is leading manufacturer and distributer of the Lacosamide among the other countries. Niksan Pharmaceutical is oneof the major the supplier, distributer, exporter and manufacturer of the Lacosamide API andfinished formulations in Ankleshwar, Gujarat, India. The products of NiksanPharmaceutical and Niksan group companies are widely appreciated by the clientsand other companies.
Niksan Pharmaceutical is the supplier,manufacturer, exporter and trader of Lacosamide in the domestic level as well as the internationalmarket.
Niksan Pharmaceutical provides Lacosamide API in allover Indian states like Jammu & Kashmir, Himachal Pradesh, Uttarakhand,Punjab, Kerala, Chandigarh, Chhattisgarh, Andhra Pradesh, Rajasthan, Meghalaya, Mizoram,Nagaland, Orissa,, Dadra and NagarHaveli, Goa, Gujarat,Jharkhand, West Bengal, Karnataka, Kerala, Madhya Pradesh etc.
Niksan Pharmaceutical also provides Lacosamide API and finished formulations in all othercountries of the world like Germany, Switzerland, Poland, Latvia, Egypt,Lithuania, Estonia, Ukraine, Moldova, Russia, United States, Austria, Belarus,Serbia, India, Spain, Slovenia, Nigeria, Croatia, South Africa, Kazakhstan,Italy, Romania, Bulgaria, Portugal, South Korea, Greece, Philippines, Belgium,Saudi Arabia, Turkey, Japan etc.
Lacosamide is one type of anticonvulsants medication. Itworks by decreasing abnormal electrical activity in the brain.
SYNONYMS: Erlosamide, Harkoseride, Lacosamida,Lacosamide
IUPAC NAME: (2R)-N-benzyl-2-acetamido-3-methoxypropanamide
CAS NO: 175481-36-4
FORMULA: C13H18N2O3
MOLECULAR MASS:250.2936 g/mol
STORAGE OF LACOSAMIDE:stored in glass or polyvinyl chloride (PVC)bags at ambient room temperature 15-30°C (59-86°F).Keep all medicines out of reach of children. The oral solutionshould be used within 7 weeks of opening the bottle.
APPLICATIONS OF LACOSAMIDE:Lacosamide is used to control partial onset seizures (seizures that involve only one part of the brain) in adults andchildren 1 month of age and older.
HOW TO USE: Lacosamide comes as a tablet and as ansolution (liquid) to take by mouth. It is usually taken twice a day with or without food. Take lacosamide at around the same times every day.Follow the directions on your prescription label carefully, and ask your doctoror pharmacist to explain any part you do not understand.
HOW LACOSAMIDE WORKS: Lacosamide is anantiepileptic drug approved in the USA and Europe as adjunctive therapy forpartial-onset seizures. Studies suggest that lacosamide selectively enhances slow inactivationof voltage-gated sodium channels and possibly interacts with collapsin responsemediator protein-2.
CONTRAINDICATIONS OF LACOSAMIDE: Lacosamide is contraindicated in patients who havedemonstrated a hypersensitivity to the drug or its ingredients, Depression, suicidal ideation, Hepaticdisease, Phenylketonuria, Pregnancy, Breast-feeding.
PHARMACOKINETICS OF LACOSAMIDE: The maximumLacosamide plasma concentrations occur about 1-4 hours after oraladministration, and the pharmacokinetics of Lacosamide are dose proportional. Food does not affect absorption. approximately 0.6L/kg; thus close to the volume of total body water. Lacosamide is a CYP2C19substrate.
SIDE EFFECTS OF LACOSAMIDE Common lacosamide (Vimpat) side effectsinclude dizziness, headache, and nausea. Fatigue and vision changes are alsopossible. These side effects are more likely with higher doses of lacosamideand usually go awayover time.
PRECAUTIONS: you should know thatlacosamide may make you dizzy or drowsy and may cause blurred vision orproblems with coordination and balance. Do not drive a car, operate machinery, or participate inactivities requiring alertness or coordination until you know how thismedication affects you.
CDSCO APPROVAL:
Lacosamide film coated tablet 50mg/100mg /150mg /200mg are approved by CDSCO in India in 10.06.10
FORMULATION AVAILABLEIN MARKET:
Lacosamide film coated tablet 50mg/100mg /150mg /200mg
Lacosamide Injection 10mg/ml
Lacosamide Syrup15mg/ml
Note: Product protected by validpatents are not offered for sale in countries where such patents are stillvalid and its liability is at Buyers Risk
REFERENCES:
www.webmd.com
https://pubchem.ncbi.nlm.nih.gov
https://go.drugbank.com
https://cdscoonline.gov.in
https://www.wikipedia.org/
https://www.drugs.com
https://www.zaubacorp.com
https://www.practo.com/consult
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