BILASTINE

Product Description

is leading manufacturer and distributer oftheBilastineamong the other countries. NiksanPharmaceutical is one of the major the supplier, distributer, exporter andmanufacturer of the BilastineAPI and finished formulations in Ankleshwar, Gujarat, India. The products ofNiksan Pharmaceutical and Niksan group companies are widely appreciated by theclients and other companies.

NiksanPharmaceutical is the supplier, manufacturer, exporter andtrader of Bilastine in thedomestic level as well as the international market. 

NiksanPharmaceutical provides BilastineAPI in all over Indianstates like Jammu & Kashmir, Himachal Pradesh, Uttarakhand, Punjab, Kerala,Chandigarh, Chhattisgarh, Andhra Pradesh, Rajasthan, Meghalaya, Mizoram, Nagaland, Orissa,, Dadra and Nagar Haveli, Goa,Gujarat, Jharkhand, West Bengal, Karnataka, Kerala, Madhya Pradesh etc.

NiksanPharmaceutical alsoprovides Bilastine API and finished formulations inall other countries of the world like Germany, Switzerland, Poland, Latvia,Egypt, Lithuania, Estonia, Ukraine, Moldova, Russia, United States, Austria,Belarus, Serbia, India, Spain, Slovenia, Nigeria, Croatia, South Africa,Kazakhstan, Italy, Romania, Bulgaria, Portugal, South Korea, Greece,Philippines, Belgium, Saudi Arabia, Turkey, Japan etc.

Bilastine is onetype of antihistamine medication used to treat hives (urticaria), allergic rhinitis and itchyinflamed eyes (allergic conjunctivitis) caused by an allergy. It is asecond-generation antihistamine and takes effect by selectively inhibiting thehistamine H₁ receptor, preventing these allergic reactions. 

SYNONYMS:Bilastina, Bilastine

IUPACNAME:2-[4-(2-{4-[1-(2-ethoxyethyl)-1H-1,3-benzodiazol-2-yl]piperidin-1-yl}ethyl)phenyl]-2-methylpropanoicacid

CASNO: 202189-78-4

FORMULA:C₂₈H₃₇N₃O₃

MOLECULARMASS: 463.6 g/mol

STORAGEOF BILASTINE:No special storage conditions are required.

APPLICATIONSOF BILASTINE:Bilastine is an antihistaminemedicine used widely to relieve allergicsymptoms like runny nose, sneezing, redness of the nose, watery eyes, itching,and rash. It stops the action of a naturalsubstance called histamine produced in your body during an allergic reaction.

HOWTO USE: 20 mg bilastine (1tablet) once daily for the relief of symptoms of allergic rhinoconjunctivitis(SAR and PAR) and urticaria. The tablet should be taken one hour before or two hours after intake of foodor fruit juice.

HOWBILASTINE WORKS: It works byblocking the effects of a chemical messenger known as histamine, which isnaturally involved in allergic reactions. Inshort, it helps to relieve the discomfort and unpleasant symptoms that occurreddue to allergic conditions, like blocked/runny/itchy nose, red/watery eyes, andskin rashes.

CONTRAINDICATIONSOF BILASTINE: Bilastine is contraindicated in patients who are hypersensitive to the activesubstance bilastine or to any of the excipients.Special warnings and precautions: Efficacy and safety of bilastine in childrenunder 12 years of age have not been established.

PHARMACOKINETICSOF BILASTINE: Bilastine has linearpharmacokinetics in the 2.5220 mg dose range in healthy adult subjects withoutevidence of accumulation after 14 days of treatment.

SIDE EFFECTS OF BILASTINE: In some cases, youmay experience abdominal pain,headache, dizziness, dry mouth, sore throat, nausea, cold-like nose symptoms(in children), or diarrhea (in children). Mostof these side effects of BILASTINE do not require medical attention andgradually resolve over time.

PRECAUTIONS: Before starting to use bilastine,talk to your pharmacist if you are suffering from moderate or severe kidneyfailure or if you are also taking other medicines. You should not take bilastine if you are allergicto bilastine or to any other component of this medicine.

CDSCO APPROVAL:

Bilastine are approved by CDSCO in India in14.01.2008

FORMULATION AVAILABLE IN MARKET:

Bilastine 10 MG Tablets

Bilastine 20 MG Tablets

Bilastine 20 MG& Montelukast 10 MG Tablet 

Note: Productprotected by valid patents are not offered for sale in countries where suchpatents are still valid and its liability is at Buyers Risk

REFERENCES:

www.webmd.com

https://pubchem.ncbi.nlm.nih.gov

https://go.drugbank.com

https://cdscoonline.gov.in

https://www.wikipedia.org/

https://www.drugs.com

https://www.zaubacorp.com

https://www.practo.com/consult