Thiocolchicoside Thiocolchicoside Thiocolchicoside Thiocolchicoside Thiocolchicoside Thiocolchicoside Thiocolchicoside Thiocolchicoside Thiocolchicoside Thiocolchicoside Thiocolchicoside
Thiocolchicoside
Thiocolchicoside Thiocolchicoside Thiocolchicoside Thiocolchicoside Thiocolchicoside Thiocolchicoside Thiocolchicoside Thiocolchicoside Thiocolchicoside Thiocolchicoside

Thiocolchicoside

450000 INR/Gram

Product Details:

  • Drug Type Medicine Raw Materials
  • Product Type Medicine Raw Materials
  • Form Powder
  • Ingredients ACTIVE PHARMACEUTICAL INGREDIEANT
  • Physical Form Powder
  • Function Increase Immunity
  • Treatments & Functions Other
  • Supply Ability : Per Month
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Price And Quantity

  • 450000 INR/Gram
  • 100 Kilograms

Product Specifications

  • Medicine Raw Materials
  • Store it at room temperature (25 to 30°C), and in an airtight container.
  • 4 MG
  • TABLETS AND CAPSULES
  • Medicine Raw Materials
  • ACTIVE PHARMACEUTICAL INGREDIEANT
  • Other
  • 100 KG Unit
  • Powder
  • TABLETS AND CAPSULES
  • Increase Immunity
  • Powder
  • Aged Person, Adults

Trade Information

  • SAHAR AIR CARGO
  • Paypal, Western Union, Telegraphic Transfer (T/T), Letter of Credit at Sight (Sight L/C), Letter of Credit (L/C), Delivery Point (DP), Days after Acceptance (DA), Cheque, Cash in Advance (CID), Cash Advance (CA), Cash on Delivery (COD), Cash Against Delivery (CAD)
  • Per Month
  • 7 Days
  • Yes
  • Free samples are available
  • Double LDPE Liners in HDPE carboys
  • Africa, Middle East, Western Europe, Eastern Europe, South America, North America, Central America, Australia, Asia
  • West Bengal, Uttarakhand, Uttar Pradesh, Tripura, Telangana, Tamil Nadu, Sikkim, Rajasthan, Pondicherry, Punjab, Odisha, Nagaland, Manipur, Meghalaya, Mizoram, Maharashtra, Madhya Pradesh, Lakshadweep, Kerala, Karnataka, Jharkhand, Jammu and Kashmir, Himachal Pradesh, Haryana, Goa, Gujarat, Daman and Diu, Dadra and Nagar Haveli, Delhi, Chandigarh, Chhattisgarh, Bihar, Arunachal Pradesh, Assam, Andhra Pradesh, Andaman and Nicobar Islands, West India, East India, North India, Central India, South India, All India
  • FDCA, GMP, GLP AND ISO

Product Description

Niksan Pharmaceutical   is one of the top manufacturer, distributor,exporter, and trader of Thiocolchicoside in the India and also in the world otherCountries. Generally Thiocolchicoside is the main product of NiksanPharmaceutical which distributing as a form of API and finished formulations.The product of Niksan Pharmaceutical and Niksan group is widely acceptable byour customer.

 

Niksan Pharmaceuticals  group company Niksan Healthcare  is also a manufacturers and supplier of the Thiocolchicoside in all dosage form.

 

Niksan Pharmaceutical provides Thiocolchicoside API in all over Indianstates like Goa,Gujarat, Jammu and Kashmir, Jharkhand, West Bengal, Karnataka, Kerala, MadhyaPradesh, Maharashtra, Manipur, Meghalaya, Mizoram, Nagaland, Orissa, Punjab,Rajasthan, Sikkim, Tamil Nadu, Tripura and many other states.

 

Niksan Pharmaceutical ismanufacturing and exporting Thiocolchicoside from last many years in countrylike Reunion, France, Libya, Pakistan, Morocco, Tunisia, Kenya, Algeria,Greece, Vietnam, Ecuador, UAE, Turkey, Italy, UK, Germany, USA, Argentina,Armenia, Australia, Botswana, Brazil, Brunei, Colombia, Comoros, Congo FreeState, Georgia, Germany, Ghana, Jamaica, Japan, Jordan etc.

 

Thiocolchicoside is ananti-inflammatory drug which is used as muscle relaxant for treatment of painful muscular conditions.

Thiocolchicosideacts asa competitive GABA receptor antagonist andalso glycine receptor antagonist which is use as a pain killer.

 

SYNONYMS:TCC, Thiocolchicine 2-glucoside analog

 

IUPAC NAME: N-[(10S)-3,4-dimethoxy-14-(methylsulfanyl)-13-oxo-5-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}tricyclehexadeca-1(16),2,4,6,11,14-hexaen-10-yl]acetamide

 

CAS NO: 602-41-5

 

FORMULA: C27H33NO10S

                                                                                                                                                                                                                       

MOLECULAR MASS: 563.62 g/mol

 

STORAGE OF THIOCOLCHICOSIDE: Store it atroom temperature (25 to 30°C), and in an airtight container. Keep medicine awayfrom the reach of children and pets.

 

APPLICATIONS OF THIOCOLCHICOSIDE:Thiocolchicoside is used to treatment of Muscle spasm. Thiocolchicoside act asan anti-inflammatory drug which is used as muscle relaxant for treatment of painful muscular conditions. Thiocolchicosideworks as a competitive GABA receptor antagonist andalso glycine receptor antagonist which is use as a pain killer.

 

HOW TO USE: Thiocolchicosideis available in tablet form so you can take this medicine by mouth. You cantake Thiocolchicoside medicine every 12 hours up to 5 days.   

 

HOWTHIOCOLCHICOSIDE WORKS: Thiocolchicosideact as a muscle relaxant by activating GABA inhibitory pathways. Thiocolchicosideis an anti-inflammatory drug which is used as muscle relaxant in the treatment of painful muscular conditions.

 

CONTRAINDICATIONOFTHIOCOLCHICOSIDE: If you havehypersensitivity to Thiocolchicoside kindly avoid this medicine. Kindly avoidthis medicine during pregnancy and lactation.

 

PHARMACOKINETICS OFTHIOCOLCHICOSIDE:Thiocolchicoside absorption is rapidly after oraladministration. Half-life of Thiocolchicoside is approximately 5 to 6 hours. AveragePeak Plasma Concentration of Thiocolchicoside is 49 mg/ml. Thiocolchicoside ismainly excreted by feces (79%) and 20% excreted by urine.

 

SIDE EFFECTS OF THIOCOLCHICOSIDE: The most common side effect of Thiocolchicoside is allergyand vasovagal reactions. Other side effects are liver injury, pancreatitis,seizures, blood cell disorders, yellowing of skin and eyes, Photosensitivity, Dry mouth, Headache etc.

Thiocolchicoside can often cause skin disorders like rhabdomyolysis, and reproductive disorders. In experimental animals,Thiocolchicoside is teratogenic. Sometimes Thiocolchicoside damageschromosomes.

 

PRECAUTIONS:If you see any signs of liver toxicity like Abdominal pain inthe upper right portion of the abdomen, Fatigue, Loss of appetite, Nausea andvomiting stop to taking Thiocolchicoside. If you have a diarrhoea during the administration of this drug kindlyavoid medicine. Take this medicine during pregnancy and breastfeeding only ifit is clearly needed.

 

CDSCOAPPROVAL:

Diclofenac Sodium IP (as sustained release Pellets)100mg + Thiocolchicoside (as sustained release pellets) 16mg Capsule. (NewDosage Form) is approved by CDSCO in India in 15.11.2011

DexketoprofenTrometamol 25mg + Thiocolchicoside 4mg tablets are approved by CDSCO in India in 20.05.2010

Thiocolchicoside 8 mg + Etoricoxib 60 mg tablets are approvedby CDSCO in India in 25.04.2009

Thiocolchicoside 4mg/8mg + Ketoprofen 50mg/100mgtablets are approved by CDSCO in India in 11.06.2008

Thiocolchicoside injection are approved by CDSCO inIndia in 25.03.2004

Aceclofenac (100mg) + Thiocolchicoside (8 mg) tabletsare approved by CDSCO in 03.08.2009

Aceclofenac (100mg) + Thiocolchicoside (4 mg) tablets(Additional strength) are approved by CDSCO in 11.08.2009

Etodolac 300/300mg +Thiocolchicoside 4/8mg are approvedby CDSCO in 19.07.2010

Etodolac 400mg/400mg + Thiocolchicoside 4mg/8mg tabletare approved by CDSCO in 09.09.2010

Each sustained release tablet contains:Thiocolchicoside IP 8/16mg + Lornoxicam 8/16mg (Additional Strength) are approvedby CDSCO in 08.04.2013

Thiocolchicoside 0.25% + Methyl salicylate IP 100mg +Menthol IP 50mg + Absolute alcohol IP 50mg per gm gel are approved by CDSCO in 11.10.2010

Diclofenac + Thiocolchicoside (50mg (EC) + 8mg)Capsules are approved by CDSCO in 21.10.2008

Aceclofenac IP (Sustained released pellets) 200mg/200mg+ Thiocolchicoside IP (Sustained released pellets) 8mg/16mg Capsules. (NewDosage Form) are approved by CDSCO in 04.01.2012

Thiocolchicoside + Etoricoxib (4mg + 60 mg) FC Tabletsare approved by CDSCO in 17.11.2008

Diclofenac + Thiocolchicoside (50 mg + 4 mg) Capsulesare approved by CDSCO in 24.12.2008

S (+) Etodolac 300mg + Thiocolchicoside 8mg Tablet are approvedby CDSCO in 05.01.2011

Lornoxicam4mg/4mg + Thiocolchicoside 4mg/8mg tablets are approved by CDSCO in 12.02.2010

Thiocolchicosidetablets are approved by CDSCO in 25.03.1996

Lornoxicam8mg/8mg + Thiocolchicoside 4mg/8mg Tablets are approved by CDSCO in 23.03.2010

 

FORMULATION AVAILABLE IN MARKET:

Diclofenac Sodium IP (as sustained release Pellets)100mg + Thiocolchicoside (as sustained release pellets) 16mg Capsules (NewDosage Form)

DexketoprofenTrometamol 25mg + Thiocolchicoside 4mg tablets

Thiocolchicoside 8 mg + Etoricoxib 60 mg tablets Thiocolchicoside4mg/8mg + Ketoprofen 50mg/100mg tablets

Thiocolchicoside injection s

Thiocolchicoside 0.25% + Methyl salicylate IP 100mg +Menthol IP 50mg + Absolute alcohol IP 50mg per gm gel

Diclofenac + Thiocolchicoside (50mg (EC) + 8mg)Capsules Aceclofenac IP (Sustained released pellets) 200mg/200mg +Thiocolchicoside IP (Sustained released pellets) 8mg/16mg Capsules. (New DosageForm)

Thiocolchicoside + Etoricoxib (4mg + 60 mg) FC Tablets

Diclofenac + Thiocolchicoside (50 mg + 4 mg) Capsules

S (+) Etodolac 300mg + Thiocolchicoside 8mg Tablets

Lornoxicam4mg/4mg + Thiocolchicoside 4mg/8mg tablets

Thiocolchicosidetablets

Lornoxicam8mg/8mg + Thiocolchicoside 4mg/8mg Tablets

Aceclofenac (100mg) + Thiocolchicoside (8 mg) tablets

Aceclofenac (100mg) + Thiocolchicoside (4 mg) tablets(Additional strength)

Etodolac 300/300mg +Thiocolchicoside 4/8mg tablets

Etodolac 400mg/400mg + Thiocolchicoside 4mg/8mg tablets

Each sustained release tablet contains:Thiocolchicoside IP 8/16mg + Lornoxicam 8/16mg (Additional Strength)

 

Note: Product protected by validpatents are not offered for sale in countries where such patents are stillvalid and its liability is at Buyers Risk.

 

REFERENCES:

 

www.webmd.com

https://pubchem.ncbi.nlm.nih.gov

https://go.drugbank.com

https://cdscoonline.gov.in

https://www.wikipedia.org/

https://www.drugs.com

https://www.zaubacorp.com

https://www.practo.com/consult

 

 

 

 

 

 


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