is the largest manufacturer and exporter of the Fluconazole among all over the world. Niksan Pharmaceutical is oneof biggest the supplier, manufacturer, exporter and distributor of the Fluconazole API and finishedformulations in Ankleshwar, Gujarat, India. The products ofNiksan Pharmaceutical and Niksan group companies are widely appreciated by theclients and other companies.
Niksan Pharmaceutical provides API and finishedformulations of Fluconazole in allover Indian states Like Kerala, Gujarat, Haryana, Rajasthan, Madhya Pradesh,Uttar Pradesh, Rajasthan, Karnataka, Meghalaya, Tamilnadu, Goa, Sikkim, Assam,Punjab, Delhi, Bihar, Jammu Kashmir Etc.
Niksan pharmaceutical is also large exporter ofthe API and finished pharmaceutical products of Fluconazole in many countries for years. The countries where weexporting are Zambia, Haiti, Ghana, Kenya, Jamaica, Cameroon, Uganda, Zimbabwe,Nigeria, Tanzania, Trinidad & Tobago, Puerto Rico, Nepal, Lebanon, SouthAfrica, United States, India, United Kingdom, Ireland, Canada, Bangladesh,Iraq, Pakistan, Philippines, United Arab Emirates, New Zealand, Malaysia, SriLanka, Australia, Poland, Jordan, Tunisia, Belgium, Algeria, Morocco,Singapore, Thailand, Indonesia, Romani, Saudi Arabia, Hong Kong, France,Vietnam, Hungary, Greece , Egypt, Israel, Switzerland, Taiwan, South Korea,Iran, Sweden, Netherlands, Colombia, Mexico , Brazil, Spain, Germany, Turkey,Italy, Russia and many more countries.
Fluconazole used in the treatment of fungal infection. Ithas anti-fungal activity and by this Fluconazole slows the growth of fungi thatcause infection. Fluconazole used in many fungal infections like blastomycosis, cryptococcosis, pityriasis versicolor,dermatophytosis, candidiasis, coccidiodomycosis.
SYNONYMS: Diflucan, Difluconazole,Fluconazol, Fluconazole, Fluconazolum, Triflucan.
IUPAC NAME:2-(2, 4-difluorophenyl)-1, 3-bis (1H-1, 2, 4-triazol-1-yl) propan-2-ol
CAS NO: 86386-73-4
MOLECULAR MASS: 306.27 g/mol
STORAGECONDITION: Store in cool and dry place. Keep medicine away from direct light andheat. Do not put medication in bathroom or any humid place. Keep away fromchildren and pets.
HOW TO USE: Take medicationorally ne time day. If you are taking the oral solution, kindly shake wellbefore use. To get more benefits of the mass: 306.27 g/mol medicinetake medicine regularly. Take your doctorâs advice if you have any confusionregarding to the medication.
HOW FLUCONAZOLE WORKS: Fluconazole reduce the growth of the fungi bydegrading or destroying the cell wall of fungi and by this action fungus cellscanât perform any other activity and by this Fluconazole gives the antifungalactivity.
PHARMACOKINETICS:90%Fluconazole absorbed after the oral administration, although theabsorption may comparable in oral dose and by IV dose. Fluconazole takes 3hoursto reach the peak plasma concentration. The protein binding of Fluconazole isvery low, only 11-12% of Fluconazole binds with the blood plasma protein. Thehalf-life of Fluconazole is approximately 30hours. Approximately 80% ofunchanged drug eliminated by the urination and remaining metabolites eliminatedby the feces.
SIDE EFFECTSOF FLUCONAZOLE: The common side effects like nausea, vomiting, dizziness, stomachpain, hair loss, stomach upset my seen in patients. If you see some seriousside effects like renal problem, loss of appetite, weight loss, tirednesscontact your doctor. Fluconazole rarely cause liver damage so if you seesymptoms like stomach or abdominal pain see medical attention.
PRECAUTIONS: If you haveallergic reaction from Fluconazole or any other azoles kindly tell your doctor.Fluconazole may cause fainting, dizziness, irregular heartbeats so if you haveany heart problem tell your doctor. Share your family history if they have anysugar problem.
CDSCO APPROVAL: Fluconazole (2%) + ZincPyrethione (1%) suspension approved by CDSCO in India in 22.02.2005,
Fluconazole Dispersible tablets 50mg approved by CDSCO in India in22.04.2008,
Framycetin + Hydrocortisone + Fluconazole topical cream approvedby CDSCO in India in 1987-April,
Fluconazole tablet 300mg (Additional strength) approved by CDSCOin India in 28.11.2011,
Fluconazole 400mg tablet approved by CDSCO in India in 03.03.2005,
Fluconazole + Secnidazole + Azithromycin approved by CDSCO inIndia in 07.06.1999,
Fluconazole for Oral suspension 50/200 mg per 5ml (Pack Size:35ml) approved by CDSCO in India in 20.08.2010,
Fluconazole + Zinc Pyrethrone (Each 30/60ml bottle contains: 2% +1%) Lotion approved by CDSCO in India in 15.09.2008,
Fluconazole eye drops approved by CDSCO in India in 04.02.1998,
Fluconazole tablets approved by CDSCO in India in April-2004
Fluconazole approved by CDSCO in India in 29.05.2000,
Posaconazole Oral Suspension 40mg/ml approved by CDSCO in India in18.07.2009,
Fluconazole capsules/injection approved by CDSCO in India in28.01.1993,
Fluconazole tabs/caps/inj. approved by CDSCO in India in26.04.1993,
Fluconazole tab approved by CDSCO in India in 2003,
Fluconazole topical gel (0.5%) approved by CDSCO in India in13.08.2004.
FORMULATION AVAILABLE IN MARKET:
Fluconazole (2%) + Zinc Pyrethione (1%) suspension
Fluconazole Dispersible tablets 50mg
Framycetin + Hydrocortisone + Fluconazole topical cream
Fluconazole 400mg tablets
Fluconazole + Secnidazole + Azithromycin tablets
Fluconazole for Oral suspension 50/200 mg per 5ml
Fluconazole + Zinc Pyrethrone (Each 30/60ml bottle contains: 2% +1%) Lotion
Fluconazole eye drops
Fluconazole topical gel (0.5%)
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