Niksan Pharmaceutical is words top leading manufacturer, exporter, trader and supplier of DrotaverineAPI as well as finished pharmaceutical products of Drotaverineamong the pharmaceutical companies. Our product Drotaverineis widely used and appreciated by our group companies and also ourcustomers and users all around the nations. We offer the Drotaverinein very affordable price.
Niksan Pharmaceutical provides API and finishedformulations of Drotaverine in allover Indian states Like Kerala, Gujarat, Haryana, Rajasthan, Madhya Pradesh,Uttar Pradesh, Rajasthan, Karnataka, Meghalaya, Tamilnadu, Goa, Sikkim, Assam,Punjab, Delhi, Bihar, Jammu Kashmir Etc.
Niksan Pharmaceutical is also large exporter ofthe API and finished pharmaceutical products of Drotaverine in many countries for years. The countries where weexporting are Myanmar (Burma), Nepal, Afghanistan, Uganda, Ghana, Yemen,Pakistan, Syria, Lithuania, Vietnam, Iraq, Nigeria, Thailand, Malaysia,Hungary, Romania, Egypt, Bolivia, Ukraine, Poland, United Kingdom, MexicoRussia, Germany, Canada, Turkey, United States, Spain, France and many morecountries.
Drotaverine is one type ofanti-spasmodic drug. Drotaverine is the posphodiesterase 4 inhibitor.
Drotaverine used toenhance the cervical dilation during the birth process. Drotaverine also treatthe spasm and twitches the smooth muscle of the stomach.
SYNONYMS OF DROTAVERINE: Drotaverin, Drotaverina,Drotaverine, Drotaverinum.
IUPAC NAME: (1Z)-1-[(3, 4-diethoxyphenyl)methylidene]-6, 7-diethoxy-1, 2, 3, 4-tetrahydroisoquinoline.
MOLECULAR MASS: 397.50 g/mol
STORAGE CONDITIONS: Store in room temperature in dryplace. Do not put it in bathroom or fridge. Keep away from direct light andheat. Keep away from children and pet.
HOW TO USE: Take the medicine orally with orwithout food. If you have any confusion regarding to the medication ask yourdoctor. Take medication regularly to achieve maximum benefits from it.
HOW DROTAVERINEWORKS: Drotaverine is anti-spasmodic drug which inhibits the phosphodiesterase4 enzyme and by this it cause vasodilation of the cervical muscle whiles thebirth process. It is also used in the treatment of headache and syndrome.
PHARMACOKINETICS: Drotaverineinhibits the phosphodiesterase 4 enzyme and increase the cAMP concentration. Thebioavaibility of Drotaverine is variable. About 80-95% the Drotaverine drugbinds with the plasma protein. The half-life of Drotaverine is between 7-12hrs.The elimination of the Drotaverine is done mainly by the bile.
SIDE EFFECTS: The sideeffects of Drotaverine are nausea, vomiting, swelling of face, lips, tongue. Drotaverinealso cause dry mouth, change in pulse rate, Dizziness, headache.
PRECAUTIONS: Tell yourdoctor if you have allergic reaction from the Drotaverine. If you have pastdisease like liver disease, kidney problem or heart related problem kindlyconsult and tell your doctor. Do not take alcohol or marijuana while taking themedication. Do not overdose the medication it can cause many side effects.
CDSCO APPROVAL: Drotaverine + Aceclofenac (80mg+ 100mg) Tablets approved by CDSCO in Indian in 15.09.2008.
FORMULATIONSAVAILABLE IN MARKET:
Drotaverine 40mg tablets
Drotaverine 80mg tablets
Drotaverine 40mg/2ml oral solution
Drotaverine 20mg/5ml oral solution
Drotaverine 10mg/5ml oral solution
Drotaverine 80mg + Diclofenac 50mg tablets
Drotaverine 40mg + Nimesulide 100mg tablets
Drotaverine 80mg + Aceclofenac100mg tablets
Note: Product protected by validpatents are not offered for sale in countries where such patents are stillvalid and its liability is at Buyers Risk