Years
Solubility poorly soluble in water but soluble in some organic solvents
Molecular Weight 266.25 g/mol Grams (g)
Molecular Formula C11H14N4O4
Loss on Drying not more than 0.5% w/w
Melting Point between 142.0 and 146.0 C
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DOXOFYLLINE . Price And Quantity

Minimum Order Quantity 10 Kilograms
Price 1900 INR/Kilograms

DOXOFYLLINE . Product Specifications

Physical Form Powder
Usage Doxofylline is one type of anti-asthmatic drug. Doxofylline is belongs to the Bronchodilator type of medicine. Mainly Doxofylline is widely used in a treatment of chronic obstructive pulmonary disease (COPD) and also used to treat asthma. Doxofylline is also called xanthenes derivative drug which is used in breathing problems. We can say that Doxofylline makes breathing easier. Doxofylline acts as a posphodiesterase inhibitor which can use in bronchospasm and other respiratory disorders.
Taste Other
Shelf Life 3 Years
Solubility poorly soluble in water but soluble in some organic solvents
Molecular Weight 266.25 g/mol Grams (g)
Appearance White to Off-White Solid
Molecular Formula C11H14N4O4
Type Other
Medicine Name DOXOFYLLINE
Melting Point between 142.0 and 146.0 C
Loss on Drying not more than 0.5% w/w
Ph Level pH 7.4
Heavy Metal (%) 0.002%
Particle Size 70.73nm
EINECS No 274-239-6
Structural Formula C11H14N4O4
Boiling point 505.2C
CAS No 69975-86-6
HS Code 29420090
Purity(%) 99 %
Smell Other
Chemical Name 7-(1,3-Dioxolan-2-ylmethyl)theophylline
Grade Medicine Grade
Storage Keep away from moisture

DOXOFYLLINE . Trade Information

FOB Port SAHAR AIR CARGO
Supply Ability 100 Kilograms Per Week
Delivery Time 1 Days
Sample Available Yes
Sample Policy Free samples are available
Packaging Details HDPE DRUM WITH TWO INNER LDPE LINER
Main Export Market(s) Asia, Australia, Central America, North America, South America, Eastern Europe, Western Europe, Middle East, Africa
Main Domestic Market All India
Certifications FDCA, GMP, GLP AND ISO

Product Description

Niksan Pharmaceutical is words top leading manufacturer, exporter,trader and supplier of Doxofylline APIas well as finished pharmaceutical products of Doxofylline among the pharmaceutical companies. Our productDoxofylline is widely used and appreciated by our group companies and also ourcustomers and users all around the nations. We offer the Doxofylline in veryaffordable price.

Niksan Pharmaceutical and Niksangroup companies are the very well-known manufacturers, suppliers anddistributors of Doxofylline products.

Niksan Pharmaceutical are manufacturing and exporting very largequantity of Doxofylline in countrieslike Philippines, Bangladesh, Nepal, Pakistan, Thailand, United states, Paraguay,Argentina, Dominican Republic, Sudan, Hong Kong, Seychelles, Algeria, Iran,Bulgaria, Lithuania, Poland, Sri Lanka, Romania, Uruguay, Serbia, New Zealand,Sweden, Hungary, Mauritius, Vanuatu, Malta, Kazakistan, Slovenia, Bolivia,Japan, Russia, Afghanistan, Latvia, Lithuania, United Arab Emirates,Seychelles, Peru, Switzerland, Tunisia, France, Chile, South Korea, United Kingdom,Australia, Greece, Austria and Germany.

Doxofylline is one type of anti-asthmatic drug. Doxofyllineis belongs to the Bronchodilator type of medicine. Mainly Doxofylline is widelyused in a treatment of chronic obstructive pulmonary disease (COPD) and also used to treatasthma.

Doxofylline is also called xanthenes derivative drugwhich is used in breathing problems. We can say that Doxofylline makesbreathing easier.

Doxofylline acts as a posphodiesterase inhibitorwhich can use in bronchospasm and other respiratory disorders.

SYNONYMS: Doxofilina,Doxofylline, Doxophylline.

IUPAC NAME: 7-[(1, 3-dioxolan-2-yl) methyl]-1, 3-dimethyl-2, 3, 6, 7-tetrahydro-1H-purine-2,6-Dione

CAS NO: 69975-86-6

FORMULA: C₁₁H₁₄N₄O₄

MOLECULAR MASS: 266.25 g/mol

STORAGE: Doxofylline is mainly comes in crystalline form sostore in a cool and dry place. Do not store in moistly or wet place likebathroom or kitchen. Keep the medicine away from reach of children and pets. Storethe medication as directed by your doctor.

APPLICATION OF DOXOFYLLINE: Doxofylline is anantitussive medicine which is mostly used in a treatment of asthma and otherrespiratory problems. Doxofylline shows fewer side effect then the otherxanthine type of medicine, thats why Doxofylline chosen over the otherxanthine class drug.

HOW TO USE: Doxofylline comes in two dosage forms oneis Tablet and Syrup. Simply take Doxofylline tablet or syrup by mouth (orally)with food or without food. The prescribed dose of Doxofylline must be1200mg perday. Try to take medicine at a same time every day for the better improvement.

HOW DOXOFYLLINE WORKS: The main mechanism of action ofDoxofylline is not well known but we can say that theDoxofylline works byinhibiting the posphodiesterase activity, by this process the cAMP level raisesand by this the smooth muscle relaxation occurs.

CONTRAINDICATIONS OF DOXOFYLLINE: If you havehypersensitivity kindly avoid Doxofylline and chose alternative medicine. Kindlyavoid the Doxofylline medication if you have any liver or kidney related problemsor if you have any hypoxemia (low O2 level in blood) or have any cardiacarrhythmias. Before the writing of prescription tell your doctor if you havehistory of peptic ulcer or hyperthyroidism.

PHARMACOKINETICS OF DOXOFYLLINE: Doxofylline workingvery differently in the body by that after taking of the regular doseDoxofylline reaches in steady state in about 4 days. The absolute bio availabilityof Doxofylline is 6325%. Basically methylxanthines are distributed into all over bodycompartment. The residues of Doxofylline are found in breast milk also.Doxofylline undergoes hepatic metabolism in which 90% of the drug clears fromthe body. Doxofylline is orally administered drug is only 4% excreted by theurination, the remaining drug will excreted in faces.

SIDE EFFECTS OF DOXOFYLLINE: There were very lessside effects of Doxofylline are noticed, most of them are very common sideeffects like nausea, vomiting, headache, obsess with food or anorexia. Thereare other side effects of Doxofylline like heart burn, dyspepsia are thenotable side effects.

PRECAUTIONS OF DOXOFYLLINE: Tell your doctor if you have any historyof peptic ulcer or hyperthyroidism. Kindly do not take Doxofylline if you haveany liver or kidney problem.

CDSCO APPROVAL: Doxofylline tablet (20mg and 400mg)tablets are approved by CDSCO in India in 31.08.2005.

Doxofylline syrup(20mg/ml) is approved by CDSCO in India in 31.08.2005.

Doxofylline Syrup (20mg/ml) is approved by CDSCO in India in30.03.2006.

Doxofylline Tablet (400mg) is approved by CDSCO in India in08.02.2006.

Doxofylline ER tablets (400mg/800mg) areapproved by CDSCO in India in 12.03.2008.

Doxofylline 400 mg + Ambroxol 30 mg Tablets are approved by CDSCOin India in 23.12.2009.

Doxofylline MR Tablet (650mg) is approved by CDSCO in India in11.03.2010.

FORMULATION OF DOXOFYLLINE AVAILABLEIN MARKET:

Doxofylline tablets20mg

Doxofylline tablets400 mg

Doxofylline syrup20mg/ml

Doxofylline ER tablets 400mg

Doxofylline ER tablets 800mg

Doxofylline 400 mg + Ambroxol 30 mg tablets

Doxofylline MR Tablets 650mg

Note: Product protected by valid patents are notoffered for sale in countries where such patents are still valid and itsliability is at Buyers Risk

REFERENCES:

www.webmd.com

https://pubchem.ncbi.nlm.nih.gov

https://go.drugbank.com

https://cdscoonline.gov.in

https://www.wikipedia.org/

https://www.drugs.com

https://www.zaubacorp.com

https://www.practo.com/consult

Broad-Spectrum Application and Benefits

Doxofylline serves as a reliable solution for patients suffering from asthma and chronic obstructive pulmonary disease (COPD), offering effective symptom relief. Its unique action as a phosphodiesterase inhibitor not only supports lung health but also makes breathing easier by minimizing airway resistance. The medicine is valued for its consistent efficacy and well-documented safety profile.

Proper Storage and Handling for Maximal Potency

Ensure Doxofylline is stored in a tightly closed container, away from moisture and heat. Place it in a cool, dry areapreferably not in the kitchen or bathroom. Maintaining these conditions preserves its effectiveness throughout its 3-year shelf life. Protecting it from damp or humid environments is crucial for long-term pharmaceutical stability.

Expert Manufacturing and Quality Assurance

Doxofylline is produced by Niksan Pharmaceutical, a trusted manufacturer adhering to strict GMP protocols. High-grade raw materials coupled with advanced manufacturing enable consistent quality with a purity of 99%. The product is available for pharmaceutical distributors, importers, and traders, ensuring traceable quality and ready supply globally.

FAQs of DOXOFYLLINE:

Q: How should Doxofylline be stored for optimal stability?

A: Doxofylline should be stored in a well-closed container in a cool, dry location. Avoid keeping it in moist spaces like bathrooms or kitchens to maintain its integrity and effectiveness. Suitable storage helps prevent degradation over its 3-year shelf life.

Q: What is the recommended dosage and form for Doxofylline administration?

A: The advised form of Doxofylline is typically tablets or capsules, with a total daily dose of approximately 1200mg. This can be taken orally, with or without food, based on the physicians directions.

Q: When is Doxofylline recommended for use?

A: Doxofylline is recommended for individuals diagnosed with asthma or chronic obstructive pulmonary disease (COPD). It is particularly effective in providing relief from symptoms such as bronchospasm and breathing difficulties.

Q: Where can Doxofylline be sourced in bulk for pharmaceutical purposes?

A: Doxofylline can be obtained from reputable manufacturers like Niksan Pharmaceutical, which offers the product in medicine-grade quality, supported by GMP certifications and a ready DMF for global supply needs.

Q: How does Doxofylline benefit individuals with respiratory disorders?

A: Doxofylline eases airway resistance and controls bronchospasms, leading to improved breathing. Its function as a bronchodilator makes it an essential medication for managing persistent respiratory ailments.

Q: What is the process for taking Doxofylline tablets or syrup?

A: Doxofylline should be taken by mouth, either with food or on an empty stomach, preferably at evenly spaced intervals throughout the day as advised by your healthcare provider.

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