ONDANSETRON

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Product Details:

Smell Other
EINECS No 103639-04-9
Particle Size at least 80% are below 250 m
Storage Room Temperature
HS Code 29420090
Heavy Metal (%) NA
Molecular Formula C18H19N3O
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ONDANSETRON Price And Quantity

Minimum Order Quantity 5 Kilograms

ONDANSETRON Product Specifications

Type Pharmaceutical Intermediates
Chemical Name 1,2,3,9-Tetrahydro-9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-4H-carbazol-4-one
Molecular Formula C18H19N3O
Melting Point 175.0 to 180.0 C
Ph Level 3.5 to 5.5
Grade Other
CAS No 99614-02-5
Solubility under the acidic conditions is water-soluble
Taste Other
Structural Formula C18H19N3O
Appearance White to Off-White Solid
Loss on Drying between 1-5%
Boiling point 267-268 C
Molecular Weight 293.4 g/mol Grams (g)
Usage Ondansetron used as anti-emetic agent. Ondansetron blocks the action of 5-HT3 receptor which causes the nausea and vomiting symptoms.
Shelf Life 3 Years
Particle Size at least 80% are below 250 m
EINECS No 103639-04-9
Smell Other
Purity(%) 99 %
Medicine Name ONDANSETRON
Storage Room Temperature
Physical Form Powder
HS Code 29420090
Heavy Metal (%) NA

ONDANSETRON Trade Information

FOB Port NHAVA SHEVA
Supply Ability 100 Kilograms Per Week
Delivery Time 1 Days
Sample Available Yes
Sample Policy Free samples are available
Packaging Details HDPE DRUM WITH TWO LDPE INNER LINER
Main Domestic Market All India
Certifications WHO GMP,GMP,GLP,ISO

Product Description

is one of the leading manufacturer, supplier and exporter of the Ondansetron. The best product manufactured by NiksanPharmaceutical is Ondansetron. We manufacture, supply andexport best quality product of OndansetronAPI along with Ondansetronformulations.

NiksanPharmaceutical is the largest manufacturer, trader and supply of Ondansetron in all-over Ankleshwar,Gujarat, India.

NiksanPharmaceutical manufacture and supply the Ondansetronproduct to the Indian states like Maharashtra, Goa,Sikkim, Madhya Pradesh, Uttar Pradesh, Assam, Haryana, Delhi, Bihar, Meghalaya,Tamilnadu, Kerala, Gujarat, Rajasthan, Rajasthan, Punjab,Karnataka, and otherstates.

is manufacturer , supplier and exporter of Ondansetronin many countries from many years like New Zealand, United States,Paraguay, Indonesia, Mexico, Australia, Chile, Nepal, Venezuela, Ecuador,Puerto Rico, Colombia, Uruguay, Kenya, Bolivia, Canada, Peru, Bangladesh,Portugal, Ireland, United Kingdom, Iraq, United Arab Emirates, Singapore,Sweden, Iran, Pakistan, Spain, Argentina, Philippines, Saudi Arabia, Finland,Denmark, Switzerland, Netherlands, Germany, South Africa, Thailand, Egypt,Austria, Malaysia, Italy, Belgium, France, Poland, Vietnam, Turkey, Brazil andmany more countries.

Ondansetron belongs to5-HT3 antagonist class of medicine. Ondansetron used as an anti-emetic agent toprevent nausea and vomiting caused by the cancer therapy. It is also used toprevent vomiting caused by motion sickness.

IUPAC NAME: 9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-2, 3, 4, 9-tetrahydro-1H-carbazol-4-one

CAS NO: 99614-02-5

FORMULA: C₁₈H₁₉N₃O

MOLECULAR MASS: 293.4 g/mol

STORAGECONDITIONS: Store in cool and dry place, away from heat and light. Do not put inbathroom or ant misty place. Keep away from children.

HOW TO USE: This medication come inmouth dissolving formulation, so do not chew or break the medicine. Placemedicine on the tip of the tongue and allow dissolving it. Swallow the medicineafter dissolves in the mouth.

HOW ONDANSETRONWORKS: Ondansetronused as anti-emetic agent. Ondansetron blocks the action of 5-HT3 receptorwhich causes the nausea and vomiting symptoms.

PHARMACOKINETICS: Ondansetron absorbed in GI after the oral administration.Almost 73% drug binds with the plasma protein. The half life of Ondansetron is3-4 hours. Ondansetron eliminated from body by urination and feces.

SIDE EFFECTS: Side effects cause by Ondansetron isdizziness, light headedness, drowsiness, headache, tiredness. Other side effects like chest pain, irregularheartbeats, fainting, and abdominal pain. Muscle pain seen in the patients.

PRECAUTIONS: Before taking themedication tell your doctor if you are allergic towards the medicine. The medicinemakes you dizzy so kindly avoid drinking alcohol and cannabis. This drug makesyou dizzy so kindly avoid driving or operating machineries.

CDSCO APPROVAL: R-Ondansetron (As HCl. Dihydrate) (1mg/ml)injection approved by CDSCO in India in 12.01.2007,

Ondansetron Fast Dissolving Strips 4mg/8mg (New dosage form) approvedby CDSCO in India in22.11.2011

Ondansetron orally disintegrating tablet (4mg/8mg) (additionaldosage form)approved by CDSCO in India in 10.10.2007

Ondansetron tablet and injection approved by CDSCO in India in12.02.1994

Ondansetron Rapid Film Oral Strip 4/8 mg approved by CDSCO inIndia in16.11.2010

Ondansetron Hydrochloride Mouth Melting Strips 4mg approved byCDSCO in India in29.03.2012

R (+) Ondansetron (2mg/4mg) tablet approved by CDSCO in India in15.04.2005

Ondansetron Hydrochloride Oral Spray 2mg (Each spray deliversondansetron-2mg)approved by CDSCO in India in 08.11.2012

R (-) Ondansetron oral Solution (1mg/5ml) approved by CDSCO inIndia in27.05.2005

FORMULATIONS AVAILABLE IN MARKET:

Ondansetron Fast Dissolving Strips 4mg

Ondansetron Fast Dissolving Strips 8mg

Ondansetron 4mg orally disintegrating tablets

Ondansetron 8mgorally disintegrating tablets

Ondansetron injections

Ondansetron Rapid Film Oral Strips 4mg

Ondansetron Rapid Film Oral Strips 8mg

R (+) Ondansetron 2mg tablets

R (+) Ondansetron 4mg tablets

R (-) Ondansetron 1mg/5ml oral Solution

Note: Product protected by valid patents are notoffered for sale in countries where such patents are still valid and itsliability is at Buyers Risk.

REFERENCES:

www.webmd.com

https://pubchem.ncbi.nlm.nih.gov

https://go.drugbank.com

https://cdscoonline.gov.in

https://www.wikipedia.org/

https://www.drugs.com

https://www.zaubacorp.com

https://www.practo.com/consult

How Ondansetron Works

Ondansetron functions as a 5-HT3 receptor antagonist, interrupting the signals that trigger nausea and vomiting. By acting on these receptors, particularly in the gastrointestinal tract and brain, it is highly effective for patients undergoing cancer therapy or surgery.

Dosage and Administration Guidance

The mouth dissolving formulation should not be chewed or broken. Instead, place the tablet on your tongue and allow it to dissolve completely before swallowing. Always follow your healthcare providers instructions for dosage, and do not exceed recommended amounts.

Key Storage Instructions

For optimal stability and effectiveness, store Ondansetron in a cool, dry environment, shielded from direct sunlight and heat. Ensure the container is tightly closed to preserve the products integrity over its 3-year shelf life.

FAQs of ONDANSETRON:

Q: How should I take Ondansetron mouth dissolving tablets?

A: To use the mouth dissolving tablet, place it on the tip of your tongue and allow it to dissolve fully. Do not chew or break the tablet. Swallow after it completely dissolves in your mouth.

Q: What is Ondansetron commonly used for?

A: Ondansetron is primarily used to prevent and manage nausea and vomiting caused by cancer chemotherapy, radiation therapy, or surgical procedures.

Q: When should Ondansetron be administered for best results?

A: Following your doctors instructions is essential. Typically, Ondansetron should be given before the start of chemotherapy, radiation, or surgery, and may be continued as recommended to prevent or manage symptoms.

Q: Where should Ondansetron powder be stored to maintain its quality?

A: The powder should be stored at room temperature in a cool, dry place, away from direct sunlight and heat. Always keep the container tightly sealed.

Q: What are the benefits of using Ondansetron?

A: Ondansetron provides effective relief from nausea and vomiting, improving comfort and quality of life for individuals undergoing treatments known to cause these side effects.

Q: Is Ondansetron available in forms other than tablets?

A: Yes, Ondansetron is also available in injectable and oral solution forms, allowing flexibility in administration based on patient needs.

Q: Can Ondansetron be used for other gastric issues?

A: While primarily indicated for nausea and vomiting from chemotherapy, radiation, or surgery, Ondansetron may sometimes be used as prescribed by a healthcare professional for similar gastric complaints.

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Phone :91--9537871777
Email : info@niksanpharmaceutical.com

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