DR OTAVERINE

Product Description

is words top leading manufacturer, exporter, trader and supplier of DrotaverineAPI as well as finished pharmaceutical products of Drotaverineamong the pharmaceutical companies. Our product Drotaverineis widely used and appreciated by our group companies and also ourcustomers and users all around the nations. We offer the Drotaverinein very affordable price.

Niksan Pharmaceutical provides API and finishedformulations of Drotaverine in allover Indian states Like Kerala, Gujarat, Haryana, Rajasthan, Madhya Pradesh,Uttar Pradesh, Rajasthan, Karnataka, Meghalaya, Tamilnadu, Goa, Sikkim, Assam,Punjab, Delhi, Bihar, Jammu Kashmir Etc.

Niksan Pharmaceutical is also large exporter ofthe API and finished pharmaceutical products of Drotaverine in many countries for years. The countries where weexporting are Myanmar (Burma), Nepal, Afghanistan, Uganda, Ghana, Yemen,Pakistan, Syria, Lithuania, Vietnam, Iraq, Nigeria, Thailand, Malaysia,Hungary, Romania, Egypt, Bolivia, Ukraine, Poland, United Kingdom, MexicoRussia, Germany, Canada, Turkey, United States, Spain, France and many morecountries.

Drotaverine is one type ofanti-spasmodic drug. Drotaverine is the posphodiesterase 4 inhibitor.

Drotaverine used to enhance thecervical dilation during the birth process. Drotaverine also treat the spasmand twitches the smooth muscle of the stomach.

SYNONYMS OF DROTAVERINE: Drotaverin, Drotaverina, Drotaverine,Drotaverinum.

IUPAC NAME: (1Z)-1-[(3, 4-diethoxyphenyl) methylidene]-6,7-diethoxy-1, 2, 3, 4-tetrahydroisoquinoline.

CAS NO:14009-24-6

FORMULA:C₂₄H₃₁NO₄

MOLECULAR MASS: 397.50 g/mol

STORAGE CONDITIONS: Store in room temperature in dry place. Donot put it in bathroom or fridge. Keep away from direct light and heat. Keepaway from children and pet.

HOW TO USE: Take the medicine orally with or withoutfood. If you have any confusion regarding to the medication ask your doctor. Takemedication regularly to achieve maximum benefits from it.

HOW DROTAVERINEWORKS: Drotaverine is anti-spasmodic drug which inhibits the phosphodiesterase4 enzyme and by this it cause vasodilation of the cervical muscle whiles thebirth process. It is also used in the treatment of headache and syndrome.

PHARMACOKINETICS: Drotaverine inhibits the phosphodiesterase4 enzyme and increase the cAMP concentration. The bioavaibility of Drotaverineis variable. About 80-95% the Drotaverine drug binds with the plasma protein. Thehalf-life of Drotaverine is between 7-12hrs. The elimination of the Drotaverineis done mainly by the bile.

SIDE EFFECTS: The side effects ofDrotaverine are nausea, vomiting, swelling of face, lips, tongue. Drotaverinealso cause dry mouth, change in pulse rate, Dizziness, headache.

PRECAUTIONS: Tell your doctor if youhave allergic reaction from the Drotaverine. If you have past disease likeliver disease, kidney problem or heart related problem kindly consult and tellyour doctor. Do not take alcohol or marijuana while taking the medication. Donot overdose the medication it can cause many side effects.

CDSCO APPROVAL: Drotaverine + Aceclofenac (80mg + 100mg)Tablets approved by CDSCO in Indian in 15.09.2008.

FORMULATIONSAVAILABLE IN MARKET:

Drotaverine 40mg tablets

Drotaverine 80mg tablets

Drotaverine 40mg/2ml oral solution

Drotaverine 20mg/5ml oral solution

Drotaverine 10mg/5ml oral solution

Drotaverine 80mg + Diclofenac 50mg tablets

Drotaverine 40mg + Nimesulide 100mg tablets

Drotaverine 80mg + Aceclofenac100mg tablets

Note: Product protected by valid patents are notoffered for sale in countries where such patents are still valid and itsliability is at Buyers Risk

REFERENCES:

www.webmd.com

https://pubchem.ncbi.nlm.nih.gov

https://go.drugbank.com

https://cdscoonline.gov.in

https://www.wikipedia.org/

https://www.drugs.com

https://www.zaubacorp.com

https://www.practo.com/consult