DESLORATADINE

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Product Details:

Loss on Drying often around 0.1%
Taste Other
Particle Size 1-5 m
Shelf Life 3 Years
Melting Point 150C to 159C
Smell Other
EINECS No 100643-71-8
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DESLORATADINE Price And Quantity

Minimum Order Quantity 5 Kilograms

DESLORATADINE Product Specifications

Molecular Formula C19H19ClN2
Heavy Metal (%) NMT 20ppm
Storage Room Temperature
Solubility soluble in ethanol (95%), slightly to very slightly soluble in heptane, and very slightly soluble to practically insoluble in water
HS Code 29420090
Structural Formula C19H19ClN2
CAS No 100643-71-8
Appearance White to Off-White Solid
Purity(%) 99 %
Molecular Weight 310.82 g/mol Grams (g)
Ph Level 4.7 to 5.53
Loss on Drying often around 0.1%
Physical Form Powder
Chemical Name 8-chloro-6,11-dihydro-11-(4-piperidinylidene)-5H-benzocyclohepta[1,2-b]pyridine
Usage Desloratadine is one type of antihistamine. It is used to relieve the symptoms of hay fever and hives of the skin. Antihistamines work by preventing the effects of a substance called histamine, which is produced by the body. Histamine can cause itching, sneezing, runny nose, and watery eyes.
Particle Size 1-5 m
Taste Other
Medicine Name DESLORATADINE
Type Other
Grade Medicine Grade
Smell Other
EINECS No 100643-71-8
Melting Point 150C to 159C
Shelf Life 3 Years
Boiling point 467.9 C

DESLORATADINE Trade Information

FOB Port INDIA
Payment Terms Cash Advance (CA), Cheque
Supply Ability 100 Kilograms Per Month
Delivery Time 1 Days
Sample Available No
Packaging Details HDPE DRUM WITH TWO INNER LDPE LINNER
Main Export Market(s) Asia, Australia, Central America, North America, South America, Eastern Europe, Western Europe, Middle East, Africa
Main Domestic Market All India, South India, Central India, West India, North India, East India, Gujarat, Karnataka, Kerala, Lakshadweep, Mizoram, Meghalaya, Manipur, Andhra Pradesh, Bihar, Chandigarh, Daman and Diu, Goa, Jharkhand, Odisha, Punjab, Assam, Delhi, Dadra and Nagar Haveli, Andaman and Nicobar Islands, Arunachal Pradesh, Chhattisgarh, Haryana, Himachal Pradesh, Jammu and Kashmir, Madhya Pradesh, Maharashtra, Nagaland, Rajasthan, Sikkim, Tamil Nadu, Telangana, Tripura, Pondicherry, Uttar Pradesh, Uttarakhand, West Bengal
Certifications GMP, FDCA

Product Description

is leading manufacturer and distributer ofthe Desloratadine among the other countries. NiksanPharmaceutical is one of the major the supplier, distributer, exporter andmanufacturer of the Desloratadine API and finished formulations in Ankleshwar,Gujarat, India. The products of Niksan Pharmaceutical and Niksan groupcompanies are widely appreciated by the clients and other companies.

Niksan Pharmaceutical is the supplier, manufacturer, exporter andtrader of Desloratadine in the domestic level as well as theinternational market.

Niksan Pharmaceutical provides Desloratadine API in all over Indian states like Jammu& Kashmir, Himachal Pradesh, Uttarakhand, Punjab, Kerala, Chandigarh,Chhattisgarh, Andhra Pradesh, Rajasthan, Meghalaya, Mizoram, Nagaland, Orissa,,Dadraand Nagar Haveli, Goa, Gujarat, Jharkhand,West Bengal, Karnataka, Kerala, Madhya Pradesh etc.

Niksan Pharmaceuticalalso provides Desloratadine API and finished formulations in all other countries of the world likeGermany, Switzerland, Poland, Latvia, Egypt, Lithuania, Estonia, Ukraine,Moldova, Russia, United States, Austria, Belarus, Serbia, India, Spain,Slovenia, Nigeria, Croatia, South Africa, Kazakhstan, Italy, Romania, Bulgaria,Portugal, South Korea, Greece, Philippines, Belgium, Saudi Arabia, Turkey,Japan etc.

Desloratadine isone type of antihistamine. It is used to relieve the symptoms of hay fever andhives of the skin. Antihistamines work by preventing the effects of a substancecalled histamine, which is produced by the body. Histamine can cause itching,sneezing, runny nose, and watery eyes.

SYNONYMS: Descarboethoxyloratadine, Desloratadina, Desloratadine

IUPAC NAME:13-chloro-2-(piperidin-4-ylidene)-4-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8),4,6,12,14-hexaene

CAS NO: 100643-71-8

FORMULA: C₁₉H₁₉ClN₂

MOLECULAR MASS:310.82 g/mol

STORAGE OF DESLORATADINE:

Blisters: This medicinalproduct doesnot require any special storage conditions.

APPLICATIONS OF DESLORATADINE:Desloratadine is used in adults and children to relieve hayfever and allergy symptoms, including sneezing; runny nose; and red, itchy,tearing eyes. It is also used to relievesymptoms of urticaria (hives; red, itchy raised areas of the skin), includingitching and rash.

HOW TO USE: Desloratadinecomes as a tablet, oral solution (liquid), and an orally disintegrating tabletto take by mouth. It is usually taken once a day with or without food. Follow the directions on your prescription labelcarefully, and ask your doctor or pharmacist to explain any part you do notunderstand.

HOW DESLORATADINE WORKS: Desloratadine is anantihistamine. It is used to relieve the symptoms of hay fever and hives of theskin. Antihistamines work bypreventing the effects of a substance called histamine, which is produced bythe body.Histamine can cause itching, sneezing, runny nose, and watery eyes.

CONTRAINDICATIONS OF DESLORATADINE: Desloratadineproducts are contraindicated in patients who are hypersensitive to Desloratadineor to any of the product ingredients or to loratadine. The anticholinergic activity of H1-antagonists may result in thickenedbronchial secretions in the respiratory tract thereby aggravating asthma or anasthmatic attack.

PHARMACOKINETICS OF DESLORATADINE:Desloratadine is well absorbed from the gut and reaches highest blood plasma concentrationsafter about three hours. In the bloodstream, 83to 87% of the substance are bound to plasma proteins. Desloratadine ismetabolized to 3-hydroxydesloratadine in a three-step sequence in normalmetabolizers.

SIDEEFFECTS OF DESLORATADINE: If youre allergic to it or any of itscomponents. This drug can cause ahypersensitivity (allergic) reaction. This can lead to itching, rash, swelling,headache, nausea, diarrhea, dizziness, sore throat,shortness of breath, andswelling of your lips, face, or tongue.

PRECAUTIONS:Thepresence of other medical problems may affect the use of this medicine. Make sure you tellyour doctor if you have any other medical problems, especially: Liver disease or. Kidney diseaseEffects ofdesloratadine may be increased because of slower removal from the body.

CDSCOAPPROVAL:

Desloratadine bulk & tablets are approved by CDSCO in Indiain 30-10-2001

FORMULATIONAVAILABLE IN MARKET:

Desloratadine5 MG Tablets

Desloratadine And Montelukast Tablets

Desloratadine + Pseudoephedrine

Ambroxol HCl 75 MG (S.R) +Desloratadine 5 MG Capsule

Desloratadine(2.5MG)+Ambroxol(30MG)+Guiphenasine(50MG)+Menthol(1MG/5Ml)Syrup

Note: Product protected by valid patents are not offered for sale incountries where such patents are still valid and its liability is at BuyersRisk

REFERENCES:

www.webmd.com

https://pubchem.ncbi.nlm.nih.gov

https://go.drugbank.com

https://cdscoonline.gov.in

https://www.wikipedia.org/

https://www.drugs.com

https://www.zaubacorp.com

https://www.practo.com/consult

Effective Allergy Relief

Desloratadine functions as a second-generation antihistamine, providing reliable relief from hay fever symptoms and chronic urticaria. By inhibiting histamine, it minimizes discomfort such as sneezing, itchy skin, runny nose, and watery eyes, making it a preferred choice among allergy medications.

Stable and High-Quality Formulation

Manufactured under stringent pharmaceutical standards, Desloratadine offers excellent purity and chemical stability. Its solid, powdery form is easy to handle and is stable at room temperature, with a low moisture content and minimal heavy metal presence, ensuring consistent therapeutic performance throughout its shelf life.

FAQs of DESLORATADINE:

Q: How should Desloratadine be stored to maintain its effectiveness?

A: Desloratadine should be stored at room temperature in a dry environment. Keeping it away from moisture and direct sunlight will help preserve its stability and ensure the medication retains its full efficacy for up to 3 years.

Q: What is the primary benefit of using Desloratadine?

A: The main benefit of Desloratadine is its ability to relieve symptoms associated with hay fever and skin hives, including sneezing, runny nose, itchy or watery eyes, and irritated skin, by blocking the action of histamine in the body.

Q: When is Desloratadine typically administered?

A: Desloratadine is usually taken when allergic symptoms first appear or as directed by a healthcare provider. It can be used daily during periods of high pollen or allergen exposure to manage ongoing symptoms.

Q: Where can Desloratadine be sourced in India?

A: Desloratadine is available through reputable distributors, exporters, importers, manufacturers, suppliers, and traders throughout India. Always ensure you purchase from certified pharmaceutical suppliers to guarantee product quality and authenticity.

Q: What is the process of manufacturing Desloratadine?

A: Desloratadine is manufactured under strict pharmaceutical guidelines to achieve high purity (99%) and proper particle size (15 m). Quality control measures ensure the heavy metal content stays below 20 ppm, and the compound appears as a white to off-white solid.

Q: How is Desloratadine used in medical treatments?

A: Desloratadine is primarily used as an oral medication to counteract the effects of histamine during allergic reactions. It helps manage hay fever, seasonal allergies, and chronic urticaria, providing targeted relief to affected individuals.

Q: What are the solubility properties of Desloratadine and how do they affect its use?

A: Desloratadine is soluble in ethanol (95%), slightly to very slightly soluble in heptane, and very slightly soluble to practically insoluble in water. These properties make it well-suited for formulation into oral dosage forms and enhance its pharmacological stability.

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Phone :91--9537871777
Email : info@niksanpharmaceutical.com

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Mobile :+919537871777
info@niksanpharmaceutical.com
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